-
1
-
-
84925524502
-
-
www.cdc.gov/nchs/data/hus/hus10.pdf#fig17
-
-
-
-
2
-
-
26244432388
-
Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
-
COI: 1:CAS:528:DC%2BD2MXhtVOlu7fM, PID: 16214597
-
Baigent C, Keech A, Kearney PM et al (2005) Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366(9493):1267–1278
-
(2005)
Lancet
, vol.366
, Issue.9493
, pp. 1267-1278
-
-
Baigent, C.1
Keech, A.2
Kearney, P.M.3
-
3
-
-
0025120211
-
Regulation of the mevalonate pathway
-
COI: 1:CAS:528:DyaK3cXhtlCmtbw%3D, PID: 1967820
-
Goldstein JL, Brown MS (1990) Regulation of the mevalonate pathway. Nature 343(6257):425–430
-
(1990)
Nature
, vol.343
, Issue.6257
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
4
-
-
10644286120
-
Pleiotropic effects of statins
-
COI: 1:CAS:528:DC%2BD2MXisVWjtrY%3D, PID: 15822172
-
Liao JK, Laufs U (2005) Pleiotropic effects of statins. Annu Rev Pharmacol Toxicol 45:89–118
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 89-118
-
-
Liao, J.K.1
Laufs, U.2
-
5
-
-
0036322869
-
Isoprenoids as mediators of the biological effects of statins
-
COI: 1:CAS:528:DC%2BD38XlvFKht7c%3D, PID: 12163444
-
Liao JK (2002) Isoprenoids as mediators of the biological effects of statins. J Clin Invest 110(3):285–288
-
(2002)
J Clin Invest
, vol.110
, Issue.3
, pp. 285-288
-
-
Liao, J.K.1
-
6
-
-
0034930259
-
HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2
-
COI: 1:CAS:528:DC%2BD3MXlt1KltL4%3D, PID: 11408350
-
Wachtershauser A, Akoglu B, Stein J (2001) HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. Carcinogenesis 22(7):1061–1067
-
(2001)
Carcinogenesis
, vol.22
, Issue.7
, pp. 1061-1067
-
-
Wachtershauser, A.1
Akoglu, B.2
Stein, J.3
-
7
-
-
0036207642
-
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells
-
COI: 1:CAS:528:DC%2BD38Xis1Kntbs%3D, PID: 11895868
-
Agarwal B, Halmos B, Feoktistov AS et al (2002) Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells. Carcinogenesis 23(3):521–528
-
(2002)
Carcinogenesis
, vol.23
, Issue.3
, pp. 521-528
-
-
Agarwal, B.1
Halmos, B.2
Feoktistov, A.S.3
-
8
-
-
84858661389
-
Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression
-
COI: 1:CAS:528:DC%2BC38XlslKhsr4%3D, PID: 22134829
-
Spampanato C, De MS, Sarnataro M et al (2012) Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression. Int J Oncol 40(4):935–941
-
(2012)
Int J Oncol
, vol.40
, Issue.4
, pp. 935-941
-
-
Spampanato, C.1
De, M.S.2
Sarnataro, M.3
-
9
-
-
47049103366
-
Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice
-
COI: 1:CAS:528:DC%2BD1cXovFWmu7g%3D, PID: 18521906
-
Cho SJ, Kim JS, Kim JM, Lee JY, Jung HC, Song IS (2008) Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice. Int J Cancer 123(4):951–957
-
(2008)
Int J Cancer
, vol.123
, Issue.4
, pp. 951-957
-
-
Cho, S.J.1
Kim, J.S.2
Kim, J.M.3
Lee, J.Y.4
Jung, H.C.5
Song, I.S.6
-
10
-
-
33646949251
-
Statin use and breast cancer: prospective results from the women’s health initiative
-
COI: 1:CAS:528:DC%2BD28XkvVSrs7w%3D, PID: 16705124
-
Cauley JA, McTiernan A, Rodabough RJ et al (2006) Statin use and breast cancer: prospective results from the women’s health initiative. J Natl Cancer Inst 98(10):700–707
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.10
, pp. 700-707
-
-
Cauley, J.A.1
McTiernan, A.2
Rodabough, R.J.3
-
11
-
-
37449001291
-
Statin use and risk of breast cancer
-
PID: 18008366
-
Pocobelli G, Newcomb PA, Trentham-Dietz A, Titus-Ernstoff L, Hampton JM, Egan KM (2008) Statin use and risk of breast cancer. Cancer 112(1):27–33
