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Volumn 58, Issue 4, 2015, Pages 666-677

The effects of capillary dysfunction on oxygen and glucose extraction in diabetic neuropathy

Author keywords

Capillary dysfunction; Diabetic complications; Diabetic neuropathy; Glucose intolerance; Glucose transport; Microvascular disease

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALDEHYDE REDUCTASE; GLUCOSE; OXYGEN; GLUCOSE BLOOD LEVEL;

EID: 84925467087     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3461-z     Document Type: Review
Times cited : (60)

References (106)
  • 2
  • 3
    • 84856201567 scopus 로고    scopus 로고
    • Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
    • PID: 22271716
    • Tesfaye S, Selvarajah D (2012) Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy. Diabetes Metab Res Rev 28(Suppl 1):8–14
    • (2012) Diabetes Metab Res Rev , vol.28 , pp. 8-14
    • Tesfaye, S.1    Selvarajah, D.2
  • 4
    • 0028928433 scopus 로고
    • Basement membrane reduplication and pericyte degeneration precede development of diabetic polyneuropathy and are associated with its severity
    • COI: 1:STN:280:DyaK2M3jtlOgtA%3D%3D, PID: 7717686
    • Giannini C, Dyck PJ (1995) Basement membrane reduplication and pericyte degeneration precede development of diabetic polyneuropathy and are associated with its severity. Ann Neurol 37:498–504
    • (1995) Ann Neurol , vol.37 , pp. 498-504
    • Giannini, C.1    Dyck, P.J.2
  • 5
    • 0141755309 scopus 로고    scopus 로고
    • Endoneurial capillary abnormalities presage deterioration of glucose tolerance and accompany peripheral neuropathy in man
    • COI: 1:CAS:528:DC%2BD3sXotVWhsbg%3D, PID: 14514647
    • Thrainsdottir S, Malik RA, Dahlin LB et al (2003) Endoneurial capillary abnormalities presage deterioration of glucose tolerance and accompany peripheral neuropathy in man. Diabetes 52:2615–2622
    • (2003) Diabetes , vol.52 , pp. 2615-2622
    • Thrainsdottir, S.1    Malik, R.A.2    Dahlin, L.B.3
  • 6
    • 0035195970 scopus 로고    scopus 로고
    • Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD38XisFGmtg%3D%3D, PID: 11719828
    • Cameron NE, Eaton SE, Cotter MA, Tesfaye S (2001) Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 44:1973–1988
    • (2001) Diabetologia , vol.44 , pp. 1973-1988
    • Cameron, N.E.1    Eaton, S.E.2    Cotter, M.A.3    Tesfaye, S.4
  • 7
    • 0021145258 scopus 로고
    • Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy
    • PID: 6478183
    • Tuck RR, Schmelzer JD, Low PA (1984) Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy. Brain 107:935–950
    • (1984) Brain , vol.107 , pp. 935-950
    • Tuck, R.R.1    Schmelzer, J.D.2    Low, P.A.3
  • 8
    • 0028123578 scopus 로고
    • Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulin-dependent) diabetes mellitus
    • COI: 1:STN:280:DyaK2c3hsFOnuw%3D%3D, PID: 8163058
    • Jaap AJ, Hammersley MS, Shore AC, Tooke JE (1994) Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 37:214–216
    • (1994) Diabetologia , vol.37 , pp. 214-216
    • Jaap, A.J.1    Hammersley, M.S.2    Shore, A.C.3    Tooke, J.E.4
  • 9
    • 0027400644 scopus 로고
    • Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation
    • COI: 1:CAS:528:DyaK3sXhtFKmsb0%3D, PID: 7678825
    • Tilton RG, Chang K, Hasan KS et al (1993) Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation. Diabetes 42:221–232
    • (1993) Diabetes , vol.42 , pp. 221-232
    • Tilton, R.G.1    Chang, K.2    Hasan, K.S.3
  • 10
    • 0028966139 scopus 로고
    • Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats
    • COI: 1:CAS:528:DyaK2MXjtlCksLc%3D, PID: 7859946
    • Tilton RG, Chang K, Nyengaard JR, van den Enden M, Ido Y, Williamson JR (1995) Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats. Diabetes 44:234–242
    • (1995) Diabetes , vol.44 , pp. 234-242
    • Tilton, R.G.1    Chang, K.2    Nyengaard, J.R.3    van den Enden, M.4    Ido, Y.5    Williamson, J.R.6
  • 11
    • 0030852213 scopus 로고    scopus 로고
    • Local human sural nerve blood flow in diabetic and other polyneuropathies
    • PID: 9236626
    • Theriault M, Dort J, Sutherland G, Zochodne DW (1997) Local human sural nerve blood flow in diabetic and other polyneuropathies. Brain 120:1131–1138
    • (1997) Brain , vol.120 , pp. 1131-1138
    • Theriault, M.1    Dort, J.2    Sutherland, G.3    Zochodne, D.W.4
  • 13
    • 84856460295 scopus 로고    scopus 로고
    • The roles of cerebral blood flow, capillary transit time heterogeneity and oxygen tension in brain oxygenation and metabolism
    • COI: 1:CAS:528:DC%2BC38XhslOks7g%3D, PID: 22044867
    • Jespersen SN, Østergaard L (2012) The roles of cerebral blood flow, capillary transit time heterogeneity and oxygen tension in brain oxygenation and metabolism. J Cereb Blood Flow Metab 32:264–277
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 264-277
    • Jespersen, S.N.1    Østergaard, L.2
  • 14
    • 84884755163 scopus 로고    scopus 로고
    • The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis
    • PID: 23764543
    • Østergaard L, Tietze A, Nielsen T et al (2013) The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis. Cancer Res 73:5618–5624
    • (2013) Cancer Res , vol.73 , pp. 5618-5624
    • Østergaard, L.1    Tietze, A.2    Nielsen, T.3
  • 15
    • 84872343218 scopus 로고    scopus 로고
    • The capillary dysfunction hypothesis of Alzheimer's disease
    • PID: 23084084
    • Østergaard L, Aamand R, Gutierrez-Jimenez E et al (2013) The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiol Aging 34:1018–1031
