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Volumn 54, Issue 2, 2015, Pages 324-331

Sex-dependent differential activation of NLRP3 and AIM2 inflammasomes in SLE macrophages

Author keywords

Inflammasome; Macrophage; Sex; Systemic lupus erythematosus

Indexed keywords

ABSENT IN MELANOMA 2; AUTOANTIBODY; CASPASE RECRUITMENT DOMAIN FAMILY MEMBER 8; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CRYOPYRIN; DOUBLE STRANDED DNA; INFLAMMASOME; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; UNCLASSIFIED DRUG; AIM2 PROTEIN, HUMAN; BIOLOGICAL MARKER; CARRIER PROTEIN; DNA; DNA BINDING PROTEIN; NEOPTERIN; NLRP3 PROTEIN, HUMAN;

EID: 84925581290     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keu318     Document Type: Article
Times cited : (118)

References (26)
  • 1
    • 84885954878 scopus 로고    scopus 로고
    • Sexual disparities in the incidence and course of SLE and RA
    • Tedeschi SK, Bermas B, Costenbader KH. Sexual disparities in the incidence and course of SLE and RA. Clin Immunol 2013;149:211–8.
    • (2013) Clin Immunol , vol.149 , pp. 211-218
    • Tedeschi, S.K.1    Bermas, B.2    Costenbader, K.H.3
  • 2
    • 84862294227 scopus 로고    scopus 로고
    • Gender differences in the pathogenesis and outcome of lupus and of lupus nephritis
    • Schwartzman-Morris J, Putterman C. Gender differences in the pathogenesis and outcome of lupus and of lupus nephritis. Clin Dev Immunol 2012;2012:604892.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 604892
    • Schwartzman-Morris, J.1    Putterman, C.2
  • 3
    • 84859508343 scopus 로고    scopus 로고
    • Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus
    • Hughes T, Adler A, Merrill JT et al. Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis 2012;715:694–9.
    • (2012) Ann Rheum Dis , vol.715 , pp. 694-699
    • Hughes, T.1    Adler, A.2    Merrill, J.T.3
  • 4
    • 79951671510 scopus 로고    scopus 로고
    • IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
    • Krausgruber T, Blazek K, Smallie T et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol 2011;123:231–8.
    • (2011) Nat Immunol , vol.123 , pp. 231-238
    • Krausgruber, T.1    Blazek, K.2    Smallie, T.3
  • 6
    • 77950304735 scopus 로고    scopus 로고
    • CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis
    • Kastbom A, Johansson M, Verma D, Soderkvist P, Rantapaa-Dahlqvist S. CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis. Ann Rheum Dis 2009;694:723–6.
    • (2009) Ann Rheum Dis , vol.694 , pp. 723-726
    • Kastbom, A.1    Johansson, M.2    Verma, D.3    Soderkvist, P.4    Rantapaa-Dahlqvist, S.5
  • 7
    • 40549084310 scopus 로고    scopus 로고
    • Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases
    • Verma D, Lerm M, Blomgran Julinder R et al. Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases? Arthritis Rheum 2008;583:888–94.
    • (2008) Arthritis Rheum , vol.583 , pp. 888-894
    • Verma, D.1    Lerm, M.2    Blomgran Julinder, R.3
  • 8
    • 84879205728 scopus 로고    scopus 로고
    • AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation
    • Zhang W, Cai Y, Xu W et al. AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation. J Clin Immunol 2013;33:925–37.
    • (2013) J Clin Immunol , vol.33 , pp. 925-937
    • Zhang, W.1    Cai, Y.2    Xu, W.3
  • 9
    • 82455175944 scopus 로고    scopus 로고
    • Cell type and gender-dependent differential regulation of the p202 and Aim2 proteins: implications for the regulation of innate immune responses in SLE
    • Panchanathan R, Duan X, Arumugam M et al. Cell type and gender-dependent differential regulation of the p202 and Aim2 proteins: implications for the regulation of innate immune responses in SLE. Mol Immunol 2011;49:273–80.
    • (2011) Mol Immunol , vol.49 , pp. 273-280
    • Panchanathan, R.1    Duan, X.2    Arumugam, M.3
  • 10
    • 1242351229 scopus 로고    scopus 로고
    • Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes
    • Hamann L, Hamprecht A, Gomma A, Schumann RR. Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes. J Immunol Methods 2004;2852:281–91.
    • (2004) J Immunol Methods , vol.2852 , pp. 281-291
    • Hamann, L.1    Hamprecht, A.2    Gomma, A.3    Schumann, R.R.4
  • 11
    • 79957533121 scopus 로고    scopus 로고
    • Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis
    • Rho YH, Solus J, Raggi P et al. Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Care Res 2011;634: 535–41.
    • (2011) Arthritis Care Res , vol.634 , pp. 535-541
    • Rho, Y.H.1    Solus, J.2    Raggi, P.3
  • 12
    • 28244459680 scopus 로고    scopus 로고
    • Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kB-driven protein synthesis
    • 17511
    • Kahlenberg JM, Lundberg KC, Kertesy SB, Qu Y, Dubyak GR. Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kB-driven protein synthesis. J Immunol 2005;17511: 7611–22.
    • (2005) J Immunol , pp. 7611-7622
    • Kahlenberg, J.M.1    Lundberg, K.C.2    Kertesy, S.B.3    Qu, Y.4    Dubyak, G.R.5
  • 13
