The PI3K-Akt-eNOS pathway is involved in aortic hyporeactivity to Phenylephrine associated with late pregnancy in spontaneously hypertensive rats

Life Sciences

Volumn 122, Issue 1, 2015, Pages 78-86

  Zancheta, Dalise ^a,b   Troiano, Jéssica A ^a,b   Potje, Simone R ^a,b   Cavalari, Priscila ^b,c   Sumida, Doris H ^a,b   Antoniali, Cristina ^a,b  

^a Programa de Pos Graduacao Multicentrico em Ciencias Fisiologicas SBFis   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c PAULISTA UNIVERSITY   (Brazil)

Author keywords

Aorta; Nitric oxide; Phenylephrine; Pregnancy; Spontaneously hypertensive rats; Wortmannin

Indexed keywords

4,5 DIAMINOFLUORESCEIN DIACETATE; ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUO 3; NITRIC OXIDE; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; WORTMANNIN; ANDROSTANE DERIVATIVE; NOS3 PROTEIN, RAT; PROTEIN KINASE INHIBITOR; VASOCONSTRICTOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; AORTA; AORTIC HYPOREACTIVITY; ARTICLE; BIOAVAILABILITY; BLOOD VESSEL REACTIVITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; EVALUATION STUDY; FEMALE; FLOW CYTOMETRY; HOMOGENATE; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLETHYSMOGRAPHY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; THIRD TRIMESTER PREGNANCY; UPREGULATION; VASCULAR RING; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; PREGNANCY; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

ANDROSTADIENES; ANIMALS; AORTA; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; NITRIC OXIDE SYNTHASE TYPE III; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL 3-KINASES; PREGNANCY; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED SHR; RATS, WISTAR; VASOCONSTRICTOR AGENTS;

EID: 84925581632     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.12.014     Document Type: Article

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