    • (2013) Neurobiol Aging , vol.34 , pp. 1018-1031
    • Østergaard, L.1    Aamand, R.2    Gutierrez-Jimenez, E.3
  • 16
    • 0024814465 scopus 로고
    • Nerve blood flow and oxygen delivery in normal, diabetic, and ischemic neuropathy
    • COI: 1:STN:280:DyaK3c%2FptlOgtw%3D%3D, PID: 2557297
    • Low PA, Lagerlund TD, McManis PG (1989) Nerve blood flow and oxygen delivery in normal, diabetic, and ischemic neuropathy. Int Rev Neurobiol 31:355–438
    • (1989) Int Rev Neurobiol , vol.31 , pp. 355-438
    • Low, P.A.1    Lagerlund, T.D.2    McManis, P.G.3
  • 17
    • 0034570447 scopus 로고    scopus 로고
    • Slowing of motor nerve conduction velocity in streptozotocin-induced diabetic rats is preceded by impaired vasodilation in arterioles that overlie the sciatic nerve
    • COI: 1:STN:280:DC%2BD3MvhvFKqug%3D%3D, PID: 11469397
    • Coppey LJ, Davidson EP, Dunlap JA, Lund DD, Yorek MA (2000) Slowing of motor nerve conduction velocity in streptozotocin-induced diabetic rats is preceded by impaired vasodilation in arterioles that overlie the sciatic nerve. Int J Exp Diabetes Res 1:131–143
    • (2000) Int J Exp Diabetes Res , vol.1 , pp. 131-143
    • Coppey, L.J.1    Davidson, E.P.2    Dunlap, J.A.3    Lund, D.D.4    Yorek, M.A.5
  • 18
    • 0026722871 scopus 로고
    • Normal blood flow but lower oxygen tension in diabetes of young rats: microenvironment and the influence of sympathectomy
    • COI: 1:STN:280:DyaK3s%2FksFOktA%3D%3D, PID: 1423007
    • Zochodne DW, Ho LT (1992) Normal blood flow but lower oxygen tension in diabetes of young rats: microenvironment and the influence of sympathectomy. Can J Physiol Pharmacol 70:651–659
    • (1992) Can J Physiol Pharmacol , vol.70 , pp. 651-659
    • Zochodne, D.W.1    Ho, L.T.2
  • 19
    • 37149032566 scopus 로고    scopus 로고
    • Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats
    • COI: 1:CAS:528:DC%2BD2sXhsVGls7vP, PID: 17911342
    • Obrosova IG, Drel VR, Oltman CL et al (2007) Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats. Am J Physiol Endocrinol Metab 293:E1645–E1655
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. 1645-1655
    • Obrosova, I.G.1    Drel, V.R.2    Oltman, C.L.3
  • 20
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • COI: 1:CAS:528:DC%2BD1MXhtVKhs7%2FK, PID: 19718040
    • Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, Dalkara T (2009) Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med 15:1031–1037
    • (2009) Nat Med , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3    Can, A.4    Topalkara, K.5    Dalkara, T.6
  • 21
    • 0028222205 scopus 로고
    • Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway
    • COI: 1:STN:280:DyaK2c7ntFGgsw%3D%3D, PID: 7907321
    • Haefliger IO, Zschauer A, Anderson DR (1994) Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway. Invest Ophthalmol Vis Sci 35:991–997
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 991-997
    • Haefliger, I.O.1    Zschauer, A.2    Anderson, D.R.3
  • 22
    • 0028207046 scopus 로고
    • Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats
    • COI: 1:CAS:528:DyaK2cXltVGrsr4%3D, PID: 8056181
    • Cameron NE, Cotter MA, Archibald V, Dines KC, Maxfield EK (1994) Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia 37:449–459
    • (1994) Diabetologia , vol.37 , pp. 449-459
    • Cameron, N.E.1    Cotter, M.A.2    Archibald, V.3    Dines, K.C.4    Maxfield, E.K.5
  • 23
    • 0035430412 scopus 로고    scopus 로고
    • Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve
    • COI: 1:CAS:528:DC%2BD3MXlslKms74%3D, PID: 11473057
    • Coppey LJ, Gellett JS, Davidson EP, Dunlap JA, Lund DD, Yorek MA (2001) Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50:1927–1937
    • (2001) Diabetes , vol.50 , pp. 1927-1937
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Lund, D.D.5    Yorek, M.A.6
  • 24
    • 0027494924 scopus 로고
    • Impaired blood flow and arterio-venous shunting in human diabetic neuropathy: a novel technique of nerve photography and fluorescein angiography
    • COI: 1:STN:280:DyaK2c7ktVSjuw%3D%3D, PID: 8307254
    • Tesfaye S, Harris N, Jakubowski JJ et al (1993) Impaired blood flow and arterio-venous shunting in human diabetic neuropathy: a novel technique of nerve photography and fluorescein angiography. Diabetologia 36:1266–1274
    • (1993) Diabetologia , vol.36 , pp. 1266-1274
    • Tesfaye, S.1    Harris, N.2    Jakubowski, J.J.3
  • 25
    • 79951829343 scopus 로고    scopus 로고
    • Hypoxia and inflammation
    • COI: 1:CAS:528:DC%2BC3MXitFykt78%3D, PID: 21323543
    • Eltzschig HK, Carmeliet P (2011) Hypoxia and inflammation. N Engl J Med 364:656–665
    • (2011) N Engl J Med , vol.364 , pp. 656-665
    • Eltzschig, H.K.1    Carmeliet, P.2
  • 26
    • 42449157139 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD1cXksVGku74%3D, PID: 18039814
    • Toth C, Rong LL, Yang C et al (2008) Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy. Diabetes 57:1002–1017
    • (2008) Diabetes , vol.57 , pp. 1002-1017
    • Toth, C.1    Rong, L.L.2    Yang, C.3
  • 27
    • 84916620102 scopus 로고    scopus 로고
    • Soluble CD163 levels are elevated in cerebrospinal fluid and serum in people with type 2 diabetes mellitus and are associated with impaired peripheral nerve function
    • PID: 25156085
    • Kallestrup M, Moller HJ, Tankisi H, Andersen H (2014) Soluble CD163 levels are elevated in cerebrospinal fluid and serum in people with type 2 diabetes mellitus and are associated with impaired peripheral nerve function. Diabet Med. doi:10.1111/dme.12568
