메뉴 건너뛰기




Volumn 20, Issue 3, 2015, Pages 263-269

TERT promoter mutations and TERT MRNa but not FGFR3 mutations are urinary biomarkers in han chinese patients with urothelial bladder cancer

Author keywords

FGFR3; Telomerase; TERT; Urinary markers; Urothelial bladder cancer

Indexed keywords

BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MESSENGER RNA; TELOMERASE REVERSE TRANSCRIPTASE; FGFR3 PROTEIN, HUMAN; TELOMERASE; TERT PROTEIN, HUMAN; TUMOR MARKER;

EID: 84925452904     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2014-0391     Document Type: Article
Times cited : (29)

References (46)
  • 1
    • 84876482422 scopus 로고    scopus 로고
    • Current perspectives in bladder cancer management
    • Griffiths TR. Current perspectives in bladder cancer management. Int J Clin Pract 2013;67: 435–448.
    • (2013) Int J Clin Pract , vol.67 , pp. 435-448
    • Griffiths, T.R.1
  • 2
    • 84858750992 scopus 로고    scopus 로고
    • Regulation of the human catalytic subunit of telomerase (hTERT)
    • Daniel M, Peek GW, Tollefsbol TO. Regulation of the human catalytic subunit of telomerase (hTERT). Gene 2012;498:135–146.
    • (2012) Gene , vol.498 , pp. 135-146
    • Daniel, M.1    Peek, G.W.2    Tollefsbol, T.O.3
  • 3
    • 82755192899 scopus 로고    scopus 로고
    • Role of telomeres and telomerase in cancer
    • Shay JW, Wright WE. Role of telomeres and telomerase in cancer. Semin Cancer Biol 2011;21: 349–353.
    • (2011) Semin Cancer Biol , vol.21 , pp. 349-353
    • Shay, J.W.1    Wright, W.E.2
  • 4
    • 84901987354 scopus 로고    scopus 로고
    • Telomerase as a “stemness” enzyme
    • Kong F, Zheng C, Xu D. Telomerase as a “stemness” enzyme. Sci China Life Sci 2014;57: 564-570.
    • (2014) Sci China Life Sci , vol.57 , pp. 564-570
    • Kong, F.1    Zheng, C.2    Xu, D.3
  • 5
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • Harley CB.Telomerase and cancer therapeutics. Nat Rev Cancer 2008;8:167-179.
    • (2008) Nat Rev Cancer , vol.8 , pp. 167-179
    • Harley, C.B.1
  • 6
    • 0037650159 scopus 로고    scopus 로고
    • Telomerase as tumor marker
    • Hiyama E, Hiyama K. Telomerase as tumor marker. Cancer Lett 2003;194:221-233.
    • (2003) Cancer Lett , vol.194 , pp. 221-233
    • Hiyama, E.1    Hiyama, K.2
  • 7
    • 84906976007 scopus 로고    scopus 로고
    • Advanced pancreatic cancer: Flourishing novel approaches in the era of biological therapy
    • Chiu JW, Wong H, Leung R et al. Advanced pancreatic cancer: Flourishing novel approaches in the era of biological therapy. The Oncologist 2014; 19:937-950.
    • (2014) The Oncologist , vol.19 , pp. 937-950
    • Chiu, J.W.1    Wong, H.2    Leung, R.3
  • 8
    • 84864935205 scopus 로고    scopus 로고
    • Urine telomerase for diagnosis and surveillance of bladder cancer
    • Lamarca A, Barriuso J. Urine telomerase for diagnosis and surveillance of bladder cancer. Adv Urol 2012;693631.
    • (2012) Adv Urol , pp. 693631
    • Lamarca, A.1    Barriuso, J.2
  • 9
    • 27244433839 scopus 로고    scopus 로고
    • Relevance of urine telomerase in the diagnosis of bladder cancer
    • Sanchini MA, Gunelli R, Nanni O. et al. Relevance of urine telomerase in the diagnosis of bladder cancer. JAMA 2005;294:2052-2056.
    • (2005) JAMA , vol.294 , pp. 2052-2056
    • Sanchini, M.A.1    Gunelli, R.2    Nanni, O.3
  • 10
    • 0032746020 scopus 로고    scopus 로고
    • Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer
    • Suzuki T, Suzuki Y, Fujioka T. Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer. J Urol 1999;162: 2217-2220.
    • (1999) J Urol , vol.162 , pp. 2217-2220
    • Suzuki, T.1    Suzuki, Y.2    Fujioka, T.3
  • 11
    • 25444526972 scopus 로고    scopus 로고
    • Quantitative evaluation of telomerase subunits in urine as biomarkers for noninvasive detection of bladder cancer
    • Weikert S, Krause H, Wolff I et al. Quantitative evaluation of telomerase subunits in urine as biomarkers for noninvasive detection of bladder cancer. Int J Cancer 2005;117:274-280.
    • (2005) Int J Cancer , vol.117 , pp. 274-280
    • Weikert, S.1    Krause, H.2    Wolff, I.3
  • 12
    • 0031024372 scopus 로고    scopus 로고
    • Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine
