-
1
-
-
84892794580
-
Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells
-
COI: 1:CAS:528:DC%2BC3sXhsleltLbM, PID: 24193916
-
Ashour AA, Abdel-Aziz AA, Mansour AM et al (2014) Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells. Apoptosis 19:241–258
-
(2014)
Apoptosis
, vol.19
, pp. 241-258
-
-
Ashour, A.A.1
Abdel-Aziz, A.A.2
Mansour, A.M.3
-
2
-
-
84869119665
-
Upregulation of trefoil factor 3 (TFF3) after rectal cancer chemoradiotherapy is an adverse prognostic factor and a potential therapeutic target
-
COI: 1:CAS:528:DC%2BC38XlvFKhsbY%3D, PID: 22516806
-
Casado E, Garcia VM, Sánchez JJ et al (2012) Upregulation of trefoil factor 3 (TFF3) after rectal cancer chemoradiotherapy is an adverse prognostic factor and a potential therapeutic target. Int J Radiat Oncol Biol Phys 84:1151–1158
-
(2012)
Int J Radiat Oncol Biol Phys
, vol.84
, pp. 1151-1158
-
-
Casado, E.1
Garcia, V.M.2
Sánchez, J.J.3
-
3
-
-
78650174827
-
Nonlethal aluminum maltolate can reduce brain-derived neurotrophic factor-induced Arc expression through interrupting the ERK signaling in SH-SY5Y neuroblastoma cells
-
COI: 1:CAS:528:DC%2BC3cXhsFylu7rP, PID: 21040763
-
Chen TJ, Cheng HM, Wang DC et al (2011a) Nonlethal aluminum maltolate can reduce brain-derived neurotrophic factor-induced Arc expression through interrupting the ERK signaling in SH-SY5Y neuroblastoma cells. Toxicol Lett 200:67–76
-
(2011)
Toxicol Lett
, vol.200
, pp. 67-76
-
-
Chen, T.J.1
Cheng, H.M.2
Wang, D.C.3
-
4
-
-
83755181311
-
1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor
-
COI: 1:CAS:528:DC%2BC3MXhs1ahtbjM, PID: 22020937
-
Chen Z, Gopalakrishnan SM, Bui MH et al (2011b) 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J Biol Chem 286:43951–43958
-
(2011)
J Biol Chem
, vol.286
, pp. 43951-43958
-
-
Chen, Z.1
Gopalakrishnan, S.M.2
Bui, M.H.3
-
5
-
-
79953298761
-
eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206
-
COI: 1:CAS:528:DC%2BC3MXktVOjtbg%3D, PID: 21307130
-
Cheng Y, Ren X, Zhang Y et al (2011) eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206. Cancer Res 71:2654–2663
-
(2011)
Cancer Res
, vol.71
, pp. 2654-2663
-
-
Cheng, Y.1
Ren, X.2
Zhang, Y.3
-
6
-
-
84858249902
-
Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact
-
COI: 1:CAS:528:DC%2BC38XisFCks70%3D, PID: 22352903
-
Devkota AK, Tavares CD, Warthaka M et al (2012) Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact. Biochemistry 51:2100–2112
-
(2012)
Biochemistry
, vol.51
, pp. 2100-2112
-
-
Devkota, A.K.1
Tavares, C.D.2
Warthaka, M.3
-
7
-
-
84863727484
-
A novel role for Bcl-2 in regulation of cellular calcium extrusion
-
COI: 1:CAS:528:DC%2BC38XoslGqu7o%3D, PID: 22704985
-
Ferdek PE, Gerasimenko JV, Peng S et al (2012) A novel role for Bcl-2 in regulation of cellular calcium extrusion. Curr Biol 22:1241–1246
-
(2012)
Curr Biol
, vol.22
, pp. 1241-1246
-
-
Ferdek, P.E.1
Gerasimenko, J.V.2
Peng, S.3
-
8
-
-
38049093745
-
Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy
-
COI: 1:CAS:528:DC%2BD1cXks1Sgsro%3D, PID: 18000394
-
Gills JJ, Lopiccolo J, Dennis PA (2008) Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy. Autophagy 4:107–109
-
(2008)
Autophagy
, vol.4
, pp. 107-109
-
-
Gills, J.J.1
Lopiccolo, J.2
Dennis, P.A.3
-
9
-
-
84885415115
-
Hypoxia integration in the serological proteome analysis unmasks tumor antigens and fosters the identification of anti-phospho-eEF2 antibodies as potential cancer biomarkers
-
COI: 1:CAS:528:DC%2BC3sXhs1equ7fK, PID: 24130777
-