    • (2014) Diabet Med
    • Kallestrup, M.1    Moller, H.J.2    Tankisi, H.3    Andersen, H.4
  • 28
    • 79960697192 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia
    • COI: 1:CAS:528:DC%2BC3MXhtVKksrvO, PID: 21302291
    • Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, Prabhakar NR (2011) Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol 226:2925–2933
    • (2011) J Cell Physiol , vol.226 , pp. 2925-2933
    • Yuan, G.1    Khan, S.A.2    Luo, W.3    Nanduri, J.4    Semenza, G.L.5    Prabhakar, N.R.6
  • 29
    • 33746086028 scopus 로고    scopus 로고
    • Diabetic neuropathy and oxidative stress
    • COI: 1:CAS:528:DC%2BD28Xot1amur0%3D, PID: 16506271
    • Pop-Busui R, Sima A, Stevens M (2006) Diabetic neuropathy and oxidative stress. Diabetes Metab Res Rev 22:257–273
    • (2006) Diabetes Metab Res Rev , vol.22 , pp. 257-273
    • Pop-Busui, R.1    Sima, A.2    Stevens, M.3
  • 30
    • 34547593167 scopus 로고    scopus 로고
    • Microvascular tissue plasminogen activator is reduced in diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD2sXnsVChur0%3D, PID: 17636064
    • Hafer-Macko CE, Ivey FM, Sorkin JD, Macko RF (2007) Microvascular tissue plasminogen activator is reduced in diabetic neuropathy. Neurology 69:268–274
    • (2007) Neurology , vol.69 , pp. 268-274
    • Hafer-Macko, C.E.1    Ivey, F.M.2    Sorkin, J.D.3    Macko, R.F.4
  • 31
    • 20044370999 scopus 로고    scopus 로고
    • ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin
    • COI: 1:CAS:528:DC%2BD2MXlt1ynsrs%3D, PID: 15930396
    • Teng HK, Teng KK, Lee R et al (2005) ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 25:5455–5463
    • (2005) J Neurosci , vol.25 , pp. 5455-5463
    • Teng, H.K.1    Teng, K.K.2    Lee, R.3
  • 32
    • 70349928563 scopus 로고    scopus 로고
    • Expression of neurotrophic factors in diabetic muscle–relation to neuropathy and muscle strength
    • COI: 1:STN:280:DC%2BD1MnnslKrtg%3D%3D, PID: 19696031
    • Andreassen CS, Jakobsen J, Flyvbjerg A, Andersen H (2009) Expression of neurotrophic factors in diabetic muscle–relation to neuropathy and muscle strength. Brain 132:2724–2733
    • (2009) Brain , vol.132 , pp. 2724-2733
    • Andreassen, C.S.1    Jakobsen, J.2    Flyvbjerg, A.3    Andersen, H.4
  • 33
    • 42449100783 scopus 로고    scopus 로고
    • Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes
    • COI: 1:CAS:528:DC%2BD1cXksVGktbY%3D, PID: 18285558
    • Ali TK, Matragoon S, Pillai BA, Liou GI, El-Remessy AB (2008) Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes. Diabetes 57:889–898
    • (2008) Diabetes , vol.57 , pp. 889-898
    • Ali, T.K.1    Matragoon, S.2    Pillai, B.A.3    Liou, G.I.4    El-Remessy, A.B.5
  • 34
    • 84936765097 scopus 로고    scopus 로고
    • Peripheral nerve injury modulates neurotrophin signaling in the peripheral and central nervous system
    • COI: 1:CAS:528:DC%2BC2cXmsFartLk%3D, PID: 24752592
    • Richner M, Ulrichsen M, Elmegaard SL, Dieu R, Pallesen LT, Vaegter CB (2014) Peripheral nerve injury modulates neurotrophin signaling in the peripheral and central nervous system. Mol Neurobiol 50:945–970
    • (2014) Mol Neurobiol , vol.50 , pp. 945-970
    • Richner, M.1    Ulrichsen, M.2    Elmegaard, S.L.3    Dieu, R.4    Pallesen, L.T.5    Vaegter, C.B.6
  • 35
    • 0033060677 scopus 로고    scopus 로고
    • A new minimally invasive technique to show nerve ischaemia in diabetic neuropathy
    • COI: 1:CAS:528:DyaK1MXktFSisrk%3D, PID: 10382594
    • Ibrahim S, Harris ND, Radatz M et al (1999) A new minimally invasive technique to show nerve ischaemia in diabetic neuropathy. Diabetologia 42:737–742
    • (1999) Diabetologia , vol.42 , pp. 737-742
    • Ibrahim, S.1    Harris, N.D.2    Radatz, M.3
  • 36
    • 0026471588 scopus 로고
    • Correlations between nerve function and tissue oxygenation in diabetic patients: further clues to the aetiology of diabetic neuropathy?
    • COI: 1:STN:280:DyaK3s7it1ektg%3D%3D, PID: 1478366
    • Young MJ, Veves A, Walker MG, Boulton AJ (1992) Correlations between nerve function and tissue oxygenation in diabetic patients: further clues to the aetiology of diabetic neuropathy? Diabetologia 35:1146–1150
    • (1992) Diabetologia , vol.35 , pp. 1146-1150
    • Young, M.J.1    Veves, A.2    Walker, M.G.3    Boulton, A.J.4
  • 37
    • 0030065230 scopus 로고    scopus 로고
    • Arterio-venous shunting and proliferating new vessels in acute painful neuropathy of rapid glycaemic control (insulin neuritis)
    • COI: 1:STN:280:DyaK28zmtF2gsQ%3D%3D, PID: 8721779
    • Tesfaye S, Malik R, Harris N et al (1996) Arterio-venous shunting and proliferating new vessels in acute painful neuropathy of rapid glycaemic control (insulin neuritis). Diabetologia 39:329–335
    • (1996) Diabetologia , vol.39 , pp. 329-335
    • Tesfaye, S.1    Malik, R.2    Harris, N.3
  • 38
    • 25444463573 scopus 로고    scopus 로고
    • Endothelial/pericyte interactions
    • COI: 1:CAS:528:DC%2BD2MXpvFGrtLg%3D, PID: 16166562
    • Armulik A, Abramsson A, Betsholtz C (2005) Endothelial/pericyte interactions. Circ Res 97:512–523
    • (2005) Circ Res , vol.97 , pp. 512-523
    • Armulik, A.1    Abramsson, A.2    Betsholtz, C.3
  • 39
    • 0018715625 scopus 로고
    • In vitro studies of the substrates for energy production and the effects of insulin on glucose utilization in the neural components of peripheral nerve
    • COI: 1:CAS:528:DyaL3cXlt1CmsA%3D%3D, PID: 478182
