Aspirin and Nonsteroidal Anti-Inflammatory Drugs Can Prevent Cutaneous Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

Journal of Investigative Dermatology

Volumn 135, Issue 4, 2015, Pages 975-983

  Muranushi, Chiho ^a   Olsen, Catherine M ^b   Pandeya, Nirmala ^a,b   Green, Adèle C ^b,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT;

CANCER PREVENTION; CANCER RISK; CASE CONTROL STUDY; DOSE RESPONSE; DRUG USE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SKIN CARCINOMA; SYSTEMATIC REVIEW; CARCINOMA, SQUAMOUS CELL; SKIN NEOPLASMS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICARCINOGENIC AGENTS; ASPIRIN; CARCINOMA, SQUAMOUS CELL; HUMANS; SKIN NEOPLASMS;

EID: 84925444240     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.531     Document Type: Article

References (42)

1. Aggarwal BB, Vijayalekshmi RV, Sung B (2009) Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe. Clin Cancer Res 15:425-30
2. Amari W, Zeringue AL, McDonald JR et al. (2011) Risk of non-melanoma skin cancer in a national cohort of veterans with rheumatoid arthritis. Rheumatology (Oxford) 50:1431-9
3. Armstrong BK, Kricker A (2001) The epidemiology of UV induced skin cancer. J Photochem Photobiol B 63:8-18
4. Asgari MM, Chren MM, Warton EM et al. (2010) Association between nonsteroidal anti-inflammatory drug use and cutaneous squamous cell carcinoma. Arch Dermatol 146:388-95
5. Athar M, An KP, Morel KD et al. (2001) Ultraviolet B(UVB)-induced cox-2 expression in murine skin: an immunohistochemical study. Biochem Biophys Res Commun 280:1042-7
6. Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:088-1101
7. Buckman SY, Gresham A, Hale P et al. (1998) COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer. Carcinogenesis 19:723-9
8. Butler GJ, Neale R, Green AC et al. (2005) Nonsteroidal anti-inflammatory drugs and the risk of actinic keratoses and squamous cell cancers of the skin. J Am Acad Dermatol 53:966-72
9. Clouser MC, Roe DJ, Foote JA et al. (2009) Effect of non-steroidal anti-inflammatory drugs on non-melanoma skin cancer incidence in the SKICAP-AK trial. Pharmacoepidemiol Drug Saf 18:276-83
10. Cochran WG (1954) The combination of estimates from different experiments. Biometrics 10:101-29
11. Cook NR, Lee IM, Gaziano JM et al. (2005) Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA 294:47-55
12. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177-88
13. Egger M, Davey Smith G, Schneider M et al. (1997) Bias in meta-analysis detected by a simple, graphical test. Br Med J 315:629-34
14. Elmets CA, Viner JL, Pentland AP et al. (2010) Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial. J Natl Cancer Inst 102:1835-44
15. Fecker LF, Stockfleth E, Nindl I et al. (2007) The role of apoptosis in therapy and prophylaxis of epithelial tumours by nonsteroidal anti-inflammatory drugs (NSAIDs). Br J Dermatol 156:25-33
16. Grau MV, Baron JA, Langholz B et al. (2006) Effect of NSAIDs on the recurrence of nonmelanoma skin cancer. Int J Cancer 119:682-
17. Guadagni F, Ferroni P, Palmirotta R et al. (2007) Non-steroidal anti-inflammatory drugs in cancer prevention and therapy. Anticancer Res 27:3147-62
18. Hamling J, Lee P, Weitkunat R et al. (2008) Facilitating meta-analyses by deriving relative effect and precision estimates for alternative comparisons from a set of estimates presented by exposure level or disease category. Statistics in medicine 27:954-70
19. Harris RE, Beebe-Donk J, Doss H et al. (2005) Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: a critical review of non-selective COX-2 blockade (review). Oncol Rep 13:559-83
