Effects of antioxidant gene therapy on the development of diabetic retinopathy and the metabolic memory phenomenon

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 253, Issue 2, 2015, Pages 249-259

  Zhang, Liwei ^a   Xia, Huiming ^b   Han, Qianqian ^a   Chen, Baihua ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Diabetic retinopathy; Manganese superoxide dismutase; Metabolic memory; Reactive oxygen species

Indexed keywords

CATALASE; MANGANESE SUPEROXIDE DISMUTASE; PARVOVIRUS VECTOR; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; SUPEROXIDE DISMUTASE;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; CAPILLARY BASEMENT MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC RETINOPATHY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENE TARGETING; GENE THERAPY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; MALE; METABOLIC MEMORY; METABOLIC PARAMETERS; NERVE FIBER; NONHUMAN; PERICYTE; PRIORITY JOURNAL; RAT; RETINA CAPILLARY; THERAPY EFFECT; THICKNESS; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; ANIMAL; BASEMENT MEMBRANE; CAPILLARY; DEPENDOPARVOVIRUS; DIABETES MELLITUS, EXPERIMENTAL; ENZYMOLOGY; GENE VECTOR; GENETICS; INTRAVITREAL DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; RETINA BLOOD VESSEL; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BASEMENT MEMBRANE; CAPILLARIES; CATALASE; DEPENDOVIRUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC THERAPY; GENETIC VECTORS; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTRAVITREAL INJECTIONS; MALE; METABOLIC PHENOMENA; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; RATS, SPRAGUE-DAWLEY; RETINAL VESSELS; SUPEROXIDE DISMUTASE;

EID: 84925489119     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-014-2827-8     Document Type: Article

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