    • Greene DA, Winegrad AI (1979) In vitro studies of the substrates for energy production and the effects of insulin on glucose utilization in the neural components of peripheral nerve. Diabetes 28:878–887
    • (1979) Diabetes , vol.28 , pp. 878-887
    • Greene, D.A.1    Winegrad, A.I.2
  • 40
    • 0024391941 scopus 로고
    • Structural specificity of sugar transport at the blood-nerve barrier
    • COI: 1:CAS:528:DyaL1MXksFCltb8%3D, PID: 2498463
    • Rechthand E, Smith QR, Rapoport SI (1989) Structural specificity of sugar transport at the blood-nerve barrier. J Neurochem 53:119–123
    • (1989) J Neurochem , vol.53 , pp. 119-123
    • Rechthand, E.1    Smith, Q.R.2    Rapoport, S.I.3
  • 41
    • 0027498070 scopus 로고
    • Expression of glucose transporter 1 in adult and developing human peripheral nerve
    • COI: 1:CAS:528:DyaK3sXitlSqsL4%3D, PID: 7681417
    • Muona P, Jaakkola S, Salonen V, Peltonen J (1993) Expression of glucose transporter 1 in adult and developing human peripheral nerve. Diabetologia 36:133–140
    • (1993) Diabetologia , vol.36 , pp. 133-140
    • Muona, P.1    Jaakkola, S.2    Salonen, V.3    Peltonen, J.4
  • 42
    • 0025057936 scopus 로고
    • Kinetic analysis of blood-brain barrier transport of d-glucose in man: quantitative evaluation in the presence of tracer backflux and capillary heterogeneity
    • COI: 1:CAS:528:DyaK3cXhsFGksL4%3D, PID: 2314306
    • Knudsen GM, Pettigrew KD, Paulson OB, Hertz MM, Patlak CS (1990) Kinetic analysis of blood-brain barrier transport of d-glucose in man: quantitative evaluation in the presence of tracer backflux and capillary heterogeneity. Microvasc Res 39:28–49
    • (1990) Microvasc Res , vol.39 , pp. 28-49
    • Knudsen, G.M.1    Pettigrew, K.D.2    Paulson, O.B.3    Hertz, M.M.4    Patlak, C.S.5
  • 43
    • 0026545543 scopus 로고
    • Increased permeability across the blood-nerve barrier of albumin glycated in vitro and in vivo from patients with diabetic polyneuropathy
    • COI: 1:CAS:528:DyaK38XitFahsbc%3D, PID: 1549585
    • Poduslo JF, Curran GL (1992) Increased permeability across the blood-nerve barrier of albumin glycated in vitro and in vivo from patients with diabetic polyneuropathy. Proc Natl Acad Sci U S A 89:2218–2222
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 2218-2222
    • Poduslo, J.F.1    Curran, G.L.2
  • 44
    • 0031026509 scopus 로고    scopus 로고
    • Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats
    • COI: 1:CAS:528:DyaK2sXhs1Ckt7k%3D, PID: 9084964
    • Cameron NE, Cotter MA, Basso M, Hohman TC (1997) Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats. Diabetologia 40:271–281
    • (1997) Diabetologia , vol.40 , pp. 271-281
    • Cameron, N.E.1    Cotter, M.A.2    Basso, M.3    Hohman, T.C.4
  • 45
    • 0032858197 scopus 로고    scopus 로고
    • Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study
    • COI: 1:CAS:528:DyaK1MXmt1ymtrk%3D, PID: 10525658
    • Obrosova IG, Fathallah L, Lang HJ, Greene DA (1999) Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study. Diabetologia 42:1187–1194
    • (1999) Diabetologia , vol.42 , pp. 1187-1194
    • Obrosova, I.G.1    Fathallah, L.2    Lang, H.J.3    Greene, D.A.4
  • 46
    • 14844296509 scopus 로고    scopus 로고
    • A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin-induced diabetes
    • COI: 1:CAS:528:DC%2BD2MXhvF2msLo%3D, PID: 15755558
    • Schmidt RE, Dorsey DA, Beaudet LN et al (2005) A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin-induced diabetes. Exp Neurol 192:407–419
    • (2005) Exp Neurol , vol.192 , pp. 407-419
    • Schmidt, R.E.1    Dorsey, D.A.2    Beaudet, L.N.3
  • 47
    • 84888640023 scopus 로고    scopus 로고
    • Pathogenesis of diabetic neuropathy: focus on neurovascular mechanisms
    • COI: 1:STN:280:DC%2BC3sfitlOiug%3D%3D, PID: 23872412
    • Sytze van Dam P, Cotter MA, Bravenboer B, Cameron NE (2013) Pathogenesis of diabetic neuropathy: focus on neurovascular mechanisms. Eur J Pharmacol 719:180–186
    • (2013) Eur J Pharmacol , vol.719 , pp. 180-186
    • Sytze van Dam, P.1    Cotter, M.A.2    Bravenboer, B.3    Cameron, N.E.4
  • 48
    • 33746456027 scopus 로고    scopus 로고
    • Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial
    • COI: 1:CAS:528:DC%2BD28XnsVahurw%3D, PID: 16801576
    • Hotta N, Akanuma Y, Kawamori R et al (2006) Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care 29:1538–1544
    • (2006) Diabetes Care , vol.29 , pp. 1538-1544
    • Hotta, N.1    Akanuma, Y.2    Kawamori, R.3
  • 49
    • 67650076664 scopus 로고    scopus 로고
    • Ranirestat for the management of diabetic sensorimotor polyneuropathy
    • COI: 1:CAS:528:DC%2BD1MXps1Kqsbo%3D, PID: 19366965
    • Bril V, Hirose T, Tomioka S, Buchanan R, Ranirestat Study Group (2009) Ranirestat for the management of diabetic sensorimotor polyneuropathy. Diabetes Care 32:1256–1260
    • (2009) Diabetes Care , vol.32 , pp. 1256-1260
    • Bril, V.1    Hirose, T.2    Tomioka, S.3    Buchanan, R.4    Ranirestat Study Group5
  • 50
    • 33745311155 scopus 로고    scopus 로고
    • Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes
    • COI: 1:CAS:528:DC%2BD28XjsVGmtbc%3D, PID: 16567538
    • Nieuwdorp M, Mooij HL, Kroon J et al (2006) Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes. Diabetes 55:1127–1132
    • (2006) Diabetes , vol.55 , pp. 1127-1132
    • Nieuwdorp, M.1    Mooij, H.L.2    Kroon, J.3
  • 51
    • 0034603747 scopus 로고    scopus 로고
    • Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-endothelial cell adhesion
    • COI: 1:CAS:528:DC%2BD3cXivVyhsbo%3D, PID: 10747340