    • 84870514546 scopus 로고    scopus 로고
    • ATP release and purinergic signaling: a common pathway for particlemediated inflammasome activation
    • Riteau N, Baron L, Villeret B et al. ATP release and purinergic signaling: a common pathway for particlemediated inflammasome activation. Cell Death Dis 2012;3: e403.
    • (2012) Cell Death Dis , vol.3
    • Riteau, N.1    Baron, L.2    Villeret, B.3
  • 14
    • 84873550853 scopus 로고    scopus 로고
    • Self double-stranded (ds)DNA induces IL-1beta production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies
    • Shin MS, Kang Y, Lee N et al. Self double-stranded (ds)DNA induces IL-1beta production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies. J Immunol 2013;1904:1407–15.
    • (2013) J Immunol , pp. 1407-1415
    • Shin, M.S.1    Kang, Y.2    Lee, N.3
  • 15
    • 0033007975 scopus 로고    scopus 로고
    • Estrogen enhancement of anti-double-stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    • Kanda N, Tsuchida T, Tamaki K. Estrogen enhancement of anti-double-stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Arthritis Rheum 1999;422:328–37.
    • (1999) Arthritis Rheum , pp. 328-337
    • Kanda, N.1    Tsuchida, T.2    Tamaki, K.3
  • 16
    • 66949174089 scopus 로고    scopus 로고
    • Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
    • Schoultz I, Verma D, Halfvarsson J et al. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am J Gastroenterol 2009;1045:1180–8.
    • (2009) Am J Gastroenterol , vol.1045 , pp. 1180-1188
    • Schoultz, I.1    Verma, D.2    Halfvarsson, J.3
  • 17
    • 77953123031 scopus 로고    scopus 로고
    • The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: a reappraisal
    • Katsiari CG, Liossis SN, Sfikakis PP. The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: a reappraisal. Semin Arthritis Rheum 2009;396:491–503.
    • (2009) Semin Arthritis Rheum , vol.396 , pp. 491-503
    • Katsiari, C.G.1    Liossis, S.N.2    Sfikakis, P.P.3
  • 19
    • 16844378971 scopus 로고    scopus 로고
    • Hormonal modulation of B cell development and repertoire selection
    • Grimaldi CM, Hill L, Xu X, Peeva E, Diamond B. Hormonal modulation of B cell development and repertoire selection. Mol Immunol 2005;427:811–20.
    • (2005) Mol Immunol , vol.427 , pp. 811-820
    • Grimaldi, C.M.1    Hill, L.2    Xu, X.3    Peeva, E.4    Diamond, B.5
  • 20
    • 46849085591 scopus 로고    scopus 로고
    • Hormonal regulation of B-cell function and systemic lupus erythematosus
    • Cohen-Solal JF, Jeganathan V, Hill L et al. Hormonal regulation of B-cell function and systemic lupus erythematosus. Lupus 2008;176:528–32.
    • (2008) Lupus , vol.176 , pp. 528-532
    • Cohen-Solal, J.F.1    Jeganathan, V.2    Hill, L.3
  • 21
    • 78650674088 scopus 로고    scopus 로고
    • Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus
    • Panchanathan R, Duan X, Shen H et al. Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus. J Immunol 2010;18512:7385–93.
    • (2010) J Immunol , pp. 7385-7393
    • Panchanathan, R.1    Duan, X.2    Shen, H.3
  • 22
    • 79951482447 scopus 로고    scopus 로고
    • Genderdependent expression of murine Irf5 gene: implications for sex bias in autoimmunity
    • Shen H, Panchanathan R, Rajavelu P et al. Genderdependent expression of murine Irf5 gene: implications for sex bias in autoimmunity. J Mol Cell Biol 2010;25:284–90.
    • (2010) J Mol Cell Biol , vol.25 , pp. 284-290
    • Shen, H.1    Panchanathan, R.2    Rajavelu, P.3
  • 23
    • 77955327573 scopus 로고    scopus 로고
    • IRF5 and B cells in lupus development
    • Beal E. IRF5 and B cells in lupus development. Nat Rev Rheumatol 2010;68:437.
    • (2010) Nat Rev Rheumatol , vol.68
    • Beal, E.1
  • 24
    • 73349110966 scopus 로고    scopus 로고
    • Female and male sex hormones differentially regulate expression of Ifi202, an interferon-inducible lupus susceptibility gene within the Nba2 interval
    • Panchanathan R, Shen H, Bupp MG, Gould KA, Choubey D. Female and male sex hormones differentially regulate expression of Ifi202, an interferon-inducible lupus susceptibility gene within the Nba2 interval. J Immunol 2009;18311:7031–8.
    • (2009) J Immunol , pp. 7031-7038
    • Panchanathan, R.1    Shen, H.2    Bupp, M.G.3    Gould, K.A.4    Choubey, D.5
  • 25
    • 84855368604 scopus 로고    scopus 로고
    • Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis
    • Panchanathan R, Liu H, Liu H et al. Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis. J Immunol 2012;1881:270–8.
    • (2012) J Immunol , pp. 270-278
    • Panchanathan, R.1    Liu, H.2    Liu, H.3
  • 26
    • 84858753280 scopus 로고    scopus 로고
    • Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus
    • 382-3
    • Strickland FM, Hewagama A, Lu Q et al. Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus. J Autoimmun 2012;382-3:J135–43.
    • (2012) J Autoimmun , pp. J135-J143
    • Strickland, F.M.1    Hewagama, A.2    Lu, Q.3


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