Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism

Neuropsychopharmacology

Volumn 40, Issue 4, 2015, Pages 874-883

  Paumier, Katrina L ^a,b   Sortwell, Caryl E ^a,b   Madhavan, Lalitha ^a,c   Terpstra, Brian ^a,d   Celano, Stephanie L ^b   Green, Joshua J ^b   Imus, Nastassja M ^b   Marckini, Nathan ^b   Daley, Brian ^a,b   Steece Collier, Kathy ^a,b   Collier, Timothy J ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; TYROSINE 3 MONOOXYGENASE; ADRENERGIC RECEPTOR STIMULATING AGENT; ANALGESIC AGENT; OXIDOPAMINE; SACCHARIN;

ADULT; ANHEDONIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DOWN REGULATION; IMMUNOHISTOCHEMISTRY; LONG TERM CARE; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; RAT; STRIATONIGRAL DEGENERATION; SUBSTANTIA NIGRA PARS COMPACTA; TAIL SUSPENSION TEST; TREATMENT RESPONSE; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; FOOD PREFERENCE; GENE EXPRESSION REGULATION; IMMOBILIZATION; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOLOGY; PSYCHOMOTOR PERFORMANCE; SUBSTANTIA NIGRA; WISTAR RAT;

ADRENERGIC AGENTS; AMITRIPTYLINE; ANALGESICS, NON-NARCOTIC; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FOOD PREFERENCES; GENE EXPRESSION REGULATION; HINDLIMB SUSPENSION; MALE; NEURODEGENERATIVE DISEASES; OXIDOPAMINE; PARKINSONIAN DISORDERS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, WISTAR; SACCHARIN; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 84925533286     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.262     Document Type: Article

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