    • Vink H, Constantinescu AA, Spaan JA (2000) Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-endothelial cell adhesion. Circulation 101:1500–1502
    • (2000) Circulation , vol.101 , pp. 1500-1502
    • Vink, H.1    Constantinescu, A.A.2    Spaan, J.A.3
  • 52
    • 0034975472 scopus 로고    scopus 로고
    • Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL
    • COI: 1:CAS:528:DC%2BD3MXjtV2gt7o%3D, PID: 11179046
    • Constantinescu AA, Vink H, Spaan JA (2001) Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL. Am J Physiol Heart Circ Physiol 280:H1051–H1057
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. 1051-1057
    • Constantinescu, A.A.1    Vink, H.2    Spaan, J.A.3
  • 53
    • 0029797605 scopus 로고    scopus 로고
    • Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries
    • COI: 1:CAS:528:DyaK28XlsVOns78%3D, PID: 8781491
    • Vink H, Duling BR (1996) Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries. Circ Res 79:581–589
    • (1996) Circ Res , vol.79 , pp. 581-589
    • Vink, H.1    Duling, B.R.2
  • 54
    • 33750856804 scopus 로고    scopus 로고
    • A model for red blood cell motion in glycocalyx-lined capillaries
    • COI: 1:CAS:528:DyaK1cXhvF2qtbc%3D, PID: 9530216
    • Secomb TW, Hsu R, Pries AR (1998) A model for red blood cell motion in glycocalyx-lined capillaries. Am J Physiol 274:H1016–H1022
    • (1998) Am J Physiol , vol.274 , pp. 1016-1022
    • Secomb, T.W.1    Hsu, R.2    Pries, A.R.3
  • 56
    • 33646010041 scopus 로고    scopus 로고
    • Roles for NF-κB in nerve cell survival, plasticity, and disease
    • COI: 1:CAS:528:DC%2BD28XjsFWisLc%3D, PID: 16397579
    • Mattson MP, Meffert MK (2006) Roles for NF-κB in nerve cell survival, plasticity, and disease. Cell Death Differ 13:852–860
    • (2006) Cell Death Differ , vol.13 , pp. 852-860
    • Mattson, M.P.1    Meffert, M.K.2
  • 57
    • 1242296820 scopus 로고    scopus 로고
    • Specific inhibition of IκB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats
    • COI: 1:CAS:528:DC%2BD2cXhvVCgu74%3D, PID: 14973242
    • Tegeder I, Niederberger E, Schmidt R et al (2004) Specific inhibition of IκB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats. J Neurosci 24:1637–1645
    • (2004) J Neurosci , vol.24 , pp. 1637-1645
    • Tegeder, I.1    Niederberger, E.2    Schmidt, R.3
  • 58
    • 58149335418 scopus 로고    scopus 로고
    • Sulfasalazine blocks the development of tactile allodynia in diabetic rats
    • COI: 1:CAS:528:DC%2BD1MXhs1Knt7s%3D, PID: 18633115
    • Berti-Mattera LN, Kern TS, Siegel RE, Nemet I, Mitchell R (2008) Sulfasalazine blocks the development of tactile allodynia in diabetic rats. Diabetes 57:2801–2808
    • (2008) Diabetes , vol.57 , pp. 2801-2808
    • Berti-Mattera, L.N.1    Kern, T.S.2    Siegel, R.E.3    Nemet, I.4    Mitchell, R.5
  • 59
    • 84908141553 scopus 로고    scopus 로고
    • Capillary dysfunction and impaired tissue oxygenation in complex regional pain syndrome: a hypothesis
    • PID: 24946228
    • Østergaard L, Terkelsen AJ, Finnerup NB et al (2014) Capillary dysfunction and impaired tissue oxygenation in complex regional pain syndrome: a hypothesis. Pain 155:1922–1926
    • (2014) Pain , vol.155 , pp. 1922-1926
    • Østergaard, L.1    Terkelsen, A.J.2    Finnerup, N.B.3
  • 60
    • 0020564688 scopus 로고
    • Sympathetic nerve failure in diabetes
    • COI: 1:STN:280:DyaL2c%2FivFKgsw%3D%3D, PID: 6628876
    • Watkins PJ, Edmonds ME (1983) Sympathetic nerve failure in diabetes. Diabetologia 25:73–77
    • (1983) Diabetologia , vol.25 , pp. 73-77
    • Watkins, P.J.1    Edmonds, M.E.2
  • 61
    • 84890887128 scopus 로고    scopus 로고
    • Diabetic foot cellular hypoxia may be due to capillary shunting–a novel hypothesis
    • PID: 24280559
    • Gabbay IE, Gabbay M, Gabbay U (2014) Diabetic foot cellular hypoxia may be due to capillary shunting–a novel hypothesis. Med Hypotheses 82:57–59
    • (2014) Med Hypotheses , vol.82 , pp. 57-59
    • Gabbay, I.E.1    Gabbay, M.2    Gabbay, U.3
  • 62
    • 0021715825 scopus 로고
    • Blood flow patterns in painful diabetic neuropathy
    • COI: 1:STN:280:DyaL2M7lsFSgtA%3D%3D, PID: 6530051
    • Archer AG, Roberts VC, Watkins PJ (1984) Blood flow patterns in painful diabetic neuropathy. Diabetologia 27:563–567
    • (1984) Diabetologia , vol.27 , pp. 563-567
    • Archer, A.G.1    Roberts, V.C.2    Watkins, P.J.3
  • 63
    • 34250214922 scopus 로고    scopus 로고
    • Loss of insulin-mediated vasoprotection: early effect of diabetes on pericyte-containing microvessels of the retina
    • PID: 17460301
    • Kobayashi T, Puro DG (2007) Loss of insulin-mediated vasoprotection: early effect of diabetes on pericyte-containing microvessels of the retina. Invest Ophthalmol Vis Sci 48:2350–2355
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 2350-2355
    • Kobayashi, T.1    Puro, D.G.2
  • 64
    • 70449108112 scopus 로고    scopus 로고
    • Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
    • COI: 1:CAS:528:DC%2BD1MXhtlers7nK, PID: 19881493
    • Geraldes P, Hiraoka-Yamamoto J, Matsumoto M et al (2009) Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med 15:1298–1306
    • (2009) Nat Med , vol.15 , pp. 1298-1306
    • Geraldes, P.1    Hiraoka-Yamamoto, J.2    Matsumoto, M.3
  • 65
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • COI: 1:CAS:528:DC%2BD28XhtVGkurrP, PID: 17036005
    • Peppiatt CM, Howarth C, Mobbs P, Attwell D (2006) Bidirectional control of CNS capillary diameter by pericytes. Nature 443:700–704
    • (2006) Nature , vol.443 , pp. 700-704
