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Volumn 99, Issue 5, 2015, Pages 2243-2253

Engineering increased triacylglycerol accumulation in Saccharomyces cerevisiae using a modified type 1 plant diacylglycerol acyltransferase

Author keywords

Biofuel; Brassica napus; DGAT; Storage lipid synthesis; Yeast

Indexed keywords

BIOCHEMISTRY; BIOFUELS; CATALYSIS; ENZYME ACTIVITY; GENETIC ENGINEERING; GLYCEROL; LIPIDS; PLANTS (BOTANY); YEAST;

EID: 84925507673     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-6284-4     Document Type: Article
Times cited : (44)

References (43)
  • 1
    • 77950991763 scopus 로고    scopus 로고
    • Tobacco as a production platform for biofuel: overexpression of Arabidopsis DGAT and LEC2 genes increases accumulation and shifts the composition of lipids in green biomass
    • COI: 1:CAS:528:DC%2BC3cXks1Clu7w%3D, PID: 20051035
    • Andrianov V, Borisjuk N, Pogrebnyak N, Brinker A, Dixon J, Spitsin S, Flynn J, Matyszczuk P, Andryszak K, Laurelli M, Golovkin M, Koprowski H (2010) Tobacco as a production platform for biofuel: overexpression of Arabidopsis DGAT and LEC2 genes increases accumulation and shifts the composition of lipids in green biomass. Plant Biotechnol J 8(3):277–87. doi:10.1111/j.1467-7652.2009.00458.x
    • (2010) Plant Biotechnol J , vol.8 , Issue.3 , pp. 277-287
    • Andrianov, V.1    Borisjuk, N.2    Pogrebnyak, N.3    Brinker, A.4    Dixon, J.5    Spitsin, S.6    Flynn, J.7    Matyszczuk, P.8    Andryszak, K.9    Laurelli, M.10    Golovkin, M.11    Koprowski, H.12
  • 2
    • 0033971564 scopus 로고    scopus 로고
    • Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase
    • COI: 1:CAS:528:DC%2BD3cXlt1WktQ%3D%3D, PID: 10601854
    • Bouvier-Nave P, Benveniste P, Oelkers P, Sturley SL, Schaller H (2000) Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase. Eur J Biochem 267:85–96. doi:10.1046/j.1432-1327.2000.00961.x
    • (2000) Eur J Biochem , vol.267 , pp. 85-96
    • Bouvier-Nave, P.1    Benveniste, P.2    Oelkers, P.3    Sturley, S.L.4    Schaller, H.5
  • 3
    • 84925507910 scopus 로고    scopus 로고
    • BRAD
    • BRAD (2011) Brassica Database. http://brassicadb.org/brad/
    • (2011) Brassica Database
  • 4
    • 0032169575 scopus 로고    scopus 로고
    • Expression and properties of acyl-CoA binding protein from Brassica napus
    • COI: 1:CAS:528:DyaK1cXmvVyjtr0%3D
    • Brown AP, Johnson P, Rawsthorne S, Hills MJ (1998) Expression and properties of acyl-CoA binding protein from Brassica napus. Plant Physiol Biochem 36:629–635. doi:10.1016/S0981-9428(98)80011-9
    • (1998) Plant Physiol Biochem , vol.36 , pp. 629-635
    • Brown, A.P.1    Johnson, P.2    Rawsthorne, S.3    Hills, M.J.4
  • 5
    • 0032763186 scopus 로고    scopus 로고
    • Factors enhancing diacylglycerol acyltransferase activity in microsomes from cell-suspension cultures of oilseed rape
    • COI: 1:CAS:528:DyaK1MXnvFKmsLo%3D, PID: 10606036
    • Byers SD, Laroche A, Smith KC, Weselake RJ (1999) Factors enhancing diacylglycerol acyltransferase activity in microsomes from cell-suspension cultures of oilseed rape. Lipids 34:1143–1149. doi:10.1007/s11745-999-0465-6
    • (1999) Lipids , vol.34 , pp. 1143-1149
    • Byers, S.D.1    Laroche, A.2    Smith, K.C.3    Weselake, R.J.4
  • 7
    • 43549125523 scopus 로고    scopus 로고
    • Plant triacylglycerols as feedstocks for the production of biofuels
    • COI: 1:CAS:528:DC%2BD1cXmvFKgsr0%3D, PID: 18476866
