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Volumn 35, Issue 3, 2015, Pages 251-259

Transition from dexmedetomidine to enteral clonidine for ICU sedation: An observational pilot study

Author keywords

adverse effects; alpha 2 agonist; analgesia; clonidine; critical care; dexmedetomidine; intensive care; pharmacoeconomics; sedation

Indexed keywords

CLONIDINE; DEXMEDETOMIDINE; FENTANYL; LORAZEPAM; NEUROLEPTIC AGENT; OPIATE; PHENOBARBITAL; PROPOFOL; PSYCHOTROPIC AGENT; VALPROIC ACID; HYPNOTIC SEDATIVE AGENT;

EID: 84925448888     PISSN: 02770008     EISSN: 18759114     Source Type: Journal    
DOI: 10.1002/phar.1559     Document Type: Article
Times cited : (55)

References (45)
  • 1
    • 84903840423 scopus 로고    scopus 로고
    • Agitation onset, frequency, and associated temporal factors in critically ill adults
    • Burk RS, Grap M, Munro CL, Schubert CM, Sessler CN,. Agitation onset, frequency, and associated temporal factors in critically ill adults. Am J Crit Care 2014; 23: 296-304.
    • (2014) Am J Crit Care , vol.23 , pp. 296-304
    • Burk, R.S.1    Grap, M.2    Munro, C.L.3    Schubert, C.M.4    Sessler, C.N.5
  • 2
    • 27144482368 scopus 로고    scopus 로고
    • A prospective study of agitation in a medical-surgical ICU: Incidence, risk factors, and outcomes
    • Jaber S, Chanques G, Altairac C, et al. A prospective study of agitation in a medical-surgical ICU: incidence, risk factors, and outcomes. Chest 2005; 128: 2749-57.
    • (2005) Chest , vol.128 , pp. 2749-2757
    • Jaber, S.1    Chanques, G.2    Altairac, C.3
  • 3
    • 3042693285 scopus 로고    scopus 로고
    • Severe agitation among ventilated medical intensive care unit patients: Frequency, characteristics and outcomes
    • Woods JC, Mion LC, Connor JT, et al. Severe agitation among ventilated medical intensive care unit patients: frequency, characteristics and outcomes. Intensive Care Med 2004; 30: 1066-72.
    • (2004) Intensive Care Med , vol.30 , pp. 1066-1072
    • Woods, J.C.1    Mion, L.C.2    Connor, J.T.3
  • 4
    • 0030669911 scopus 로고    scopus 로고
    • Characteristics and outcomes of patients who self-extubate from ventilatory support: A case-control study
    • Atkins PM, Mion LC, Mendelson W, Palmer RM, Slomka J, Franko T,. Characteristics and outcomes of patients who self-extubate from ventilatory support: a case-control study. Chest 1997; 112: 1317-23.
    • (1997) Chest , vol.112 , pp. 1317-1323
    • Atkins, P.M.1    Mion, L.C.2    Mendelson, W.3    Palmer, R.M.4    Slomka, J.5    Franko, T.6
  • 5
    • 84872087535 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit
    • Barr J, Fraser GL, Puntillo K, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41: 263-306.
    • (2013) Crit Care Med , vol.41 , pp. 263-306
    • Barr, J.1    Fraser, G.L.2    Puntillo, K.3
  • 6
    • 59649127447 scopus 로고    scopus 로고
    • Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial
    • Riker RR, Shehabi Y, Bokesch PM, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009; 301: 489-99.
    • (2009) JAMA , vol.301 , pp. 489-499
    • Riker, R.R.1    Shehabi, Y.2    Bokesch, P.M.3
  • 7
    • 84858657050 scopus 로고    scopus 로고
    • Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: Two randomized controlled trials
    • Jakob SM, Ruokonen E, Grounds RM, et al. Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA 2012; 307: 1151-60.
    • (2012) JAMA , vol.307 , pp. 1151-1160
    • Jakob, S.M.1    Ruokonen, E.2    Grounds, R.M.3
  • 8
    • 84883590421 scopus 로고    scopus 로고
    • Benzodiazepine versus nonbenzodiazepine-based sedation for mechanically ventilated, critically ill adults: A systematic review and meta-analysis of randomized trials
    • Fraser GL, Devlin JW, Worby CP, et al. Benzodiazepine versus nonbenzodiazepine-based sedation for mechanically ventilated, critically ill adults: a systematic review and meta-analysis of randomized trials. Crit Care Med 2013; 41 (9 Suppl 1): S30-8.
    • (2013) Crit Care Med , vol.41 , Issue.9 , pp. S30-S38
