Vascular biology: Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation

Science Signaling

Volumn 8, Issue 358, 2015, Pages

  Sullivan, Michelle N ^a   Gonzales, Albert L ^b   Pires, Paulo W ^c   Bruhl, Allison ^a   Leo, M Dennis ^d   Li, Wencheng ^a   Oulidi, Agathe ^c   Boop, Frederick A ^d   Feng, Yumei ^a   Jaggar, Jonathan H ^d   Welsh, Donald G ^e   Earley, Scott ^c  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; 4-HYDROXY-2-NONENAL; ALDEHYDE; CALCIUM CHANNEL; CYBB PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRPA1 PROTEIN, HUMAN;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BRAIN ARTERY; CALCIUM SIGNALING; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; KIDNEY CELL; LIPID PEROXIDATION; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE; STIMULATION; VASODILATATION; ANIMAL; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; MEMBRANE POTENTIAL; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ALDEHYDES; ANIMALS; BLOTTING, WESTERN; CALCIUM CHANNELS; CALCIUM SIGNALING; CEREBRAL ARTERIES; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIPID PEROXIDATION; MEMBRANE GLYCOPROTEINS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSIENT RECEPTOR POTENTIAL CHANNELS; VASODILATION;

EID: 84925458230     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005659     Document Type: Article

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