Feasibility study for intraepidermal delivery of proteins using a solid microneedle array

International Journal of Pharmaceutics

Volumn 486, Issue 1-2, 2015, Pages 52-58

  Witting, Madeleine ^a   Obst, Katja ^b   Pietzsch, Markus ^c   Friess, Wolfgang ^a   Hedtrich, Sarah ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Coating formulation; Human reconstructed skin; Protein stability; Proteins; Skin irritation; Solid microneedle array

Indexed keywords

PROTEIN; ANTIGEN; ASPARAGINASE; BOVINE SERUM ALBUMIN; INTERLEUKIN 6; INTERLEUKIN 8;

ANIMAL TISSUE; ARTICLE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG STORAGE; FEASIBILITY STUDY; FORCE; HUMAN; HUMAN TISSUE; MICRONEEDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; SOLID MICRONEEDLE ARRAY; ANIMAL; CHEMISTRY; IN VITRO STUDY; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; MICROINJECTION; NEEDLE; PIG; SKIN;

ANIMALS; ANTIGENS; ASPARAGINASE; FEASIBILITY STUDIES; HUMANS; IN VITRO TECHNIQUES; INJECTIONS, INTRADERMAL; INTERLEUKIN-6; INTERLEUKIN-8; MICROINJECTIONS; NEEDLES; SERUM ALBUMIN, BOVINE; SKIN; SWINE;

EID: 84925763795     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.03.046     Document Type: Article

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