    • Yoshida K, Sugino T, Tahara H et al.Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine. Cancer 1997;79:362-369.
    • (1997) Cancer , vol.79 , pp. 362-369
    • Yoshida, K.1    Sugino, T.2    Tahara, H.3
  • 13
    • 85028141478 scopus 로고    scopus 로고
    • The age-and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
    • Liu T, Wang N, Cao J et al.The age-and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas. Oncogene 2014;33:4978-4984.
    • (2014) Oncogene , vol.33 , pp. 4978-4984
    • Liu, T.1    Wang, N.2    Cao, J.3
  • 14
    • 0030942640 scopus 로고    scopus 로고
    • Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer
    • Kinoshita H, Ogawa O, Kakehi Y et al. Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer. J Natl Cancer Inst 1997;89:724-730.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 724-730
    • Kinoshita, H.1    Ogawa, O.2    Kakehi, Y.3
  • 15
    • 0036165730 scopus 로고    scopus 로고
    • Prospective evaluation of genetic abnormalities and telomerase expression in exfoliated urinary cells for bladder cancer detection
    • Neves M, Ciofu C, Larousserie F et al. Prospective evaluation of genetic abnormalities and telomerase expression in exfoliated urinary cells for bladder cancer detection. J Urol 2002;167: 1276-1281.
    • (2002) J Urol , vol.167 , pp. 1276-1281
    • Neves, M.1    Ciofu, C.2    Larousserie, F.3
  • 16
    • 0031885140 scopus 로고    scopus 로고
    • Nonradioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine
    • Heine B, Hummel M, Müller M et al. Nonradioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine. J Pathol 1998;184:71-76.
    • (1998) J Pathol , vol.184 , pp. 71-76
    • Heine, B.1    Hummel, M.2    Müller, M.3
  • 17
    • 0031747370 scopus 로고    scopus 로고
    • Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer
    • Ito H, Kyo S, Kanaya T et al. Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer. Clin Cancer Res 1998;4:1603-1608.
    • (1998) Clin Cancer Res , vol.4 , pp. 1603-1608
    • Ito, H.1    Kyo, S.2    Kanaya, T.3
  • 18
    • 2642693706 scopus 로고    scopus 로고
    • Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity
    • Kavaler E, Landman J, Chang Y et al. Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity. Cancer 1998;82:708-714.
    • (1998) Cancer , vol.82 , pp. 708-714
    • Kavaler, E.1    Landman, J.2    Chang, Y.3
  • 19
    • 84874191269 scopus 로고    scopus 로고
    • TERTpromoter mutations in familial and sporadic melanoma
    • Horn S, Figl A, Rachakonda PS et al. TERT promoter mutations in familial and sporadic melanoma. Science 2013;339:959-961.
    • (2013) Science , vol.339 , pp. 959-961
    • Horn, S.1    Figl, A.2    Rachakonda, P.S.3
  • 20
    • 84874189784 scopus 로고    scopus 로고
    • Highly recurrent TERT promoter mutations in human melanoma
    • Huang FW, Hodis E, Xu MJ et al. Highly recurrent TERT promoter mutations in human melanoma. Science 2013;339:957-959.
    • (2013) Science , vol.339 , pp. 957-959
    • Huang, F.W.1    Hodis, E.2    Xu, M.J.3
  • 21
    • 84891828969 scopus 로고    scopus 로고
    • Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine
    • Hurst CD, Platt FM, Knowles MA. Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine. Eur Urol 2014;65:367-369.
    • (2014) Eur Urol , vol.65 , pp. 367-369
    • Hurst, C.D.1    Platt, F.M.2    Knowles, M.A.3
  • 22
    • 84876067164 scopus 로고    scopus 로고
    • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
    • Killela PJ, Reitman ZJ, Jiao Y et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci USA 2013; 110:6021-6026.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 6021-6026
    • Killela, P.J.1    Reitman, Z.J.2    Jiao, Y.3
  • 23
    • 84891833965 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: A genomic and molecular study
    • Wu S, Huang P, Li C et al. Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: A genomic and molecular study. Eur Urol 2014;65:274-277.
    • (2014) Eur Urol , vol.65 , pp. 274-277
    • Wu, S.1    Huang, P.2    Li, C.3
  • 24
    • 84886390673 scopus 로고    scopus 로고
    • TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification byacommon polymorphism