Grandjean M, Sermeus A, Branders S et al (2013) Hypoxia integration in the serological proteome analysis unmasks tumor antigens and fosters the identification of anti-phospho-eEF2 antibodies as potential cancer biomarkers. PLoS One 8:e76508
-
(2013)
PLoS One
, vol.8
, pp. e76508
-
-
Grandjean, M.1
Sermeus, A.2
Branders, S.3
-
10
-
-
84873050996
-
Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase
-
COI: 1:CAS:528:DC%2BC3sXltVOitLg%3D, PID: 23184662
-
Hizli AA, Chi Y, Swanger J et al (2013) Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. Mol Cell Biol 33:596–604
-
(2013)
Mol Cell Biol
, vol.33
, pp. 596-604
-
-
Hizli, A.A.1
Chi, Y.2
Swanger, J.3
-
11
-
-
84901463783
-
Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles
-
COI: 1:CAS:528:DC%2BC2cXht1WqtL7E, PID: 24853390
-
Kenney JW, Moore CE, Wang X et al (2014) Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles. Adv Biol Regul 55:15–27
-
(2014)
Adv Biol Regul
, vol.55
, pp. 15-27
-
-
Kenney, J.W.1
Moore, C.E.2
Wang, X.3
-
12
-
-
84871730845
-
Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors
-
COI: 1:CAS:528:DC%2BC3sXhsFelug%3D%3D, PID: 23087377
-
Kurata S, Shen B, Liu JO et al (2013) Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors. Nucleic Acids Res 41:264–276
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 264-276
-
-
Kurata, S.1
Shen, B.2
Liu, J.O.3
-
13
-
-
84878271546
-
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
-
COI: 1:CAS:528:DC%2BC3sXotlGltLg%3D, PID: 23706743
-
Leprivier G, Remke M, Rotblat B et al (2013) The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell 153:1064–1079
-
(2013)
Cell
, vol.153
, pp. 1064-1079
-
-
Leprivier, G.1
Remke, M.2
Rotblat, B.3
-
14
-
-
84904172878
-
Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development
-
COI: 1:CAS:528:DC%2BC2cXhs1Oqur3L, PID: 25045273
-
Mencalha AL, Corrêa S, Abdelhay E (2014) Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development. Onco Targets Ther 7:1247–1254
-
(2014)
Onco Targets Ther
, vol.7
, pp. 1247-1254
-
-
Mencalha, A.L.1
Corrêa, S.2
Abdelhay, E.3
-
15
-
-
84867787383
-
Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer
-
COI: 1:CAS:528:DC%2BC3sXjslyqs7o%3D, PID: 23102376
-
Meric-Bernstam F, Chen H, Akcakanat A et al (2012) Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer. Breast Cancer Res 14:R138
-
(2012)
Breast Cancer Res
, vol.14
, pp. R138
-
-
Meric-Bernstam, F.1
Chen, H.2
Akcakanat, A.3
-
16
-
-
84878390397
-
The role of eukaryotic elongation factor 2 kinase in rapid antidepressant action of ketamine
-
COI: 1:CAS:528:DC%2BC38XhsFSnsbjE, PID: 23062356
-
Monteggia LM, Gideons E, Kavalali ET et al (2013) The role of eukaryotic elongation factor 2 kinase in rapid antidepressant action of ketamine. Biol Psychiatry 73:1199–1203
-
(2013)
Biol Psychiatry
, vol.73
, pp. 1199-1203
-
-
Monteggia, L.M.1
Gideons, E.2
Kavalali, E.T.3
-
17
-
-
84872126340
-
Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kgamma in the MDA-MB-231 metastatic breast cancer cell line
-
COI: 1:CAS:528:DC%2BC3sXjt1aktLc%3D, PID: 23320409
-
Niu M, Klingler-Hoffmann M, Brazzatti JA et al (2013) Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kgamma in the MDA-MB-231 metastatic breast cancer cell line. Proteome Sci 11:4
-
(2013)
Proteome Sci
, vol.11
, pp. 4
-
-
Niu, M.1
Klingler-Hoffmann, M.2
Brazzatti, J.A.3
-
18
-
-
84863230655
-
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
-
COI: 1:CAS:528:DC%2BC38XivV2iu7o%3D, PID: 22216903
-
Pyr Dit Ruys S, Wang X, Smith EM et al (2012) Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase. Biochem J 442:681–692
-
(2012)
Biochem J
, vol.442
, pp. 681-692
