Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin

Cancer Science

Volumn 106, Issue 3, 2015, Pages 270-278

  Tsukigawa, Kenji ^a   Liao, Long ^a   Nakamura, Hideaki ^a   Fang, Jun ^a   Greish, Khaled ^a,b   Otagiri, Masaki ^a   Maeda, Hiroshi ^a  

^a SOJO UNIVERSITY   (Japan)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Antimetastatic property; Antitumor effect; Enhanced permeability and retention effect; Prolonged plasma half life; SMA THP conjugate

Indexed keywords

PIRARUBICIN; ZINOSTATIN MALEIC ACID STYRENE COPOLYMER; ANTINEOPLASTIC AGENT; DOXORUBICIN; DRUG CARRIER; MALEIC ACID DERIVATIVE; MICELLE; MITOCHONDRIAL PROTEIN; POLYSTYRENE DERIVATIVE; SPATA18 PROTEIN, HUMAN; STYRENE-MALEIC ACID POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CIRCULATION; CONTROLLED STUDY; COVALENT BOND; DRUG CONJUGATION; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT SCATTERING; LUNG METASTASIS; MALE; MICELLIZATION; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; TISSUE DISTRIBUTION; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; HELA CELL LINE; LUNG NEOPLASMS; MICELLE; RAT; SECONDARY; SPRAGUE DAWLEY RAT; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; HELA CELLS; HUMANS; LUNG NEOPLASMS; MALE; MALEATES; MICE; MICE, INBRED BALB C; MICELLES; MITOCHONDRIAL PROTEINS; POLYSTYRENES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84925785111     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12592     Document Type: Article

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