    • Rachakonda PS, Hosen I, de Verdier PJ et al. TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification byacommon polymorphism. ProcNatl Acad Sci USA 2013;110:17426-17431.
    • (2013) Procnatl Acad Sci USA , vol.110 , pp. 17426-17431
    • Rachakonda, P.S.1    Hosen, I.2    De Verdier, P.J.3
  • 25
    • 84899004976 scopus 로고    scopus 로고
    • TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomas
    • Wang K, Liu T, Liu L et al. TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomas. Oncotarget 2014;5: 1829-1836.
    • (2014) Oncotarget , vol.5 , pp. 1829-1836
    • Wang, K.1    Liu, T.2    Liu, L.3
  • 26
    • 84908556575 scopus 로고    scopus 로고
    • TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA
    • Wang N, Liu T, Sofiadis A et al. TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA. Cancer 2014;120:2965-2979.
    • (2014) Cancer , vol.120 , pp. 2965-2979
    • Wang, N.1    Liu, T.2    Sofiadis, A.3
  • 27
    • 84877967061 scopus 로고    scopus 로고
    • Highly prevalent TERT
    • Liu X, Wu G, Shan Y et al. Highly prevalent TERT promoter mutations in bladder cancer and glioblastoma. Cell Cycle 2013;12:1637-1638.
    • (2013) Cell Cycle , vol.12 , pp. 1637-1638
    • Liu, X.1    Wu, G.2    Shan, Y.3
  • 28
    • 84891835829 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase promoter mutations in bladder cancer: High frequency across stages, detection in urine, and lack of association with outcome
    • Allory Y, Beukers W, Sagrera A et al.Telomerase reverse transcriptase promoter mutations in bladder cancer: High frequency across stages, detection in urine, and lack of association with outcome. Eur Urol 2014;65:360-366.
    • (2014) Eur Urol , vol.65 , pp. 360-366
    • Allory, Y.1    Beukers, W.2    Sagrera, A.3
  • 29
    • 84903607788 scopus 로고    scopus 로고
    • The activating
    • Liu T, Brown TC, Juhlin CC et al.The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors. Endocr Relat Cancer 2014;21:427-434.
    • (2014) Endocr Relat Cancer , vol.21 , pp. 427-434
    • Liu, T.1    Brown, T.C.2    Juhlin, C.C.3
  • 30
    • 84919954084 scopus 로고    scopus 로고
    • TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
    • Xie H, Liu T, Wang N et al. TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma. Oncotarget 2014;5:10048-10057.
    • (2014) Oncotarget , vol.5 , pp. 10048-10057
    • Xie, H.1    Liu, T.2    Wang, N.3
  • 31
    • 36248943079 scopus 로고    scopus 로고
    • Role of FGFR3 in urothelial cell carcinoma: Biomarker and potential therapeutic target
    • Knowles MA. Role of FGFR3 in urothelial cell carcinoma: Biomarker and potential therapeutic target. World J Urol 2007;25:581-593.
    • (2007) World J Urol , vol.25 , pp. 581-593
    • Knowles, M.A.1
  • 32
    • 66749102156 scopus 로고    scopus 로고
    • Lurkin I et al.The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour
    • Kompier LC, van der Aa MN, Lurkin I et al.The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour. J Pathol 2009;218:104-112.
    • (2009) J Pathol , vol.218 , pp. 104-112
    • Kompier, L.C.1    Van Der Aa, M.N.2
  • 33
    • 33751024894 scopus 로고    scopus 로고
    • Molecular profiling of bladder tumors based on the detection of FGFR3 and TP53 mutations
    • Lamy A, Gobet F, Laurent M et al. Molecular profiling of bladder tumors based on the detection of FGFR3 and TP53 mutations. J Urol 2006;176: 2686-2689.
    • (2006) J Urol , vol.176 , pp. 2686-2689
    • Lamy, A.1    Gobet, F.2    Laurent, M.3
  • 34
    • 48549105755 scopus 로고    scopus 로고
    • Recurrent and multiple bladder tumors show conserved expression profiles
    • Lindgren D, Gudjonsson S, Jee KJ et al. Recurrent and multiple bladder tumors show conserved expression profiles. BMC Cancer 2008;8:183.
    • (2008) BMC Cancer , vol.8 , pp. 183
    • Lindgren, D.1    Gudjonsson, S.2    Jee, K.J.3
  • 35
    • 13444279152 scopus 로고    scopus 로고
    • Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: Contribution of exogenous versus endogenous carcinogens
    • Wallerand H, Bakkar AA, de Medina SG et al. Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: Contribution of exogenous versus endogenous carcinogens. Carcinogenesis 2005;26:177-184.
    • (2005) Carcinogenesis , vol.26 , pp. 177-184
    • Wallerand, H.1    Bakkar, A.A.2    De Medina, S.G.3