-
-
Pyr Dit Ruys, S.1
Wang, X.2
Smith, E.M.3
-
19
-
-
41949107421
-
cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner
-
COI: 1:CAS:528:DC%2BD1cXksVagtLs%3D, PID: 18337751
-
Smith EM, Proud CG (2008) cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J 27:1005–1016
-
(2008)
EMBO J
, vol.27
, pp. 1005-1016
-
-
Smith, E.M.1
Proud, C.G.2
-
20
-
-
84922279700
-
Clinical value of eukaryotic elongation factor 2 (eEF2) in non-small cell lung cancer patients
-
Sun HG, Dong XJ, Lu T et al (2013) Clinical value of eukaryotic elongation factor 2 (eEF2) in non-small cell lung cancer patients. Asian Pac J Cancer Prev 14:6533–6535
-
(2013)
Asian Pac J Cancer Prev
, vol.14
, pp. 6533-6535
-
-
Sun, H.G.1
Dong, X.J.2
Lu, T.3
-
21
-
-
84864094070
-
Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer
-
COI: 1:CAS:528:DC%2BC38XhtFSkt73P, PID: 22911754
-
Tekedereli I, Alpay SN, Tavares CD et al (2012) Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer. PLoS One 7:e41171
-
(2012)
PLoS One
, vol.7
, pp. e41171
-
-
Tekedereli, I.1
Alpay, S.N.2
Tavares, C.D.3
-
22
-
-
70350574128
-
The role of protein synthesis in cell cycling and cancer
-
COI: 1:CAS:528:DC%2BC3cXjvFGjurk%3D, PID: 19546037
-
White-Gilbertson S, Kurtz DT, Voelkel-Johnson C (2009) The role of protein synthesis in cell cycling and cancer. Mol Oncol 3:402–408
-
(2009)
Mol Oncol
, vol.3
, pp. 402-408
-
-
White-Gilbertson, S.1
Kurtz, D.T.2
Voelkel-Johnson, C.3
-
23
-
-
33645531089
-
Elongation factor-2 kinase regulates autophagy in human glioblastoma cells
-
COI: 1:CAS:528:DC%2BD28Xitlersb8%3D, PID: 16540650
-
Wu H, Yang JM, Jin S et al (2006) Elongation factor-2 kinase regulates autophagy in human glioblastoma cells. Cancer Res 66:3015–3023
-
(2006)
Cancer Res
, vol.66
, pp. 3015-3023
-
-
Wu, H.1
Yang, J.M.2
Jin, S.3
-
24
-
-
55449127119
-
Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2
-
COI: 1:CAS:528:DC%2BD1cXhtlCgs7zM, PID: 18991566
-
Wullner U, Neef I, Eller A et al (2008) Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2. Curr Cancer Drug Targets 8:554–565
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 554-565
-
-
Wullner, U.1
Neef, I.2
Eller, A.3
-
25
-
-
84878970288
-
c-Jun-mediated anticancer mechanisms of tylophorine
-
COI: 1:CAS:528:DC%2BC3sXptFCnsLw%3D, PID: 23385061
-
Yang CW, Lee YZ, Hsu HY et al (2013) c-Jun-mediated anticancer mechanisms of tylophorine. Carcinogenesis 34:1304–1314
-
(2013)
Carcinogenesis
, vol.34
, pp. 1304-1314
-
-
Yang, C.W.1
Lee, Y.Z.2
Hsu, H.Y.3
-
26
-
-
34447522119
-
Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Kruppel-like factor 5
-
COI: 1:CAS:528:DC%2BD2sXltl2gu7w%3D, PID: 17430902
-
Zhang H, Bialkowska A, Rusovici R et al (2007) Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Kruppel-like factor 5. J Biol Chem 282:15541–15549
-
(2007)
J Biol Chem
, vol.282
, pp. 15541-15549
-
-
Zhang, H.1
Bialkowska, A.2
Rusovici, R.3
-
27
-
-
80054061981
-
Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression
-
COI: 1:CAS:528:DC%2BC3MXhtlaks7nJ, PID: 21945617
-
Zhang Y, Cheng Y, Zhang L et al (2011) Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression. Biochem Biophys Res Commun 414:129–134
-
(2011)
Biochem Biophys Res Commun
, vol.414
, pp. 129-134
-
-
Zhang, Y.1
Cheng, Y.2
Zhang, L.3
-
28
-
-
84905060749
-
Translational regulator eIF2α in tumor
-
COI: 1:CAS:528:DC%2BC2cXht1egurjE, PID: 24609900
-
Zheng Q, Ye J, Cao J (2014) Translational regulator eIF2α in tumor. Tumour Biol 35:6255–6264
-
(2014)
Tumour Biol
, vol.35
, pp. 6255-6264
-
-
Zheng, Q.1
Ye, J.2
Cao, J.3
|