    • Durrett TP, Benning C, Ohlrogge J (2008) Plant triacylglycerols as feedstocks for the production of biofuels. Plant J 54(4):593–607. doi:10.1111/j.1365-313X.2008.03442.x
    • (2008) Plant J , vol.54 , Issue.4 , pp. 593-607
    • Durrett, T.P.1    Benning, C.2    Ohlrogge, J.3
  • 8
    • 34347206860 scopus 로고    scopus 로고
    • High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
    • COI: 1:CAS:528:DC%2BD2sXhtFGntb%2FL
    • Gietz RD, Schiestl RH (2007) High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protocols 2(1):31–34. doi:10.1038/nprot.2007.13
    • (2007) Nat Protocols , vol.2 , Issue.1 , pp. 31-34
    • Gietz, R.D.1    Schiestl, R.H.2
  • 9
    • 0023663451 scopus 로고
    • Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs
    • COI: 1:CAS:528:DyaL2sXktFykt7o%3D, PID: 3554144
    • Hamilton R, Watanabe CK, de Boer HA (1987) Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs. Nucleic Acids Res 15(8):3581–3593. doi:10.1093/nar/15.8.3581
    • (1987) Nucleic Acids Res , vol.15 , Issue.8 , pp. 3581-3593
    • Hamilton, R.1    Watanabe, C.K.2    de Boer, H.A.3
  • 10
    • 36348956692 scopus 로고    scopus 로고
    • DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the ∆snf2 disruptant of Saccharomyces cerevisiae
    • COI: 1:CAS:528:DC%2BD2sXht1ahtLjI, PID: 17688423
    • Kamisaka Y, Tomita N, Kimura K, Kainou K, Uemura H (2007) DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the ∆snf2 disruptant of Saccharomyces cerevisiae. Biochem J 408(1):61–8. doi:10.1042/bj20070449
    • (2007) Biochem J , vol.408 , Issue.1 , pp. 61-68
    • Kamisaka, Y.1    Tomita, N.2    Kimura, K.3    Kainou, K.4    Uemura, H.5
  • 11
    • 77955852026 scopus 로고    scopus 로고
    • Activation of diacylglycerol acyltransferase expressed in Saccharomyces cerevisiae: overexpression of Dga1p lacking the N-terminal region in the ∆snf2 disruptant produces a significant increase in its enzyme activity
    • Kamisaka Y, Kimura K, Uemura H, Shibakami M (2010) Activation of diacylglycerol acyltransferase expressed in Saccharomyces cerevisiae: overexpression of Dga1p lacking the N-terminal region in the ∆snf2 disruptant produces a significant increase in its enzyme activity. Appl Microbiol Biotechnol 88(1):105–15. doi:10.1007/s00253-010-2725-x
    • (2010) Appl Microbiol Biotechnol , vol.88 , Issue.1 , pp. 105-115
    • Kamisaka, Y.1    Kimura, K.2    Uemura, H.3    Shibakami, M.4
  • 12
    • 84881227172 scopus 로고    scopus 로고
    • Overexpression of the active diacylglycerol acyltransferase variant transforms Saccharomyces cerevisiae into an oleaginous yeast
    • COI: 1:CAS:528:DC%2BC3sXhtFyjsbbK, PID: 23613035
    • Kamisaka Y, Kimura K, Uemura H, Yamaoka M (2013) Overexpression of the active diacylglycerol acyltransferase variant transforms Saccharomyces cerevisiae into an oleaginous yeast. Appl Microbiol Biotechnol 97(16):7345–55. doi:10.1007/s00253-013-4915-9
    • (2013) Appl Microbiol Biotechnol , vol.97 , Issue.16 , pp. 7345-7355
    • Kamisaka, Y.1    Kimura, K.2    Uemura, H.3    Yamaoka, M.4
  • 13
    • 18144385855 scopus 로고    scopus 로고
    • Dependence of biodiesel fuel properties on the structure of fatty acid alkyl esters
    • COI: 1:CAS:528:DC%2BD2MXjvVCkt7g%3D
    • Knothe G (2005) Dependence of biodiesel fuel properties on the structure of fatty acid alkyl esters. Fuel Process Technol 86(10):1059–1070. doi:10.1016/j.fuproc.2004.11.002
    • (2005) Fuel Process Technol , vol.86 , Issue.10 , pp. 1059-1070
    • Knothe, G.1
  • 14