    • Fraser, G.L.1    Devlin, J.W.2    Worby, C.P.3
  • 9
    • 37149040245 scopus 로고    scopus 로고
    • Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial
    • Pandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007; 298: 2644-53.
    • (2007) JAMA , vol.298 , pp. 2644-2653
    • Pandharipande, P.P.1    Pun, B.T.2    Herr, D.L.3
  • 10
    • 77955173168 scopus 로고    scopus 로고
    • Dexmedetomidine in the care of critically ill patients from 2001 to 2007: An observational cohort study
    • Wunsch H, Kahn JM, Kramer AA, et al. Dexmedetomidine in the care of critically ill patients from 2001 to 2007: an observational cohort study. Anesthesiology 2010; 113: 386-94.
    • (2010) Anesthesiology , vol.113 , pp. 386-394
    • Wunsch, H.1    Kahn, J.M.2    Kramer, A.A.3
  • 11
    • 72249085956 scopus 로고    scopus 로고
    • An updated focused review of dexmedetomidine in adults
    • Gerlach AT, Murphy CV, Dasta JF,. An updated focused review of dexmedetomidine in adults. Ann Pharmacother 2009; 43: 2064-74.
    • (2009) Ann Pharmacother , vol.43 , pp. 2064-2074
    • Gerlach, A.T.1    Murphy, C.V.2    Dasta, J.F.3
  • 12
    • 67649354229 scopus 로고    scopus 로고
    • Pharmacology of sedative-analgesic agents: Dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists
    • vii
    • Panzer O, Moitra V, Sladen RN,. Pharmacology of sedative-analgesic agents: dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists. Crit Care Clin 2009; 25: 451-69, vii.
    • (2009) Crit Care Clin , vol.25 , pp. 451-469
    • Panzer, O.1    Moitra, V.2    Sladen, R.N.3
  • 13
    • 74949137504 scopus 로고    scopus 로고
    • A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit
    • Dasta JF, Kane-Gill SL, Pencina M, et al. A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit. Crit Care Med 2010; 38: 497-503.
    • (2010) Crit Care Med , vol.38 , pp. 497-503
    • Dasta, J.F.1    Kane-Gill, S.L.2    Pencina, M.3
  • 14
    • 33744463650 scopus 로고    scopus 로고
    • Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: An outcomes analysis
    • Dasta JF, Jacobi J, Sesti AM, McLaughlin TP,. Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis. Pharmacotherapy 2006; 26: 798-805.
    • (2006) Pharmacotherapy , vol.26 , pp. 798-805
    • Dasta, J.F.1    Jacobi, J.2    Sesti, A.M.3    McLaughlin, T.P.4
  • 15
    • 84906069865 scopus 로고    scopus 로고
    • Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults
    • Bioc JJ, Magee C, Cucchi J, et al. Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults. J Crit Care 2014; 29 (5): 753-757.
    • (2014) J Crit Care , vol.29 , Issue.5 , pp. 753-757
    • Bioc, J.J.1    Magee, C.2    Cucchi, J.3
  • 16
    • 84863585302 scopus 로고    scopus 로고
    • Dexmedetomidine and clonidine: From second- to first-line sedative agents in the critical care setting?
    • Pichot C, Ghignone M, Quintin L,. Dexmedetomidine and clonidine: from second- to first-line sedative agents in the critical care setting? J Intensive Care Med 2012; 27: 219-37.
    • (2012) J Intensive Care Med , vol.27 , pp. 219-237
    • Pichot, C.1    Ghignone, M.2    Quintin, L.3
  • 17
    • 84925393531 scopus 로고    scopus 로고
    • Off-label use of clonidine for sedation in Dutch ICUs
    • Van der Valk J, Zeeman M, Arbouw M, Van den Oever H,. Off-label use of clonidine for sedation in Dutch ICUs. Crit Care 2014; 18 (Suppl 1): P415.
    • (2014) Crit Care , vol.18 , Issue.1 , pp. P415
    • Van Der Valk, J.1    Zeeman, M.2    Arbouw, M.3    Van Den Oever, H.4
  • 18
    • 84858957395 scopus 로고    scopus 로고
    • Clonidine in adults as a sedative agent in the intensive care unit
    • Jamadarkhana S, Gopal S,. Clonidine in adults as a sedative agent in the intensive care unit. J Anaesthesiol Clin Pharmacol 2010; 26: 439-45.
    • (2010) J Anaesthesiol Clin Pharmacol , vol.26 , pp. 439-445
    • Jamadarkhana, S.1    Gopal, S.2
  • 19
    • 84904193432 scopus 로고    scopus 로고
    • Continuous infusion of clonidine in ventilated newborns and infants: A randomized controlled trial