    • Peppiatt, C.M.1    Howarth, C.2    Mobbs, P.3    Attwell, D.4
  • 66
    • 84897564199 scopus 로고    scopus 로고
    • Capillary pericytes regulate cerebral blood flow in health and disease
    • COI: 1:CAS:528:DC%2BC2cXlsFyis7k%3D, PID: 24670647
    • Hall CN, Reynell C, Gesslein B et al (2014) Capillary pericytes regulate cerebral blood flow in health and disease. Nature 508:55–60
    • (2014) Nature , vol.508 , pp. 55-60
    • Hall, C.N.1    Reynell, C.2    Gesslein, B.3
  • 67
    • 0141535361 scopus 로고    scopus 로고
    • ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina
    • COI: 1:CAS:528:DC%2BD3sXosFOhsr0%3D, PID: 12876212
    • Kawamura H, Sugiyama T, Wu DM et al (2003) ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina. J Physiol 551:787–799
    • (2003) J Physiol , vol.551 , pp. 787-799
    • Kawamura, H.1    Sugiyama, T.2    Wu, D.M.3
  • 68
    • 33645730887 scopus 로고    scopus 로고
    • Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature
    • COI: 1:CAS:528:DC%2BD28XjtFCgsb0%3D, PID: 16299264
    • Yamanishi S, Katsumura K, Kobayashi T, Puro DG (2006) Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature. Am J Physiol Heart Circ Physiol 290:H925–H934
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. 925-934
    • Yamanishi, S.1    Katsumura, K.2    Kobayashi, T.3    Puro, D.G.4
  • 69
    • 33847256978 scopus 로고    scopus 로고
    • Physiology and pathobiology of the pericyte-containing retinal microvasculature: new developments
    • COI: 1:CAS:528:DC%2BD2sXis1ynu78%3D, PID: 17365657
    • Puro DG (2007) Physiology and pathobiology of the pericyte-containing retinal microvasculature: new developments. Microcirculation 14:1–10
    • (2007) Microcirculation , vol.14 , pp. 1-10
    • Puro, D.G.1
  • 70
    • 0014335044 scopus 로고
    • Studies of muscle capillary basement membranes in normal subjects, diabetic, and prediabetic patients
    • COI: 1:STN:280:DyaF1cvgsVKltA%3D%3D, PID: 5675423
    • Siperstein MD, Unger RH, Madison LL (1968) Studies of muscle capillary basement membranes in normal subjects, diabetic, and prediabetic patients. J Clin Invest 47:1973–1999
    • (1968) J Clin Invest , vol.47 , pp. 1973-1999
    • Siperstein, M.D.1    Unger, R.H.2    Madison, L.L.3
  • 71
    • 34250537223 scopus 로고
    • Pathological changes in the central and peripheral nervous system of young long-term diabetics: I. Diabetic encephalopathy
    • COI: 1:STN:280:DC%2BC2c7ht1yhsA%3D%3D, PID: 24173307
    • Reske-Nielsen E, Lundbaek K, Rafaelsen OJ (1966) Pathological changes in the central and peripheral nervous system of young long-term diabetics: I. Diabetic encephalopathy. Diabetologia 1:233–241
    • (1966) Diabetologia , vol.1 , pp. 233-241
    • Reske-Nielsen, E.1    Lundbaek, K.2    Rafaelsen, O.J.3
  • 73
    • 11344256587 scopus 로고    scopus 로고
    • Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina
    • COI: 1:CAS:528:DC%2BD2MXjtVaqtQ%3D%3D, PID: 15486015
    • Kawamura H, Kobayashi M, Li Q et al (2004) Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina. J Physiol 561:671–683
    • (2004) J Physiol , vol.561 , pp. 671-683
    • Kawamura, H.1    Kobayashi, M.2    Li, Q.3
  • 74
    • 0345698791 scopus 로고    scopus 로고
    • In situ observation of living pericytes in rat retinal capillaries
    • COI: 1:STN:280:DyaK1czltVWksw%3D%3D, PID: 9683560
    • Schonfelder U, Hofer A, Paul M, Funk RH (1998) In situ observation of living pericytes in rat retinal capillaries. Microvasc Res 56:22–29
    • (1998) Microvasc Res , vol.56 , pp. 22-29
    • Schonfelder, U.1    Hofer, A.2    Paul, M.3    Funk, R.H.4
  • 75
    • 68849128539 scopus 로고    scopus 로고
    • Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche
    • COI: 1:CAS:528:DC%2BD1MXhtVahsr3P, PID: 19475537
    • Diaz-Flores L, Gutierrez R, Madrid JF et al (2009) Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche. Histol Histopathol 24:909–969
    • (2009) Histol Histopathol , vol.24 , pp. 909-969
    • Diaz-Flores, L.1    Gutierrez, R.2    Madrid, J.F.3
  • 76
    • 38849162730 scopus 로고    scopus 로고
    • The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
    • COI: 1:CAS:528:DC%2BD1cXhs1Khsrw%3D, PID: 18167491
    • Lundberg JO, Weitzberg E, Gladwin MT (2008) The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 7:156–167
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 156-167
    • Lundberg, J.O.1    Weitzberg, E.2    Gladwin, M.T.3
  • 77
    • 77956518751 scopus 로고    scopus 로고
    • Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis
    • PID: 20724400
    • Carter P, Gray LJ, Troughton J, Khunti K, Davies MJ (2010) Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ 341:c4229
    • (2010) BMJ , vol.341 , pp. 4229
    • Carter, P.1    Gray, L.J.2    Troughton, J.3    Khunti, K.4    Davies, M.J.5
  • 78
    • 0036781580 scopus 로고    scopus 로고
    • Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study
    • COI: 1:CAS:528:DC%2BD38Xos1Whtro%3D, PID: 12351464
    • Yuen KC, Baker NR, Rayman G (2002) Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study. Diabetes Care 25:1699–1703
    • (2002) Diabetes Care , vol.25 , pp. 1699-1703
    • Yuen, K.C.1    Baker, N.R.2    Rayman, G.3
  • 79
    • 0032570130 scopus 로고    scopus 로고
    • Effect of angiotensin-converting-enzyme (ACE) inhibitor trandolapril on human diabetic neuropathy: randomised double-blind controlled trial
    • COI: 1:CAS:528:DyaK1MXktlOjsg%3D%3D, PID: 9872248
