F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation

Biochemical and Biophysical Research Communications

Volumn 458, Issue 4, 2015, Pages 941-945

  Li, Dongnian ^a   Xie, Ping ^b   Zhao, Fei ^c   Shu, Jingyi ^b   Li, Li ^a   Zhan, Yutao ^a   Zhang, Lingqiang ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c PEKING UNIVERSITY SHOUGANG HOSPITAL   (China)

Author keywords

Fbxo3; Proteasomal degradation; Protein ubiquitination; Smurf1; Ubiquitin ligase

Indexed keywords

F BOX PROTEIN; FBXO3 PROTEIN; SMURF1 PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; BONE MORPHOGENETIC PROTEIN; FBX3 PROTEIN, HUMAN; PROTEASOME; SMURF1 PROTEIN, HUMAN;

ARTICLE; EMBRYO; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN TARGETING; UBIQUITINATION; METABOLISM; PROTEIN PROTEIN INTERACTION;

BONE MORPHOGENETIC PROTEINS; F-BOX PROTEINS; HEK293 CELLS; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPS; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84925484790     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.089     Document Type: Article

References (20)

1. A. Hershko, and A. Ciechanover The ubiquitin system Annu Rev. Biochem. 67 1998 425 479
2. D. Rotin, and S. Kumar Physiological functions of the HECT family of ubiquitin ligases Nat. Rev. Mol. Cell. Biol. 10 2009 398 409
3. H. Zhu, P. Kavsak, S. Abdollah, J.L. Wrana, and G.H. Thomsen A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Nature 400 1999 687 693
4. M. Yamashita, S.X. Ying, G.M. Zhang, C. Li, S.Y. Cheng, C.X. Deng, and Y.E. Zhang Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation Cell 121 2005 101 113
5. M. Narimatsu, R. Bose, M. Pye, L. Zhang, B. Miller, P. Ching, R. Sakuma, V. Luga, L. Roncari, L. Attisano, and J.L. Wrana Regulation of planar cell polarity by Smurf ubiquitin ligases Cell 137 2009 295 307
6. H.R. Wang, Y. Zhang, B. Ozdamar, A.A. Ogunjimi, E. Alexandrova, G.H. Thomsen, and J.L. Wrana Regulation of cell polarity and protrusion formation by targeting RhoA for degradation Science 302 2003 1775 1779
7. K. Lu, X. Yin, T. Weng, S. Xi, L. Li, G. Xing, X. Cheng, X. Yang, L. Zhang, and F. He Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1 Nat. Cell. Biol. 10 2008 994 1002
8. P. Xie, M. Zhang, S. He, K. Lu, Y. Chen, G. Xing, Y. Lu, P. Liu, Y. Li, S. Wang, N. Chai, J. Wu, H. Deng, H. Wang, Y. Cao, F. Zhao, Y. Cui, J. Wang, F. He, and L. Zhang Covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis Nat. Commun. 13 2014 3733
9. E. Fukunaga, Y. Inoue, S. Komiya, K. Horiguchi, K. Goto, M. Saitoh, K. Miyazawa, D. Koinuma, A. Hanyu, and T. Imamura Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells J. Biol. Chem. 283 2008 35660 35667
10. Y. Cui, S. He, C. Xing, K. Lu, J. Wang, G. Xing, A. Meng, S. Jia, F. He, and L. Zhang SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 EMBO J. 30 2011 2675 2689
11. J. Jin, T. Cardozo, R.C. Lovering, S.J. Elledge, M. Pagano, and J.W. Harper Systematic analysis and nomenclature of mammalian F-box proteins Genes. Dev. 18 2004 2573 2580
12. R.K. Mallampalli, T.A. Coon, J.R. Glasser, C. Wang, S.R. Dunn, N.M. Weathington, J. Zhao, C. Zou, Y. Zhao, and B.B. Chen Targeting F box protein Fbxo3 to control cytokine-driven inflammation J. Immunol. 191 2013 5247 5255
13. B.B. Chen, T.A. Coon, J.R. Glasser, B.J. McVerry, J. Zhao, Y. Zhao, C. Zou, B. Ellis, F.C. Sciurba, Y. Zhang, and R.K. Mallampalli A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation Nat. Immunol. 14 2013 470 479
14. Y. Shima, T. Shima, T. Chiba, T. Irimura, P.P. Pandolfi, and I. Kitabayashi PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation Mol. Cell. Biol. 28 2008 7126 7138
15. P. Xie, Y. Tang, S. Shen, Y. Wang, G. Xing, Y. Yin, F. He, and L. Zhang Smurf1 ubiquitin ligase targets Kruppel-like factor KLF2 for ubiquitination and degradation in human lung cancer H1299 cell Biochem. Biophys. Res. Commun. 407 2011 254 259
16. Y. Cao, C. Wang, X. Zhang, G. Xing, K. Lu, Y. Gu, F. He, and L. Zhang Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5degradation Sci. Rep. 4 2014 4965
17. A. Magnifico, S. Ettenberg, C. Yang, J. Mariano, S. Tiwari, S. Fang, S. Lipkowitz, and A.M. Weissman WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation J. Biol. Chem. 278 2003 43,169 43,177
18. V. Subramaniam, H. Li, M. Wong, R. Kitching, L. Attisano, J. Wrana, J. Zubovits, A.M. Burger, and A. Seth The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase Br. J. Cancer 89 2003 1538 1544
19. J.R. Skaar, V. D'Angiolella, J.K. Pagan, and M. Pagano SnapShot: F-box proteins II Cell 137 2009 1358
20. J.R. Skaar, J.K. Pagan, and M. Pagano SnapShot: F box proteins I Cell 137 2009 1160