Overexpression of AMP-activated protein kinase or protein kinase D prevents lipid-induced insulin resistance in cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 55, Issue 1, 2013, Pages 165-173

  Steinbusch, Laura K M ^a   Dirkx, Ellen ^a   Hoebers, Nicole T H ^a   Roelants, Veronique ^b   Foretz, Marc ^c   Viollet, Benoit ^c   Diamant, Michaela ^d   van Eys, Guillaume ^a   Ouwens, D Margriet ^e,f   Bertrand, Luc ^b   Glatz, Jan F C ^a   Luiken, Joost J F P ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c INSTITUT COCHIN   (France)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^f GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

AMPK; Cardiac metabolism; Insulin resistance; Lipid accumulation; Protein kinase D; Treatment

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PALMITIC ACID; PROTEIN KINASE D; TRIACYLGLYCEROL;

ADENOVIRUS; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; GLUCOSE TRANSPORT; HEART MUSCLE CELL; INSULIN RESISTANCE; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; GENE EXPRESSION; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MYOCYTES, CARDIAC; PALMITATES; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84872684367     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.11.005     Document Type: Article

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