    • Malik RA, Williamson S, Abbott C et al (1998) Effect of angiotensin-converting-enzyme (ACE) inhibitor trandolapril on human diabetic neuropathy: randomised double-blind controlled trial. Lancet 352:1978–1981
    • (1998) Lancet , vol.352 , pp. 1978-1981
    • Malik, R.A.1    Williamson, S.2    Abbott, C.3
  • 80
    • 33644785987 scopus 로고    scopus 로고
    • ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy in streptozotocin-induced diabetic rats
    • COI: 1:CAS:528:DC%2BD28XhsFajsrk%3D, PID: 16443766
    • Coppey LJ, Davidson EP, Rinehart TW et al (2006) ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy in streptozotocin-induced diabetic rats. Diabetes 55:341–348
    • (2006) Diabetes , vol.55 , pp. 341-348
    • Coppey, L.J.1    Davidson, E.P.2    Rinehart, T.W.3
  • 81
    • 0346146974 scopus 로고    scopus 로고
    • Nerve conduction velocity and evoked potential latencies in streptozotocin-diabetic rats: effects of treatment with an angiotensin converting enzyme inhibitor
    • COI: 1:CAS:528:DC%2BD2cXis12jsw%3D%3D, PID: 14648806
    • Manschot SM, Gispen WH, Kappelle LJ, Biessels GJ (2003) Nerve conduction velocity and evoked potential latencies in streptozotocin-diabetic rats: effects of treatment with an angiotensin converting enzyme inhibitor. Diabetes Metab Res Rev 19:469–477
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 469-477
    • Manschot, S.M.1    Gispen, W.H.2    Kappelle, L.J.3    Biessels, G.J.4
  • 82
    • 0027435674 scopus 로고
    • Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat
    • COI: 1:CAS:528:DyaK2cXmvFWntw%3D%3D, PID: 8119324
    • Kappelle AC, Biessels GJ, van Buren T, Erkelens DW, de Wildt DJ, Gispen WH (1993) Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat. Eur J Pharmacol 250:43–49
    • (1993) Eur J Pharmacol , vol.250 , pp. 43-49
    • Kappelle, A.C.1    Biessels, G.J.2    van Buren, T.3    Erkelens, D.W.4    de Wildt, D.J.5    Gispen, W.H.6
  • 83
    • 0028182301 scopus 로고
    • 2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat
    • COI: 1:CAS:528:DyaK2cXitlGrt7k%3D, PID: 8019766
    • 2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat. Br J Pharmacol 111:887–893
    • (1994) Br J Pharmacol , vol.111 , pp. 887-893
    • Kappelle, A.C.1    Biessels, G.2    Bravenboer, B.3
  • 84
    • 84892425163 scopus 로고    scopus 로고
    • Neuropathy and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    • DCCT/EDIC Research Group, COI: 1:CAS:528:DC%2BC2cXjt1yrtbw%3D, PID: 24356595
    • Martin CL, Albers JW, Pop-Busui R, DCCT/EDIC Research Group (2014) Neuropathy and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care 37:31–38
    • (2014) Diabetes Care , vol.37 , pp. 31-38
    • Martin, C.L.1    Albers, J.W.2    Pop-Busui, R.3
  • 85
    • 0344146618 scopus 로고    scopus 로고
    • Capillary changes in skeletal muscle of patients with essential hypertension
    • COI: 1:STN:280:DC%2BD3c%2FlslKntg%3D%3D, PID: 10589028
    • Hernandez N, Torres SH, Finol HJ, Vera O (1999) Capillary changes in skeletal muscle of patients with essential hypertension. Anat Rec 256:425–432
    • (1999) Anat Rec , vol.256 , pp. 425-432
    • Hernandez, N.1    Torres, S.H.2    Finol, H.J.3    Vera, O.4
  • 86
    • 84893678906 scopus 로고    scopus 로고
    • Adipose tissue angiogenesis: impact on obesity and type-2 diabetes
    • COI: 1:CAS:528:DC%2BC3sXhtVyqtr7K, PID: 23770388
    • Corvera S, Gealekman O (2014) Adipose tissue angiogenesis: impact on obesity and type-2 diabetes. Biochim Biophys Acta 1842:463–472
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 463-472
    • Corvera, S.1    Gealekman, O.2
  • 87
    • 84906675768 scopus 로고    scopus 로고
    • Corneal confocal microscopy detects neuropathy in subjects with impaired glucose tolerance
    • COI: 1:CAS:528:DC%2BC2cXhslCqur%2FL, PID: 24969581
    • Asghar O, Petropoulos IN, Alam U et al (2014) Corneal confocal microscopy detects neuropathy in subjects with impaired glucose tolerance. Diabetes Care 37:2643–2646
    • (2014) Diabetes Care , vol.37 , pp. 2643-2646
    • Asghar, O.1    Petropoulos, I.N.2    Alam, U.3
  • 88
    • 84903216018 scopus 로고    scopus 로고
    • Early detection of nerve fiber loss by corneal confocal microscopy and skin biopsy in recently diagnosed type 2 diabetes
    • PID: 24574045
    • Ziegler D, Papanas N, Zhivov A et al (2014) Early detection of nerve fiber loss by corneal confocal microscopy and skin biopsy in recently diagnosed type 2 diabetes. Diabetes 63:2454–2463
    • (2014) Diabetes , vol.63 , pp. 2454-2463
    • Ziegler, D.1    Papanas, N.2    Zhivov, A.3
  • 89
    • 78651313012 scopus 로고    scopus 로고
    • The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension
    • COI: 1:CAS:528:DC%2BC3MXhslWns7o%3D, PID: 20971763
    • Capone C, Faraco G, Park L, Cao X, Davisson RL, Iadecola C (2011) The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. Am J Physiol Heart Circ Physiol 300:H397–H407
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. 397-407
    • Capone, C.1    Faraco, G.2    Park, L.3    Cao, X.4    Davisson, R.L.5    Iadecola, C.6
  • 90
    • 0030271233 scopus 로고    scopus 로고
    • Mechanisms and consequences of cell activation in the microcirculation
    • COI: 1:STN:280:DyaK2s%2Fnt1ChsQ%3D%3D, PID: 8915189
    • Mazzoni MC, Schmid-Schonbein GW (1996) Mechanisms and consequences of cell activation in the microcirculation. Cardiovasc Res 32:709–719
    • (1996) Cardiovasc Res , vol.32 , pp. 709-719
    • Mazzoni, M.C.1    Schmid-Schonbein, G.W.2
  • 91
    • 0017738994 scopus 로고
    • Is hyperviscosity a treatable component of diabetic microcirculatory disease?