    • Hünseler C, Balling G, Röhlig C, et al. Continuous infusion of clonidine in ventilated newborns and infants: a randomized controlled trial. Pediatr Crit Care Med 2014; 15: 511-22.
    • (2014) Pediatr Crit Care Med , vol.15 , pp. 511-522
    • Hünseler, C.1    Balling, G.2    Röhlig, C.3
  • 22
    • 4143075732 scopus 로고    scopus 로고
    • Use of oral clonidine for sedation in ventilated paediatric intensive care patients
    • Arenas-Lõpez S, Riphagen S, Tibby SM, et al. Use of oral clonidine for sedation in ventilated paediatric intensive care patients. Intensive Care Med 2004; 30: 1625-9.
    • (2004) Intensive Care Med , vol.30 , pp. 1625-1629
    • Arenas-Lõpez, S.1    Riphagen, S.2    Tibby, S.M.3
  • 23
    • 84906056627 scopus 로고    scopus 로고
    • Clonidine in the sedation of mechanically ventilated children: A pilot randomized trial
    • Duffett M, Choong K, Foster J, et al. Clonidine in the sedation of mechanically ventilated children: a pilot randomized trial. J Crit Care 2014; 29 (5): 758-763.
    • (2014) J Crit Care , vol.29 , Issue.5 , pp. 758-763
    • Duffett, M.1    Choong, K.2    Foster, J.3
  • 24
    • 84925440848 scopus 로고    scopus 로고
    • Transitioning patients treated with dexmedetomidine to enteral clonidine: A retrospective study [abstract]
    • Glisic E, Riker R, Kelner A, Perrey H, Fraser G,. Transitioning patients treated with dexmedetomidine to enteral clonidine: a retrospective study [abstract]. Crit Care Med 2012; 40 (Suppl 12): A1110.
    • (2012) Crit Care Med , vol.40 , Issue.12 , pp. A1110
    • Glisic, E.1    Riker, R.2    Kelner, A.3    Perrey, H.4    Fraser, G.5
  • 25
    • 0018104828 scopus 로고
    • Abrupt cessation of clonidine administration: A prospective study
    • Whitsett TL, Chrysant SG, Dillard BL, Anton AH,. Abrupt cessation of clonidine administration: a prospective study. Am J Cardiol 1978; 41: 1285-90.
    • (1978) Am J Cardiol , vol.41 , pp. 1285-1290
    • Whitsett, T.L.1    Chrysant, S.G.2    Dillard, B.L.3    Anton, A.H.4
  • 26
    • 0019206541 scopus 로고
    • Discontinuation syndrome following cessation of treatment with clonidine and other antihypertensive agents
    • Weber MA,. Discontinuation syndrome following cessation of treatment with clonidine and other antihypertensive agents. J Cardiovasc Pharmacol 1980; 2 (Suppl 1): S73-89.
    • (1980) J Cardiovasc Pharmacol , vol.2 , Issue.1 , pp. S73-S89
    • Weber, M.A.1
  • 27
    • 0015619680 scopus 로고
    • Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management
    • Hansson L, Hunyor SN, Julius S, Hoobler SW,. Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management. Am Heart J 1973; 85: 605-10.
    • (1973) Am Heart J , vol.85 , pp. 605-610
    • Hansson, L.1    Hunyor, S.N.2    Julius, S.3    Hoobler, S.W.4
  • 28
    • 3843122315 scopus 로고    scopus 로고
    • Issues in the clinical use of benzodiazepines: Potency, withdrawal, and rebound
    • Chouinard G,. Issues in the clinical use of benzodiazepines: potency, withdrawal, and rebound. J Clin Psychiatry 2004; 65 (Suppl 5): 7-12.
    • (2004) J Clin Psychiatry , vol.65 , Issue.5 , pp. 7-12
    • Chouinard, G.1
  • 31
    • 84876204648 scopus 로고    scopus 로고
    • RED BOOK Online
    • Greenwood Village, CO: Truven Health Analytics;. Accessed June 4
    • Micromedex Healthcare Series. RED BOOK Online. Greenwood Village, CO: Truven Health Analytics; 2013. Accessed June 4, 2014.
    • (2013) Micromedex Healthcare Series
  • 33
    • 58049211820 scopus 로고    scopus 로고
    • Preoperative anxiolytic effect of melatonin and clonidine on postoperative pain and morphine consumption in patients undergoing abdominal hysterectomy: A double-blind, randomized, placebo-controlled study
    • Caumo W, Levandovski R, Hidalgo MP,. Preoperative anxiolytic effect of melatonin and clonidine on postoperative pain and morphine consumption in patients undergoing abdominal hysterectomy: a double-blind, randomized, placebo-controlled study. J Pain 2009; 10: 100-8.
    • (2009) J Pain , vol.10 , pp. 100-108