-
(2008)
Cancer
, vol.112
, Issue.1
, pp. 27-33
-
-
Pocobelli, G.1
Newcomb, P.A.2
Trentham-Dietz, A.3
Titus-Ernstoff, L.4
Hampton, J.M.5
Egan, K.M.6
-
12
-
-
73449089467
-
Incidence of cancer and statin usage—record linkage study
-
COI: 1:CAS:528:DC%2BD1MXhsVamt7bE, PID: 19739258
-
Haukka J, Sankila R, Klaukka T et al (2010) Incidence of cancer and statin usage—record linkage study. Int J Cancer 126(1):279–284
-
(2010)
Int J Cancer
, vol.126
, Issue.1
, pp. 279-284
-
-
Haukka, J.1
Sankila, R.2
Klaukka, T.3
-
13
-
-
84886416119
-
Prospective analysis of association between statin use and breast cancer risk in the women’s health initiative
-
COI: 1:CAS:528:DC%2BC3sXhsFynsr%2FE, PID: 23975947
-
Desai P, Chlebowski R, Cauley JA et al (2013) Prospective analysis of association between statin use and breast cancer risk in the women’s health initiative. Cancer Epidemiol Biomarkers Prev 22(10):1868–1876
-
(2013)
Cancer Epidemiol Biomarkers Prev
, vol.22
, Issue.10
, pp. 1868-1876
-
-
Desai, P.1
Chlebowski, R.2
Cauley, J.A.3
-
14
-
-
52649098048
-
Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users
-
COI: 1:CAS:528:DC%2BD1cXmtVClsL4%3D
-
Kumar AS, Benz CC, Shim V, Minami CA, Moore DH, Esserman LJ (2008) Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users. Cancer Epidemiol Biomark Prev 17(5):1028–1033
-
(2008)
Cancer Epidemiol Biomark Prev
, vol.17
, Issue.5
, pp. 1028-1033
-
-
Kumar, A.S.1
Benz, C.C.2
Shim, V.3
Minami, C.A.4
Moore, D.H.5
Esserman, L.J.6
-
15
-
-
80054848246
-
Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins
-
COI: 1:CAS:528:DC%2BC3MXhtlGisbrF, PID: 21936625
-
Chae YK, Valsecchi ME, Kim J et al (2011) Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins. Cancer Invest 29(9):585–593
-
(2011)
Cancer Invest
, vol.29
, Issue.9
, pp. 585-593
-
-
Chae, Y.K.1
Valsecchi, M.E.2
Kim, J.3
-
16
-
-
43949103427
-
Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors
-
COI: 1:CAS:528:DC%2BD1cXlvVCgt74%3D, PID: 17674197
-
Kwan ML, Habel LA, Flick ED, Quesenberry CP, Caan B (2008) Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors. Breast Cancer Res Treat 109(3):573–579
-
(2008)
Breast Cancer Res Treat
, vol.109
, Issue.3
, pp. 573-579
-
-
Kwan, M.L.1
Habel, L.A.2
Flick, E.D.3
Quesenberry, C.P.4
Caan, B.5
-
17
-
-
80054078528
-
Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study
-
COI: 1:CAS:528:DC%2BC3MXht12rsrbJ, PID: 21813413
-
Ahern TP, Pedersen L, Tarp M et al (2011) Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study. J Natl Cancer Inst 103(19):1461–1468
-
(2011)
J Natl Cancer Inst
, vol.103
, Issue.19
, pp. 1461-1468
-
-
Ahern, T.P.1
Pedersen, L.2
Tarp, M.3
-
18
-
-
84884564996
-
Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort
-
COI: 1:CAS:528:DC%2BC3sXhsFKitL3O, PID: 24086446
-
Nickels S, Vrieling A, Seibold P et al (2013) Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort. PLoS ONE 8(9):e75088
-
(2013)
PLoS ONE
, vol.8
, Issue.9
, pp. 75088
-
-
Nickels, S.1
Vrieling, A.2
Seibold, P.3
-
19
-
-
84868550230
-
Statin use and reduced cancer-related mortality
-
COI: 1:CAS:528:DC%2BC38Xhs1ekt73N, PID: 23134381
-
Nielsen SF, Nordestgaard BG, Bojesen SE (2012) Statin use and reduced cancer-related mortality. N Engl J Med 367(19):1792–1802
-
(2012)
N Engl J Med
, vol.367
, Issue.19
, pp. 1792-1802
-
-
Nielsen, S.F.1
Nordestgaard, B.G.2
Bojesen, S.E.3
-
20
-
-
6844255857
-
The Women’s Health Initiative Study Group
-