  • 36
    • 84876286597 scopus 로고    scopus 로고
    • FGFR3 mutation analysis in voided urine samples to decrease cystoscopies and cost in nonmuscle invasive bladder cancer surveillance: A comparison of 3 strategies
    • van Kessel KE, Kompier LC, de Bekker-Grob EW et al. FGFR3 mutation analysis in voided urine samples to decrease cystoscopies and cost in nonmuscle invasive bladder cancer surveillance: A comparison of 3 strategies. J Urol 2013;189:1676-1681.
    • (2013) J Urol , vol.189 , pp. 1676-1681
    • Van Kessel, K.E.1    Kompier, L.C.2    De Bekker-Grob, E.W.3
  • 37
    • 58849152774 scopus 로고    scopus 로고
    • FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours
    • van Oers JM, Zwarthoff EC, Rehman I et al. FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours. Eur Urol 2009;55:650-657.
    • (2009) Eur Urol , vol.55 , pp. 650-657
    • Van Oers, J.M.1    Zwarthoff, E.C.2    Rehman, I.3
  • 38
    • 0035866380 scopus 로고    scopus 로고
    • Thefibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • van Rhijn BW, Lurkin I, Radvanyi F et al. The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate. Cancer Res 2001; 61:1265-1268.
    • (2001) Cancer Res , vol.61 , pp. 1265-1268
    • Van Rhijn, B.W.1    Lurkin, I.2    Radvanyi, F.3
  • 39
    • 23444440484 scopus 로고    scopus 로고
    • FGFR3and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma
    • Jebar AH, Hurst CD, Tomlinson DC et al. FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 2005;24:5218-5225.
    • (2005) Oncogene , vol.24 , pp. 5218-5225
    • Jebar, A.H.1    Hurst, C.D.2    Tomlinson, D.C.3
  • 40
    • 79251526177 scopus 로고    scopus 로고
    • Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer
    • Dodurga Y, Tataroglu C, Kesen Z et al. Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer. Genet Mol Res 2011;10:86-95.
    • (2011) Genet Mol Res , vol.10 , pp. 86-95
    • Dodurga, Y.1    Tataroglu, C.2    Kesen, Z.3
  • 41
    • 71849086230 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non-muscle invasive bladder cancer
    • Miyake M, Sugano K, Sugino H et al. Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non-muscle invasive bladder cancer. Cancer Sci 2010;101:250-258.
    • (2010) Cancer Sci , vol.101 , pp. 250-258
    • Miyake, M.1    Sugano, K.2    Sugino, H.3
  • 42
    • 0042572486 scopus 로고    scopus 로고
    • Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection
    • Rieger-Christ KM, Mourtzinos A, Lee PJ et al. Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection. Cancer 2003;98:737-744.
    • (2003) Cancer , vol.98 , pp. 737-744
    • Rieger-Christ, K.M.1    Mourtzinos, A.2    Lee, P.J.3
  • 43
    • 33747079040 scopus 로고    scopus 로고
    • Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas
    • Hernandez S, Lopez-Knowles E, Lloreta J et al. Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas. J Clin Oncol 2006;24:3664-3671.
    • (2006) J Clin Oncol , vol.24 , pp. 3664-3671
    • Hernandez, S.1    Lopez-Knowles, E.2    Lloreta, J.3
  • 44
    • 84864837388 scopus 로고    scopus 로고
    • Biomarkers for bladder cancer aggressiveness
    • Frantzi M, Makridakis M, Vlahou A. Biomarkers for bladder cancer aggressiveness. Curr Opin Urol 2012;22:390-396.
    • (2012) Curr Opin Urol , vol.22 , pp. 390-396
    • Frantzi, M.1    Makridakis, M.2    Vlahou, A.3
  • 45
    • 34250305542 scopus 로고    scopus 로고
    • Urine telomerase activity for the detection of bladder cancer in females
    • Bravaccini S, Sanchini MA, Granato AM et al. Urine telomerase activity for the detection of bladder cancer in females. J Urol 2007;178:57-61.
    • (2007) J Urol , vol.178 , pp. 57-61
    • Bravaccini, S.1    Sanchini, M.A.2    Granato, A.M.3
  • 46
    • 78650169276 scopus 로고    scopus 로고
    • FGFR3mutational status and protein expression in patients with bladder cancer in a Jordanian population
    • Bodoor K, Ghabkari A, Jaradat Z et al. FGFR3 mutational status and protein expression in patients with bladder cancer in a Jordanian population. Cancer Epidemiol 2010;34:724-732.
    • (2010) Cancer Epidemiol , vol.34 , pp. 724-732
    • Bodoor, K.1    Ghabkari, A.2    Jaradat, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.