Solid-phase synthesis of structurally diverse heterocycles by an amide-ketone condensation/N-acyliminium pictet-spengler sequence

Chemistry - A European Journal

Volumn 18, Issue 52, 2012, Pages 16793-16800

  Komnatnyy, Vitaly V ^a   Givskov, Michael ^b,c   Nielsen, Thomas E ^a,c  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

cyclization; heterocycles; solid phase synthesis; tetrahydro carbolines

Indexed keywords

AMIDES; AMINO ACIDS; CONDENSATION; CONDENSATION REACTIONS; KETONES; NUCLEOPHILES; REACTION INTERMEDIATES; SCAFFOLDS; SYNTHESIS (CHEMICAL);

BICYCLIC RING SYSTEM; CARBOLINES; CYCLIZATION REACTIONS; HETEROCYCLES; HETEROCYCLIC COMPOUND; REACTION CONDITIONS; RELEASE MECHANISM; SOLID PHASE SYNTHESIS;

CYCLIZATION;

EID: 84872956964     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201202745     Document Type: Article

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