Design of the Women’s Health Initiative clinical trial and observational study. The Women’s Health Initiative Study Group (1998) Control Clin Trials 19(1):61–109
-
(1998)
Control Clin Trials
, vol.19
, Issue.1
, pp. 61-109
-
-
-
21
-
-
10744219623
-
Implementation of the women’s health initiative study design
-
PID: 14575938
-
Anderson GL, Manson J, Wallace R et al (2003) Implementation of the women’s health initiative study design. Ann Epidemiol 13(9 Suppl):S5–17
-
(2003)
Ann Epidemiol
, vol.13
, pp. 5-17
-
-
Anderson, G.L.1
Manson, J.2
Wallace, R.3
-
22
-
-
0037125379
-
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s health initiative randomized controlled trial
-
COI: 1:CAS:528:DC%2BD38Xltlegs7k%3D, PID: 12117397
-
Rossouw JE, Anderson GL, Prentice RL et al (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s health initiative randomized controlled trial. JAMA 288(3):321–333
-
(2002)
JAMA
, vol.288
, Issue.3
, pp. 321-333
-
-
Rossouw, J.E.1
Anderson, G.L.2
Prentice, R.L.3
-
23
-
-
13444251203
-
Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update
-
COI: 1:CAS:528:DC%2BD2MXhsVCms7Y%3D, PID: 15660968
-
Schachter M (2005) Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol 19(1):117–125
-
(2005)
Fundam Clin Pharmacol
, vol.19
, Issue.1
, pp. 117-125
-
-
Schachter, M.1
-
24
-
-
84906093514
-
Statins in therapy: understanding their hydrophilicity, lipophilicity, binding to 3-hydroxy-3-methylglutaryl-CoA reductase, ability to cross the blood brain barrier and metabolic stability based on electrostatic molecular orbital studies
-
Fong CW (2014) Statins in therapy: understanding their hydrophilicity, lipophilicity, binding to 3-hydroxy-3-methylglutaryl-CoA reductase, ability to cross the blood brain barrier and metabolic stability based on electrostatic molecular orbital studies. Eur J Med Chem 85C:661–674
-
(2014)
Eur J Med Chem
, vol.85C
, pp. 661-674
-
-
Fong, C.W.1
-
25
-
-
10744233268
-
Outcomes ascertainment and adjudication methods in the women’s health initiative
-
PID: 14575944
-
Curb JD, McTiernan A, Heckbert SR et al (2003) Outcomes ascertainment and adjudication methods in the women’s health initiative. Ann Epidemiol 13(9 Suppl):S122–S128
-
(2003)
Ann Epidemiol
, vol.13
, pp. 122-128
-
-
Curb, J.D.1
McTiernan, A.2
Heckbert, S.R.3
-
26
-
-
1542532754
-
A proportional hazards model for the subdistribution of a competing risk
-
Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94(446):496–509
-
(1999)
J Am Stat Assoc
, vol.94
, Issue.446
, pp. 496-509
-
-
Fine, J.P.1
Gray, R.J.2
-
27
-
-
0037137175
-
Isoprenoids influence expression of Ras and Ras-related proteins
-
COI: 1:CAS:528:DC%2BD38XotFSqtro%3D, PID: 12427032
-
Holstein SA, Wohlford-Lenane CL, Hohl RJ (2002) Isoprenoids influence expression of Ras and Ras-related proteins. Biochemistry 41(46):13698–13704
-
(2002)
Biochemistry
, vol.41
, Issue.46
, pp. 13698-13704
-
-
Holstein, S.A.1
Wohlford-Lenane, C.L.2
Hohl, R.J.3
-
29
-
-
0032977036
-
Rho as a mediator of G protein-coupled receptor signaling
-
COI: 1:CAS:528:DyaK1MXjsVOks78%3D, PID: 10347235
-
Seasholtz TM, Majumdar M, Brown JH (1999) Rho as a mediator of G protein-coupled receptor signaling. Mol Pharmacol 55(6):949–956
-
(1999)
Mol Pharmacol
, vol.55
, Issue.6
, pp. 949-956
-
-
Seasholtz, T.M.1
Majumdar, M.2
Brown, J.H.3
-
30
-
-
0034908034
-
Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study
-
COI: 1:CAS:528:DC%2BD3MXlvVSqtbs%3D, PID: 11470741
-