    • 84855915589 scopus 로고    scopus 로고
    • Influence of feedstock: air pollution and climate-related emissions from a diesel generator operating on soybean, canola, and yellow grease biodiesel
    • Lackey LG, Paulson SE (2011) Influence of feedstock: air pollution and climate-related emissions from a diesel generator operating on soybean, canola, and yellow grease biodiesel. Energy Fuels 26(1):686–700. doi:10.1021/ef2011904
    • (2011) Energy Fuels , vol.26 , Issue.1 , pp. 686-700
    • Lackey, L.G.1    Paulson, S.E.2
  • 15
    • 51849105034 scopus 로고    scopus 로고
    • Perspectives of microbial oils for biodiesel production
    • COI: 1:CAS:528:DC%2BD1cXhtFWls7jE, PID: 18690426
    • Li Q, Du W, Liu D (2008) Perspectives of microbial oils for biodiesel production. Appl Microbiol Biotechnol 80(5):749–56. doi:10.1007/s00253-008-1625-9
    • (2008) Appl Microbiol Biotechnol , vol.80 , Issue.5 , pp. 749-756
    • Li, Q.1    Du, W.2    Liu, D.3
  • 16
    • 77949263134 scopus 로고    scopus 로고
    • DGAT1, DGAT2 and PDAT expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants
    • PID: 20101470
    • Li R, Yu K, Hildebrand D (2010) DGAT1, DGAT2 and PDAT expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants. Lipids 45(2):145–157. doi:10.1007/s11745-010-3385-4
    • (2010) Lipids , vol.45 , Issue.2 , pp. 145-157
    • Li, R.1    Yu, K.2    Hildebrand, D.3
  • 17
    • 84878305121 scopus 로고    scopus 로고
    • Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology
    • COI: 1:CAS:528:DC%2BC3sXhslGlsbfL, PID: 23685199
    • Liang MH, Jiang JG (2013) Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology. Prog Lipid Res 52(4):395–408. doi:10.1016/j.plipres.2013.05.002
    • (2013) Prog Lipid Res , vol.52 , Issue.4 , pp. 395-408
    • Liang, M.H.1    Jiang, J.G.2
  • 18
    • 33645544476 scopus 로고    scopus 로고
    • Genomic evolution of Brassica allopolyploids revealed by ISSR marker
    • COI: 1:CAS:528:DC%2BD28XlsFansbk%3D
    • Liu A-h, Wang J-b (2006) Genomic evolution of Brassica allopolyploids revealed by ISSR marker. Genet Resour Crop Evol 53(3):603–611. doi:10.1007/s10722-004-2951-0
    • (2006) Genet Resour Crop Evol , vol.53 , Issue.3 , pp. 603-611
    • Liu, A.-H.1    Wang, J.-B.2
  • 19
    • 79953858620 scopus 로고    scopus 로고
    • Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis
    • Liu Q, Siloto RMP, Snyder CL, Weselake RJ (2011) Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis. J Biol Chem. doi:10.1074/jbc.M110.204412
    • (2011) J Biol Chem
    • Liu, Q.1    Siloto, R.M.P.2    Snyder, C.L.3    Weselake, R.J.4
  • 20
    • 84863700580 scopus 로고    scopus 로고
    • Acyl-CoA:diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology
    • COI: 1:CAS:528:DC%2BC38XhtlamtrvN, PID: 22705711
    • Liu Q, Siloto RM, Lehner R, Stone SJ, Weselake RJ (2012) Acyl-CoA:diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology. Prog Lipid Res 51(4):350–77. doi:10.1016/j.plipres.2012.06.001
    • (2012) Prog Lipid Res , vol.51 , Issue.4 , pp. 350-377
    • Liu, Q.1    Siloto, R.M.2    Lehner, R.3    Stone, S.J.4    Weselake, R.J.5
  • 21
    • 33846211895 scopus 로고    scopus 로고
    • Diacylglycerol acyltransferase: a key mediator of plant triacylglycerol synthesis
    • COI: 1:CAS:528:DC%2BD2sXmvVyrsQ%3D%3D, PID: 17269553
    • Lung SC, Weselake R (2006) Diacylglycerol acyltransferase: a key mediator of plant triacylglycerol synthesis. Lipids 41(12):1073–1088
    • (2006) Lipids , vol.41 , Issue.12 , pp. 1073-1088
