Amphiphilic Cationic Nanogels as Brain-Targeted Carriers for Activated Nucleoside Reverse Transcriptase Inhibitors

Journal of Neuroimmune Pharmacology

Volumn 10, Issue 1, 2015, Pages 88-101

  Warren, G ^a   Makarov, E ^a   Lu, Y ^a   Senanayake, T ^a   Rivera, K ^a   Gorantla, S ^a   Poluektova, L Y ^a   Vinogradov, S V ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Abacavir; Blood brain barrier; Brain specific peptides; Central nervous system; HIV 1; Lamivudine; Nanogels; Neurotoxicity; NRTI 5 triphosphates; Nucleoside reverse transcriptase inhibitors; Zidovudine; polylysine

Indexed keywords

ABACAVIR; EPSILON POLYLYSINE; LAMIVUDINE; NANOCARRIER; POLYLYSINE; UNCLASSIFIED DRUG; ZIDOVUDINE; CATION; CHOLESTEROL; DRUG CARRIER; GEL; NANOMATERIAL; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ANIMAL CELL; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; CARCINOMA CELL; CELL TRANSPORT; CIRCULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; MACROPHAGE; MICROGLIA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; NERVE CELL; NEUROTOXICITY; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; BRAIN; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GEL; HUMAN IMMUNODEFICIENCY VIRUS 1; MITOCHONDRION;

APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN; CATIONS; CELL LINE; CELL SURVIVAL; CHOLESTEROL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GELS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MITOCHONDRIA; NANOSTRUCTURES; NEURONS; POLYLYSINE; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 84925488612     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-014-9576-7     Document Type: Article

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