    • Caumo, W.1    Levandovski, R.2    Hidalgo, M.P.3
  • 34
    • 84861645082 scopus 로고    scopus 로고
    • Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: Systematic review and meta-analysis of randomized controlled trials
    • Blaudszun G, Lysakowski C, Elia N, Tramèr MR,. Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. Anesthesiology 2012; 116: 1312-22.
    • (2012) Anesthesiology , vol.116 , pp. 1312-1322
    • Blaudszun, G.1    Lysakowski, C.2    Elia, N.3    Tramèr, M.R.4
  • 35
    • 84877094687 scopus 로고    scopus 로고
    • Antihyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia
    • Lee C, Kim YD, Kim JN,. Antihyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia. Korean J Anesthesiol 2013; 64: 301-7.
    • (2013) Korean J Anesthesiol , vol.64 , pp. 301-307
    • Lee, C.1    Kim, Y.D.2    Kim, J.N.3
  • 36
    • 0029780058 scopus 로고    scopus 로고
    • Alpha(2)-adrenergic agonists for regional anesthesia. A clinical review of clonidine (1984-1995)
    • Eisenach JC, De Kock M, Klimscha W,. alpha(2)-adrenergic agonists for regional anesthesia. A clinical review of clonidine (1984-1995). Anesthesiology 1996; 85: 655-74.
    • (1996) Anesthesiology , vol.85 , pp. 655-674
    • Eisenach, J.C.1    De Kock, M.2    Klimscha, W.3
  • 37
  • 39
    • 84898670781 scopus 로고    scopus 로고
    • Clonidine in patients undergoing noncardiac surgery
    • Devereaux PJ, Sessler DI, Leslie K, et al. Clonidine in patients undergoing noncardiac surgery. N Engl J Med 2014; 370: 1504-13.
    • (2014) N Engl J Med , vol.370 , pp. 1504-1513
    • Devereaux, P.J.1    Sessler, D.I.2    Leslie, K.3
  • 40
    • 84889063546 scopus 로고    scopus 로고
    • Implementation of a dexmedetomidine stewardship program at a tertiary academic medical center
    • Blum RM, Stevens CA, Carter DM, et al. Implementation of a dexmedetomidine stewardship program at a tertiary academic medical center. Ann Pharmacother 2013; 47: 1400-5.
    • (2013) Ann Pharmacother , vol.47 , pp. 1400-1405
    • Blum, R.M.1    Stevens, C.A.2    Carter, D.M.3
  • 41
    • 38549116067 scopus 로고    scopus 로고
    • Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay
    • Marshall J, Finn CA, Theodore AC,. Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay. Crit Care Med 2008; 36: 427-33.
    • (2008) Crit Care Med , vol.36 , pp. 427-433
    • Marshall, J.1    Finn, C.A.2    Theodore, A.C.3
  • 42
    • 67649361526 scopus 로고    scopus 로고
    • Current sedation practices: Lessons learned from international surveys
    • vii-viii
    • Mehta S, McCullagh I, Burry L,. Current sedation practices: lessons learned from international surveys. Crit Care Clin 2009; 25: 471-88, vii-viii.
    • (2009) Crit Care Clin , vol.25 , pp. 471-488
    • Mehta, S.1    McCullagh, I.2    Burry, L.3
  • 43
    • 84856961636 scopus 로고    scopus 로고
    • Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care-short version
    • Martin J, Heymann A, Bäsell K, et al. Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care-short version. Ger Med Sci 2010; 8: Doc02.
    • (2010) Ger Med Sci , vol.8 , pp. Doc02
    • Martin, J.1    Heymann, A.2    Bäsell, K.3
  • 44
    • 85020029550 scopus 로고    scopus 로고
    • Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients (protocol)
    • Chen K, Lu Z, Xin YC, Cai Y, Chen Y, Pan SM,. Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients (protocol). Cochrane Database Syst Rev 2012; 12: CD010269. doi: 10.1002/14651858.
    • (2012) Cochrane Database Syst Rev , vol.12 , pp. CD010269
    • Chen, K.1    Lu, Z.2    Xin, Y.C.3    Cai, Y.4    Chen, Y.5    Pan, S.M.6
  • 45
    • 33747152472 scopus 로고    scopus 로고
    • Consensus guidelines on sedation and analgesia in critically ill children
    • Playfor S, Jenkins I, Boyles C, et al. Consensus guidelines on sedation and analgesia in critically ill children. Intensive Care Med 2006; 32: 1125-36.
    • (2006) Intensive Care Med , vol.32 , pp. 1125-1136
    • Playfor, S.1    Jenkins, I.2    Boyles, C.3


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