    • Lung, S.C.1    Weselake, R.2
  • 22
    • 78549270833 scopus 로고    scopus 로고
    • Topological orientation of acyl-CoA:diacylglycerol acyltransferase-1 (DGAT1) and identification of a putative active site histidine and the role of the N terminus in dimer/tetramer formation
    • COI: 1:CAS:528:DC%2BC3cXhsVCrt77J, PID: 20876538
    • Mcfie PJ, Stone SL, Banman SL, Stone SJ (2010) Topological orientation of acyl-CoA:diacylglycerol acyltransferase-1 (DGAT1) and identification of a putative active site histidine and the role of the N terminus in dimer/tetramer formation. J Biol Chem 285:37377–37387. doi:10.1074/jbc.M110.163691
    • (2010) J Biol Chem , vol.285 , pp. 37377-37387
    • Mcfie, P.J.1    Stone, S.L.2    Banman, S.L.3    Stone, S.J.4
  • 23
    • 0000394098 scopus 로고    scopus 로고
    • Isolation and sequence analysis of a novel cDNA encoding a putative diacylglycerol acyltransferase from a microspore-derived cell suspension culture of Brassica napus L. cv Jet Neuf
    • Nykiforuk CL, Laroche A, Weselake RJ (1999) Isolation and sequence analysis of a novel cDNA encoding a putative diacylglycerol acyltransferase from a microspore-derived cell suspension culture of Brassica napus L. cv Jet Neuf. Plant Physiol 120(1207):99–123
    • (1999) Plant Physiol , vol.120 , Issue.1207 , pp. 99-123
    • Nykiforuk, C.L.1    Laroche, A.2    Weselake, R.J.3
  • 24
    • 67349241722 scopus 로고    scopus 로고
    • Addition of an N-terminal epitope tag significantly increases the activity of plant fatty acid desaturases expressed in yeast cells
    • PID: 19137289
    • O’Quin JB, Mullen RT, Dyer JM (2009) Addition of an N-terminal epitope tag significantly increases the activity of plant fatty acid desaturases expressed in yeast cells. Appl Microbiol Biotechnol 83(1):117–25. doi:10.1007/s00253-008-1826-2
    • (2009) Appl Microbiol Biotechnol , vol.83 , Issue.1 , pp. 117-125
    • O’Quin, J.B.1    Mullen, R.T.2    Dyer, J.M.3
  • 25
    • 44849084901 scopus 로고    scopus 로고
    • Standardized gene nomenclature for the Brassica genus
    • PID: 18492252
    • Ostergaard L, King G (2008) Standardized gene nomenclature for the Brassica genus. Plant Methods 4(1):10. doi:10.1186/1746-4811-4-10
    • (2008) Plant Methods , vol.4 , Issue.1 , pp. 10
    • Ostergaard, L.1    King, G.2
  • 26
    • 84891829362 scopus 로고    scopus 로고
    • Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals
    • COI: 1:CAS:528:DC%2BC3sXht1altLnN, PID: 23899824
    • Runguphan W, Keasling JD (2014) Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals. Metab Eng 21:103–13. doi:10.1016/j.ymben.2013.07.003
    • (2014) Metab Eng , vol.21 , pp. 103-113
    • Runguphan, W.1    Keasling, J.D.2
  • 28
    • 84925500797 scopus 로고    scopus 로고
    • Agronomic performance, blackleg resistance and seed quality of doubled haploid lines of Brassica napus summer rape in Canada
    • Copenhagen: Denmark
    • Séguin-Swartz G, Gugel, R., Rakow, G., and Raney, J.P. Agronomic performance, blackleg resistance and seed quality of doubled haploid lines of Brassica napus summer rape in Canada. In: Proceedings of the 11th International Rapeseed Congress, Copenhagen, Denmark, 2003. p 452–454
    • (2003) Proceedings of the 11th International Rapeseed Congress , pp. 452-454
    • Séguin-Swartz, G.1    Gugel, R.2    Rakow, G.3    Raney, J.P.4
  • 29
    • 33749263895 scopus 로고    scopus 로고
    • Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum
