A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid

Alzheimer's Research and Therapy

Volumn 7, Issue 1, 2015, Pages

  Yang, Ting ^a   O'Malley, Tiernan T ^a   Kanmert, Daniel ^a   Jerecic, Jasna ^b   Zieske, Lynn R ^c   Zetterberg, Henrik ^d,e   Hyman, Bradley T ^f   Walsh, Dominic M ^a   Selkoe, Dennis J ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Acumen Pharmaceuticals Inc   (United States)

^c SINGULEX INC   (United States)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; MONOCLONAL ANTIBODY; MONOMER; OLIGOMER; SYNTHETIC PEPTIDE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN HOMOGENATE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ELISA KIT; ENZYME LINKED IMMUNOSORBENT ASSAY; ERENNA IMMUNOASSAY; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IMMUNOASSAY ANALYZER; IMMUNODETECTION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MILD COGNITIVE IMPAIRMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING;

EID: 84925624029     PISSN: None     EISSN: 17589193     Source Type: Journal    
DOI: 10.1186/s13195-015-0100-y     Document Type: Article

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