Denoyelle C, Vasse M, Korner M et al (2001) Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study. Carcinogenesis 22(8):1139–1148
-
(2001)
Carcinogenesis
, vol.22
, Issue.8
, pp. 1139-1148
-
-
Denoyelle, C.1
Vasse, M.2
Korner, M.3
-
31
-
-
78049523865
-
Effect of statin therapy on colorectal cancer
-
COI: 1:CAS:528:DC%2BC3cXhsFemurjJ, PID: 20660702
-
Bardou M, Barkun A, Martel M (2010) Effect of statin therapy on colorectal cancer. Gut 59(11):1572–1585
-
(2010)
Gut
, vol.59
, Issue.11
, pp. 1572-1585
-
-
Bardou, M.1
Barkun, A.2
Martel, M.3
-
32
-
-
3142723163
-
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest
-
COI: 1:CAS:528:DC%2BD2cXkvV2ntbs%3D, PID: 15205608
-
Asakage M, Tsuno NH, Kitayama J et al (2004) 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest. Anticancer Drugs 15(6):625–632
-
(2004)
Anticancer Drugs
, vol.15
, Issue.6
, pp. 625-632
-
-
Asakage, M.1
Tsuno, N.H.2
Kitayama, J.3
-
33
-
-
0026039147
-
Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin
-
COI: 1:CAS:528:DyaK3MXksVWmsLY%3D, PID: 1711413
-
Keyomarsi K, Sandoval L, Band V, Pardee AB (1991) Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin. Cancer Res 51(13):3602–3609
-
(1991)
Cancer Res
, vol.51
, Issue.13
, pp. 3602-3609
-
-
Keyomarsi, K.1
Sandoval, L.2
Band, V.3
Pardee, A.B.4
-
34
-
-
0031784485
-
Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis
-
COI: 1:CAS:528:DyaK1cXntVylu7k%3D, PID: 9802623
-
Alonso DF, Farina HG, Skilton G, Gabri MR, De Lorenzo MS, Gomez DE (1998) Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis. Breast Cancer Res Treat 50(1):83–93
-
(1998)
Breast Cancer Res Treat
, vol.50
, Issue.1
, pp. 83-93
-
-
Alonso, D.F.1
Farina, H.G.2
Skilton, G.3
Gabri, M.R.4
De Lorenzo, M.S.5
Gomez, D.E.6
-
35
-
-
0036395370
-
Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells
-
COI: 1:CAS:528:DC%2BD38Xnt1agsLo%3D, PID: 12405293
-
Farina HG, Bublik DR, Alonso DF, Gomez DE (2002) Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells. Clin Exp Metastasis 19(6):551–559
-
(2002)
Clin Exp Metastasis
, vol.19
, Issue.6
, pp. 551-559
-
-
Farina, H.G.1
Bublik, D.R.2
Alonso, D.F.3
Gomez, D.E.4
-
36
-
-
0242363185
-
Lipid-lowering drug use and breast cancer in older women: a prospective study
-
Cauley JA, Zmuda JM, Lui LY et al (2003) Lipid-lowering drug use and breast cancer in older women: a prospective study. J Womens Health (Larchmt) 12(8):749–756
-
(2003)
J Womens Health (Larchmt)
, vol.12
, Issue.8
, pp. 749-756
-
-
Cauley, J.A.1
Zmuda, J.M.2
Lui, L.Y.3
-
37
-
-
2442687001
-
The association between 3-hydroxy-3-methylglutaryl coenzyme A inhibitor use and breast carcinoma risk among postmenopausal women: a case–control study
-
COI: 1:CAS:528:DC%2BD2cXltFWqu7k%3D, PID: 15160333
-
Boudreau DM, Gardner JS, Malone KE, Heckbert SR, Blough DK, Daling JR (2004) The association between 3-hydroxy-3-methylglutaryl coenzyme A inhibitor use and breast carcinoma risk among postmenopausal women: a case–control study. Cancer 100(11):2308–2316
-
(2004)
Cancer
, vol.100
, Issue.11
, pp. 2308-2316
-
-
Boudreau, D.M.1
Gardner, J.S.2
Malone, K.E.3
Heckbert, S.R.4
Blough, D.K.5
Daling, J.R.6
-
38
-
-
33644846806
-
Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies
-
PID: 16260694
-
Bonovas S, Filioussi K, Tsavaris N, Sitaras NM (2005) Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies. J Clin Oncol 23(34):8606–8612
-
(2005)
J Clin Oncol
, vol.23
, Issue.34
, pp. 8606-8612
-
-
Bonovas, S.1
Filioussi, K.2
Tsavaris, N.3
Sitaras, N.M.4
|