    • COI: 1:CAS:528:DC%2BD28XhtVKgurbN, PID: 16920778
    • Shockey JM, Gidda SK, Chapital DC, Kuan J-C, Dhanoa PK, Bland JM, Rothsein SJ, Mullen RT, Dyer JM (2006) Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum. Plant Cell 18(9):2294–2313
    • (2006) Plant Cell , vol.18 , Issue.9 , pp. 2294-2313
    • Shockey, J.M.1    Gidda, S.K.2    Chapital, D.C.3    Kuan, J.-C.4    Dhanoa, P.K.5    Bland, J.M.6    Rothsein, S.J.7    Mullen, R.T.8    Dyer, J.M.9
  • 30
    • 47249093611 scopus 로고    scopus 로고
    • An N-terminal fragment of mouse DGAT1 binds different acyl-CoAs with varying affinity
    • COI: 1:CAS:528:DC%2BD1cXoslGmtbo%3D, PID: 18571500
    • Siloto RM, Madhavji M, Wiehler WB, Burton TL, Boora PS, Laroche A, Weselake RJ (2008) An N-terminal fragment of mouse DGAT1 binds different acyl-CoAs with varying affinity. Biochem Biophys Res Commun 373(3):350–354. doi:10.1016/j.bbrc.2008.06.031
    • (2008) Biochem Biophys Res Commun , vol.373 , Issue.3 , pp. 350-354
    • Siloto, R.M.1    Madhavji, M.2    Wiehler, W.B.3    Burton, T.L.4    Boora, P.S.5    Laroche, A.6    Weselake, R.J.7
  • 31
    • 70350247593 scopus 로고    scopus 로고
    • Simple methods to detect triacylglycerol biosynthesis in a yeast-based recombinant system
    • COI: 1:CAS:528:DC%2BD1MXht1OgtLvK, PID: 19763656
    • Siloto RM, Truksa M, He X, McKeon T, Weselake RJ (2009a) Simple methods to detect triacylglycerol biosynthesis in a yeast-based recombinant system. Lipids 44(10):963–973. doi:10.1007/s11745-009-3336-0
    • (2009) Lipids , vol.44 , Issue.10 , pp. 963-973
    • Siloto, R.M.1    Truksa, M.2    He, X.3    McKeon, T.4    Weselake, R.J.5
  • 32
    • 64749090067 scopus 로고    scopus 로고
    • Directed evolution of acyl-CoA:diacylglycerol acyltransferase: development and characterization of Brassica napus DGAT1 mutagenized libraries
    • COI: 1:CAS:528:DC%2BD1MXltFWlurw%3D, PID: 19195902
    • Siloto RMP, Truksa M, Brownfield D, Good AG, Weselake RJ (2009b) Directed evolution of acyl-CoA:diacylglycerol acyltransferase: development and characterization of Brassica napus DGAT1 mutagenized libraries. Plant Physiol Biochem 47(6):456–461. doi:10.1016/j.plaphy.2008.12.019
    • (2009) Plant Physiol Biochem , vol.47 , Issue.6 , pp. 456-461
    • Siloto, R.M.P.1    Truksa, M.2    Brownfield, D.3    Good, A.G.4    Weselake, R.J.5
  • 33
    • 80054958053 scopus 로고    scopus 로고
    • The N-end rule pathway: emerging functions and molecular principles of substrate recognition
    • COI: 1:CAS:528:DC%2BC3MXhtlGhtbjM, PID: 22016057
    • Sriram SM, Kim BY, Kwon YT (2011) The N-end rule pathway: emerging functions and molecular principles of substrate recognition. Nat Rev Mol Cell Biol 12(11):735–747. doi:10.1038/nrm3217
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.11 , pp. 735-747
    • Sriram, S.M.1    Kim, B.Y.2    Kwon, Y.T.3
  • 34
    • 0025242338 scopus 로고
    • The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene
    • COI: 1:CAS:528:DyaK3MXhvVGktg%3D%3D, PID: 1978720
    • Stukey JE, McDonough VM, Martin CE (1990) The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene. J Biol Chem 265(33):20144–9
    • (1990) J Biol Chem , vol.265 , Issue.33 , pp. 20144-20149
    • Stukey, J.E.1    McDonough, V.M.2    Martin, C.E.3
  • 35
    • 84870674137 scopus 로고    scopus 로고
    • Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production
    • COI: 1:CAS:528:DC%2BC3sXnvFWqtw%3D%3D, PID: 23026119