    • COI: 1:STN:280:DyaE1c%2FgvFChtg%3D%3D, PID: 71601
    • Barnes AJ, Locke P, Scudder PR, Dormandy TL, Dormandy JA, Slack J (1977) Is hyperviscosity a treatable component of diabetic microcirculatory disease? Lancet 2:789–791
    • (1977) Lancet , vol.2 , pp. 789-791
    • Barnes, A.J.1    Locke, P.2    Scudder, P.R.3    Dormandy, T.L.4    Dormandy, J.A.5    Slack, J.6
  • 92
    • 67650269861 scopus 로고    scopus 로고
    • Elevated triglycerides correlate with progression of diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD1MXos1Cqu70%3D, PID: 19411614
    • Wiggin TD, Sullivan KA, Pop-Busui R, Amato A, Sima AA, Feldman EL (2009) Elevated triglycerides correlate with progression of diabetic neuropathy. Diabetes 58:1634–1640
    • (2009) Diabetes , vol.58 , pp. 1634-1640
    • Wiggin, T.D.1    Sullivan, K.A.2    Pop-Busui, R.3    Amato, A.4    Sima, A.A.5    Feldman, E.L.6
  • 93
    • 84925884366 scopus 로고    scopus 로고
    • The role of statins in the treatment of type 2 diabetes mellitus: an update
    • Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP (2013) The role of statins in the treatment of type 2 diabetes mellitus: an update. Curr Pharm Des 20:3665–3674
    • (2013) Curr Pharm Des , vol.20 , pp. 3665-3674
    • Katsiki, N.1    Athyros, V.G.2    Karagiannis, A.3    Mikhailidis, D.P.4
  • 94
    • 41149125988 scopus 로고    scopus 로고
    • Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: the Fremantle Diabetes Study
    • COI: 1:CAS:528:DC%2BD1cXjsFGiurs%3D, PID: 18193189
    • Davis TM, Yeap BB, Davis WA, Bruce DG (2008) Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: the Fremantle Diabetes Study. Diabetologia 51:562–566
    • (2008) Diabetologia , vol.51 , pp. 562-566
    • Davis, T.M.1    Yeap, B.B.2    Davis, W.A.3    Bruce, D.G.4
  • 95
    • 84916909531 scopus 로고    scopus 로고
    • Statin use before diabetes diagnosis and risk of microvascular disease: a nationwide nested matched study
    • COI: 1:CAS:528:DC%2BC2MXhtlWitbs%3D, PID: 25217178
    • Nielsen SF, Nordestgaard BG (2014) Statin use before diabetes diagnosis and risk of microvascular disease: a nationwide nested matched study. Lancet Diabetes Endocrinol 2:894–900
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 894-900
    • Nielsen, S.F.1    Nordestgaard, B.G.2
  • 96
    • 21844474541 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD2MXlsF2itLc%3D, PID: 15983249
    • Ii M, Nishimura H, Kusano KF et al (2005) Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy. Circulation 112:93–102
    • (2005) Circulation , vol.112 , pp. 93-102
    • Ii, M.1    Nishimura, H.2    Kusano, K.F.3
  • 97
    • 84880687486 scopus 로고    scopus 로고
    • Medical strategies to reduce amputation in patients with type 2 diabetes
    • COI: 1:STN:280:DC%2BC3svhslynsA%3D%3D, PID: 23445087
    • Malik RA, Tesfaye S, Ziegler D (2013) Medical strategies to reduce amputation in patients with type 2 diabetes. Diabet Med 30:893–900
    • (2013) Diabet Med , vol.30 , pp. 893-900
    • Malik, R.A.1    Tesfaye, S.2    Ziegler, D.3
  • 98
    • 2542462256 scopus 로고    scopus 로고
    • Nicotine induces mononuclear leukocyte adhesion and expression of adhesion molecules, VCAM and ICAM, in endothelial cells in vitro
    • PID: 15354631
    • Albaugh G, Bellavance E, Strande L, Heinburger S, Hewitt CW, Alexander JB (2004) Nicotine induces mononuclear leukocyte adhesion and expression of adhesion molecules, VCAM and ICAM, in endothelial cells in vitro. Ann Vasc Surg 18:302–307
    • (2004) Ann Vasc Surg , vol.18 , pp. 302-307
    • Albaugh, G.1    Bellavance, E.2    Strande, L.3    Heinburger, S.4    Hewitt, C.W.5    Alexander, J.B.6
  • 99
    • 0344110498 scopus 로고    scopus 로고
    • Nicotine induces leukocyte rolling and adhesion in the cerebral microcirculation of the mouse
    • COI: 1:CAS:528:DyaK2sXnsVyhsr8%3D, PID: 9413272
    • Yong T, Zheng MQ, Linthicum DS (1997) Nicotine induces leukocyte rolling and adhesion in the cerebral microcirculation of the mouse. J Neuroimmunol 80:158–164
    • (1997) J Neuroimmunol , vol.80 , pp. 158-164
    • Yong, T.1    Zheng, M.Q.2    Linthicum, D.S.3
  • 100
    • 19944433694 scopus 로고    scopus 로고
    • Vascular risk factors and diabetic neuropathy
    • COI: 1:CAS:528:DC%2BD2MXnvVKntw%3D%3D, PID: 15673800
    • Tesfaye S, Chaturvedi N, Eaton SE et al (2005) Vascular risk factors and diabetic neuropathy. N Engl J Med 352:341–350
    • (2005) N Engl J Med , vol.352 , pp. 341-350
    • Tesfaye, S.1    Chaturvedi, N.2    Eaton, S.E.3
  • 101
    • 0033538267 scopus 로고    scopus 로고
    • Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins
    • COI: 1:CAS:528:DyaK1MXktVejurc%3D, PID: 10367822
    • Nappo F, de Rosa N, Marfella R et al (1999) Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins. JAMA 281:2113–2118
    • (1999) JAMA , vol.281 , pp. 2113-2118
    • Nappo, F.1    de Rosa, N.2    Marfella, R.3
  • 102
    • 0035042343 scopus 로고    scopus 로고
    • Relation between homocysteinaemia and diabetic neuropathy in patients with type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD3MXjslKns7c%3D, PID: 11318838
    • Ambrosch A, Dierkes J, Lobmann R et al (2001) Relation between homocysteinaemia and diabetic neuropathy in patients with type 2 diabetes mellitus. Diabet Med 18:185–192
    • (2001) Diabet Med , vol.18 , pp. 185-192
    • Ambrosch, A.1    Dierkes, J.2    Lobmann, R.3
  • 103
    • 74249095708 scopus 로고    scopus 로고
    • Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy
    • COI: 1:CAS:528:DC%2BC3cXht1Kitbg%3D, PID: 19846797
    • Wile DJ, Toth C (2010) Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy. Diabetes Care 33:156–161
    • (2010) Diabetes Care , vol.33 , pp. 156-161
    • Wile, D.J.1    Toth, C.2
  • 104
    • 84866671750 scopus 로고    scopus 로고
    • Dynamic light scattering optical coherence tomography
    • PID: 23037374
    • Lee J, Wu W, Jiang JY, Zhu B, Boas DA (2012) Dynamic light scattering optical coherence tomography. Opt Express 20:22262–22277
    • (2012) Opt Express , vol.20 , pp. 22262-22277
    • Lee, J.1    Wu, W.2    Jiang, J.Y.3    Zhu, B.4    Boas, D.A.5
  • 105
    • 77956323278 scopus 로고    scopus 로고
    • Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue
    • COI: 1:CAS:528:DC%2BC3cXpvVWgsrg%3D, PID: 20693997
    • Sakadzic S, Roussakis E, Yaseen MA et al (2010) Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods 7:755–759
    • (2010) Nat Methods , vol.7 , pp. 755-759
    • Sakadzic, S.1    Roussakis, E.2    Yaseen, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.