20. Higgins JP, Thompson SG, Deeks JJ et al. (2003) Measuring inconsistency in meta-analyses. Br Med J 327:557-60
21. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2012) A Review of Human Carcinogens. Part D: Radiation Lyon
22. Jeter JM, Han J, Martinez ME et al. (2012) Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses' Health Study. Cancer Causes Control 23:1451-61
23. Johannesdottir SA, Chang ET, Mehnert F et al. (2012) Nonsteroidal anti-inflammatory drugs and the risk of skin cancer: a population-based case-control study. Cancer 118:4768-76
24. Kuzbicki L, Lange D, Stanek-Widera A et al. (2011) Different expression of cyclooxygenase-2 (COX-2) in selected nonmelanocytic human cutaneous lesions. Folia Histochem Cytobiol 49:381-8
25. Lucas RM, McMichael AJ, Armstrong BK et al. (2008) Estimating the global disease burden due to ultraviolet radiation exposure. Int J Epidemiol 37:654-7
26. Martin GM, Stockfleth E (2012) Diclofenac sodium 3% gel for the management of actinic keratosis: 10+ years of cumulative evidence of efficacy and safety. J Drugs Dermatol 11:600-8
27. Maverakis E, Miyamura Y, Bowen MP et al. (2010) Light, including ultraviolet. J Autoimmun 34:J247-57
28. McGillis ST, Fein H (2004) Topical treatment strategies for non-melanoma skin cancer and precursor lesions. Semin Cutan Med Surg 23:174-83
29. Moore DE (2002) Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management. Drug Saf 25:345-72
30. Muller-Decker K, Reinerth G, Krieg P et al. (1999) Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin. Int J Cancer 82:648-56
31. Nunes AP, Lapane KL, Weinstock MA (2011) Association between nonsteroidal anti-inflammatory drugs and keratinocyte carcinomas of the skin among participants in the Veterans Affairs Topical Tretinoin Chemoprevention Trial. Pharmacoepidemiol Drug Saf 20:922-9
32. Rivers JK, McLean DI (1997) An open study to assess the efficacy and safety of topical 3% diclofenac in a 2.5% hyaluronic acid gel for the treatment of actinic keratoses. Arch Dermatol 133:1239-42
33. Rundhaug JE, Simper MS, Surh I et al. (2011) The role of the EP receptors for prostaglandin E2 in skin and skin cancer. Cancer Metastasis Rev 30:465-80
34. Sørensen HT, Johnsen SP, Nørgård B (2001) Methodological issues in using prescription and other databases in pharmacoepidemiology. Norsk Epidemiol 11:13-8
35. Stroup DF, Berlin JA, Morton SC et al. (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283:2008-12
36. Subongkot S, Frame D, Leslie W et al. (2003) Selective cyclooxygenase-2 inhibition: a target in cancer prevention and treatment. Pharmacotherapy 23:9-28
37. Torti DC, Christensen BC, Storm CA et al. (2011) Analgesic and nonsteroidal anti-inflammatory use in relation to nonmelanoma skin cancer: a population-based case-control study. J Am Acad Dermatol 65:304-12
38. Vane JR, Bakhle YS, Botting RM (1998) Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 38:97-120
39. von Elm E, Altman DG, Egger M et al. (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370:1453-7
40. West SL, Savitz DA, Koch G et al. (1995) Recall accuracy for prescription medications: self-report compared with database information. Am J Epidemiol 142:1103-2
41. Wong WC, Cheung CS, Hart GJ (2008) Development of a quality assessment tool for systematic reviews of observational studies (QATSO) of HIV prevalence in men having sex with men and associated risk behaviours. Emerging Themes Epidemiol 5:23
42. Zhang B, Liang X, Ye L et al. (2014) No chemopreventive effect of nonsteroidal anti-inflammatory drugs on nonmelanoma skin cancer: evidence from meta-analysis. PLoS ONE 9:e96887