    • Tai M, Stephanopoulos G (2013) Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production. Metab Eng 15:1–9. doi:10.1016/j.ymben.2012.08.007
    • (2013) Metab Eng , vol.15 , pp. 1-9
    • Tai, M.1    Stephanopoulos, G.2
  • 36
    • 84874556188 scopus 로고    scopus 로고
    • Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae
    • COI: 1:CAS:528:DC%2BC3sXktFWitLg%3D, PID: 23353549
    • Tang X, Feng H, Chen WN (2013) Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae. Metab Eng 16(0):95–102. doi:10.1016/j.ymben.2013.01.003
    • (2013) Metab Eng , vol.16 , Issue.0 , pp. 95-102
    • Tang, X.1    Feng, H.2    Chen, W.N.3
  • 37
    • 84861210856 scopus 로고    scopus 로고
    • The N-end rule pathway
    • COI: 1:CAS:528:DC%2BC38XhtVGls7bL, PID: 22524314
    • Tasaki T, Sriram SM, Park KS, Kwon YT (2012) The N-end rule pathway. Annu Rev Biochem 81:261–89. doi:10.1146/annurev-biochem-051710-093308
    • (2012) Annu Rev Biochem , vol.81 , pp. 261-289
    • Tasaki, T.1    Sriram, S.M.2    Park, K.S.3    Kwon, Y.T.4
  • 39
    • 80053173840 scopus 로고    scopus 로고
    • Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis
    • COI: 1:CAS:528:DC%2BC3MXhtlamu7vN, PID: 21933415
    • Turchetto-Zolet AC, Maraschin FS, de Morais GL, Cagliari A, Andrade CM, Margis-Pinheiro M, Margis R (2011) Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis. BMC Evol Biol 11:263. doi:10.1186/1471-2148-11-263
    • (2011) BMC Evol Biol , vol.11 , pp. 263
    • Turchetto-Zolet, A.C.1    Maraschin, F.S.2    de Morais, G.L.3    Cagliari, A.4    Andrade, C.M.5    Margis-Pinheiro, M.6    Margis, R.7
  • 41
    • 39549083453 scopus 로고    scopus 로고
    • Cloning and functional analysis of two type 1 diacylglycerol acyltransferases from Vernonia galamensis
    • COI: 1:CAS:528:DC%2BD1cXitlKjtLk%3D, PID: 18179805
    • Yu K, Li R, Hatanaka T, Hildebrand D (2008) Cloning and functional analysis of two type 1 diacylglycerol acyltransferases from Vernonia galamensis. Phytochemistry 69(5):1119–27. doi:10.1016/j.phytochem.2007.11.015
    • (2008) Phytochemistry , vol.69 , Issue.5 , pp. 1119-1127
    • Yu, K.1    Li, R.2    Hatanaka, T.3    Hildebrand, D.4
  • 42
    • 84869880091 scopus 로고    scopus 로고
    • Development of a Saccharomyces cerevisiae strain for increasing the accumulation of triacylglycerol as a microbial oil feedstock for biodiesel production using glycerol as a substrate
    • COI: 1:CAS:528:DC%2BC38Xht1Sku77J, PID: 22886471
    • Yu KO, Jung J, Ramzi AB, Choe SH, Kim SW, Park C, Han SO (2013) Development of a Saccharomyces cerevisiae strain for increasing the accumulation of triacylglycerol as a microbial oil feedstock for biodiesel production using glycerol as a substrate. Biotechnol Bioeng 110(1):343–7. doi:10.1002/bit.24623
    • (2013) Biotechnol Bioeng , vol.110 , Issue.1 , pp. 343-347
    • Yu, K.O.1    Jung, J.2    Ramzi, A.B.3    Choe, S.H.4    Kim, S.W.5    Park, C.6    Han, S.O.7
  • 43
    • 84882424024 scopus 로고    scopus 로고
    • A thraustochytrid diacylglycerol acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds
    • Zhang C, Iskandarov U, Klotz ET, Stevens RL, Cahoon RE, Nazarenus TJ, Pereira SL, Cahoon EB (2013) A thraustochytrid diacylglycerol acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds. J Exp Bot. doi:10.1093/jxb/ert156
    • (2013) J Exp Bot
    • Zhang, C.1    Iskandarov, U.2    Klotz, E.T.3    Stevens, R.L.4    Cahoon, R.E.5    Nazarenus, T.J.6    Pereira, S.L.7    Cahoon, E.B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.