A suicidal zinc finger nuclease expression coupled with a surrogate reporter for efficient genome engineering

Biotechnology Letters

Volumn 37, Issue 2, 2015, Pages 299-305

  Zhang, Cunfang ^a,b   Xu, Kun ^a   Hu, Linyong ^b   Wang, Ling ^a,c   Zhang, Tingting ^a   Ren, Chonghua ^a   Zhang, Zhiying ^a  

^a NORTHWEST A F UNIVERSITY   (China)

^b NORTHWEST INSTITUTE OF PLATEAU BIOLOGY   (China)

^c SHAANXI UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Cytotoxicity; Double strand breaks; Gene targeting; Homologous recombination; Off targeting; Zinc finger nuclease

Indexed keywords

CYTOTOXICITY; TOXICITY; ZINC;

DOUBLE STRAND BREAKS; GENE TARGETING; HOMOLOGOUS RECOMBINATION; OFF-TARGETING; ZINC FINGER NUCLEASE;

GENES;

DEOXYRIBONUCLEASE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; ZINC FINGER PROTEIN;

CELL SURVIVAL; GENETIC ENGINEERING; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; REPORTER GENE;

BASE SEQUENCE; CELL SURVIVAL; DEOXYRIBONUCLEASES; GENES, REPORTER; GENETIC ENGINEERING; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; ZINC FINGERS;

EID: 84925491894     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1690-3     Document Type: Article

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