Laser-induced breakdown spectroscopy: A new approach for nanoparticle's mapping and quantification in organ tissue

Journal of Visualized Experiments

Volumn , Issue 88, 2014, Pages

  Sancey, Lucie ^a   Motto Ros, Vincent ^a   Kotb, Shady ^a   Wang, Xiaochun ^a   Lux, François ^a   Panczer, Gérard ^a   Yu, Jin ^a   Tillement, Olivier ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Biomedical measurement; Chemical images of organ tissue; Diagnosis; Elemental mapping; Inorganic chemistry; Issue 88; Laser induced breakdown spectroscopy; Laser induced plasma; Microtechnology; Nanoparticles; Nanotechnology; Organic chemistry; Physical chemistry; Physics; Plasma physics; Quantification; Spectrochemical analysis; Tissue mapping; Tissues

Indexed keywords

EID: 84925652756     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/51353     Document Type: Article

References (18)

1. Smith, M. A., Harris, P. L., Sayre, L. M., & Perry, G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proceedings of the National Academy of Sciences of the United States of America. 94, 9866-9868 (1997).
2. Wang, Y., Zhu, S., Weisman, G. A., Gitlin, J. D., & Petris, M. J. Conditional knockout of the Menkes disease copper transporter demonstrates its critical role in embryogenesis. PloS one. 7, e43039, doi:10.1371/journal.pone.0043039 (2012).
3. Reske-Nielson, E., Lou, H. O., Andersen, P., & Vagn-Hansen, P. Brain-copper concentration in Menkes' disease. Lancet. 1, 613 (1973).
4. Hayashi, H. et al. Various copper and iron overload patterns in the livers of patients with Wilson disease and idiopathic copper toxicosis. Medical molecular morphology 46, doi:10.1007/s00795-013-0015-2 (2013).
5. Lobinski, R., Moulin, C., & Ortega, R. Imaging and speciation of trace elements in biological environment. Biochimie. 88, 1591-1604, doi:10.1016/j.biochi.2006.10.003 (2006).
6. Devès, G., Bouhacina, T., & Ortega, R. STIM mass measurements for quantitative trace element analysis within biological samples and validation using AFM thickness measurements. Spectrochimica Acta B. 59, 1733-1738 (2004).
7. Twining, B. S. et al. Quantifying trace elements in individual aquatic protist cells with a synchrotron X-ray fluorescence microprobe. Analytical chemistry. 75, 3806-3816 (2003).
8. Guerquin-Kern, J. L., Wu, T. D., Quintana, C., & Croisy, A. Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy). Biochimica et biophysica acta. 1724, 228-238, doi:10.1016/j.bbagen.2005.05.013 (2005).
9. Binet, M. R., Ma, R., McLeod, C. W., & Poole, R. K. Detection and characterization of zinc-and cadmium-binding proteins in Escherichia coli by gel electrophoresis and laser ablation-inductively coupled plasma-mass spectrometry. Analytical biochemistry. 318, 30-38 (2003).
10. Becker, J., Gorbunoff, A., Zoriy, M., Izmer, A., & Kayser, M. Evidence of near-field laser ablation inductively coupled plasma mass spectrometry (NF-LA-ICP-MS) at nanometre scale for elemental and isotopic analysis on gels and biological samples. J. Anal. Atom. Spectrom. 21, 19-25 (2006).
11. Seeley, E. H., & Caprioli, R. M. 3D imaging by mass spectrometry: a new frontier. Analytical chemistry. 84, 2105-2110, doi:10.1021/ac2032707 (2012).
12. Pornwilard, M.-M., Weiskirchen, R., Gassler, N., Bosserhoff, A. K., & Becker, J. S. Novel bioimaging techniques of metals by laser ablation inductively coupled plasma mass spectrometry for diagnosis of fibrotic and cirrhotic liver disorders. PloS one. 8, e58702, doi:10.1371/journal.pone.0058702 (2013).
13. Cremers, D. A., & Radziemski, L. J. Handbook of laser-induced breakdown spectroscopy. Wiley; (2006).
14. Miziolek, A. W., & Palleschi, V. Laser-Induced Breakdown Spectroscopy: Fundamentals and Applications. (2006).
15. Motto-Ros, V. et al. Mapping nanoparticles injected into a biological tissue using laser-induced breakdown spectroscopy. Spectrochimica Acta Part B, doi:http://dx.doi.org/10.1016/j.sab.2013.05.020 (2013).
16. Motto-Ros, V. et al. Mapping of native inorganic elements and injected nanoparticles in a biological organ with laser-induced plasma. Applied Physics Letters. 101, 223702 (2012).
17. Mignot, A. et al. A top-down synthesis route to ultrasmall multifunctional Gd-based silica nanoparticles for theranostic applications. Chemistry. 19, 6122-6136, doi:10.1002/chem.201203003 (2013).
18. Lux, F. et al. Ultrasmall rigid particles as multimodal probes for medical applications. Angew Chem Int Ed Engl. 50, 12299-12303, doi:10.1002/anie.201104104 (2011).