IL-4Rα-dependent alternative activation of macrophages is not decisive for Mycobacterium tuberculosis pathology and bacterial burden in mice

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Guler, Reto ^a   Parihar, Suraj P ^a   Savvi, Suzana ^a   Logan, Erin ^a   Schwegmann, Anita ^a   Roy, Sugata ^c   Nieuwenhuizen, Natalie E ^a,d   Ozturk, Mumin ^a   Schmeier, Sebastian ^b   Suzuki, Harukazu ^c   Brombacher, Frank ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b MASSEY UNIVERSITY   (New Zealand)

^c RIKEN   (Japan)

^d MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; GRANULOCYTE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; ARG1 PROTEIN, MOUSE; ARGINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL STRAIN; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; DISEASE COURSE; HISTOPATHOLOGY; IMMUNITY; KINETICS; LUNG PARENCHYMA; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MORTALITY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN EXPRESSION; TUBERCULOSIS; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG ALVEOLUS; LUNG TUBERCULOSIS; MACROPHAGE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; SURVIVAL ANALYSIS; T LYMPHOCYTE;

BACTERIA (MICROORGANISMS); MUS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ARGINASE; BACTERIAL LOAD; CELL PROLIFERATION; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE SYNTHASE TYPE II; PULMONARY ALVEOLI; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TUBERCULOSIS, PULMONARY;

EID: 84925424762     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121070     Document Type: Article

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