Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 7, 2015, Pages 1638-1650

  Hansen, Mette R ^a   Jakobsen, Tim H ^b   Bang, Claus G ^a   Cohrt, Anders Emil ^a   Hansen, Casper L ^a   Clausen, Janie W ^a   Le Quement, Sebastian T ^a   Tolker Nielsen, Tim ^b   Givskov, Michael ^b,c   Nielsen, Thomas E ^a,c  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

1,2,3 Triazole; Antibiotics; Homoserine lactone; Pseudomonas aeruginosa; Quorum sensing

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; 1,4 TRIAZOLE LACTONE; 1,4 TRIAZOLE LACTONE DERIVATIVE; 1,5 TRIAZOLE LACTONE; 1,5 TRIAZOLE LACTONE DERIVATIVE; BACTERIAL PROTEIN; GREEN FLUORESCENT PROTEIN; N ACYLHOMOSERINE LACTONE; N ACYLHOMOSERINE LACTONE SULFIDE; N ACYLHOMOSERINE LACTONE SULFONAMIDE; N ACYLHOMOSERINE LACTONE SULFONE; N ACYLHOMOSERINE LACTONE SULFOXIDE; PEPTIDO TRIAZOLE N ACYLHOMOSERINE LACTONE DERIVATIVE; PROTEIN LASR; UNCLASSIFIED DRUG; GAMMA BUTYROLACTONE; HOMOSERINE LACTONE; TRIAZOLE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CHEMICAL REACTION KINETICS; CONCENTRATION RESPONSE; NONHUMAN; PHYSICAL PARAMETERS; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ANALOGS AND DERIVATIVES; CHEMISTRY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; HUMAN; PHYSIOLOGY; PROCEDURES;

4-BUTYROLACTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HUMANS; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; TRIAZOLES;

EID: 84925462987     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.01.038     Document Type: Article

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