Low shear stress induced HMGB1 translocation and release via PECAM-1/ PARP-1 pathway to induce inflammation response

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Qin, Wei Dong ^a   Mi, Shao Hua ^b   Li, Chen ^a   Wang, Gui Xia ^c   Zhang, Jian Ning ^a   Wang, Hao ^a   Zhang, Fan ^a   Ma, Yang ^a   Wu, Da Wei ^a   Zhang, Mingxiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b YANTAI YUHUANGDING HOSPITAL   (China)

^c LINYI PEOPLE'S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TUMOR NECROSIS FACTOR ALPHA; INTERCELLULAR ADHESION MOLECULE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

ARTICLE; ATHEROSCLEROSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ADHERENCE; LOW SHEAR STRESS; MONOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SHEAR STRESS; TIME; UMBILICAL VEIN ENDOTHELIAL CELL; UNDISTURBED SHEAR STRESS; ANTAGONISTS AND INHIBITORS; MECHANICAL STRESS; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT; SECRETION (PROCESS); SHEAR STRENGTH; SIGNAL TRANSDUCTION; TIME FACTOR; UPREGULATION;

ANTIGENS, CD31; HMGB1 PROTEIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; SHEAR STRENGTH; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TIME FACTORS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84925682760     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120586     Document Type: Article

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