The PKD inhibitor CID755673 enhances cardiac function in diabetic db/db mice

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Venardos, Kylie ^a   De Jong, Kirstie A ^a   Elkamie, Mansour ^a   Connor, Timothy ^a   McGee, Sean L ^a,b  

^a DEAKIN UNIVERSITY   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC AGENT; CID 755673; INSULIN; PROTEIN KINASE D; PROTEIN KINASE D1; PROTEIN KINASE D2; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; AZEPINE DERIVATIVE; BENZOFURAN DERIVATIVE; CID755673; PROTEIN KINASE C; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIASTOLIC DYSFUNCTION; DISEASE SEVERITY; DOSE RESPONSE; ECHOCARDIOGRAPHY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FOOD INTAKE; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; HEART FUNCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HEART WEIGHT; HISTOPATHOLOGY; HORMONE ACTION; MALE; MOUSE; MOUSE MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC DYSFUNCTION; TREATMENT DURATION; VALIDATION PROCESS; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPLICATION; DIABETIC CARDIOMYOPATHIES; DISEASE MODEL; DRUG EFFECTS; GENETICS; HEART; HEART MUSCLE; HEART VENTRICLE FUNCTION; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

MUS;

ANIMALS; AZEPINES; BENZOFURANS; DIABETES MELLITUS, TYPE 2; DIABETIC CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HEART; MALE; MICE; MYOCARDIUM; ORGAN SIZE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; TRANSCRIPTOME; VENTRICULAR DYSFUNCTION; VENTRICULAR FUNCTION, LEFT;

EID: 84925725824     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120934     Document Type: Article

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