The BDNF Val66Met variant affects gene expression through miR-146b

Neurobiology of Disease

Volumn 77, Issue , 2015, Pages 228-237

  Hsu, Pei Ken ^a   Xu, Bin ^a   Mukai, Jun ^a   Karayiorgou, Maria ^a   Gogos, Joseph A ^a  

^a Department of Physiology and Cellular Biophysics Columbia University ^*  (United States)

Author keywords

BDNF; Knock in mice; MicroRNA; Val66Met

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MESSENGER RNA; MICRORNA; MICRORNA 146B; PER1 PROTEIN; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CIRCADIAN RHYTHM SIGNALING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, MOUSE; METHIONINE; MIRN146 MICRORNA, MOUSE; NPAS4 PROTEIN, MOUSE; PER1 PROTEIN, MOUSE; VALINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BDNF GENE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; HIPPOCAMPUS; IN VITRO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NPAS4 GENE; NUCLEOTIDE SEQUENCE; PER1 GENE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WESTERN BLOTTING; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; TRANSGENIC MOUSE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRAIN-DERIVED NEUROTROPHIC FACTOR; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; IN VITRO TECHNIQUES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; METHIONINE; MICE; MICE, TRANSGENIC; MICRORNAS; MOLECULAR SEQUENCE DATA; PERIOD CIRCADIAN PROTEINS; VALINE;

EID: 84925677251     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.03.004     Document Type: Article

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