Membrane-active macromolecules resensitize NDM-1 gram-negative clinical isolates to tetracycline antibiotics

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Uppu, Divakara S S M ^a   Manjunath, Goutham B ^a   Yarlagadda, Venkateswarlu ^a   Kaviyil, Jyothi E ^b   Ravikumar, Raju ^b   Paramanandham, Krishnamoorthy ^c   Shome, Bibek R ^c   Haldar, Jayanta ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^b NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^c ICAR NATIONAL INSTITUTE OF VETERINARY EPIDEMIOLOGY AND DISEASE INFORMATICS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXYCYCLINE; MINOCYCLINE; TETRACYCLINE DERIVATIVE; BETA LACTAMASE; BETA-LACTAMASE NDM-1; MALEIMIDE DERIVATIVE; TETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL LOAD; BACTERIAL MEMBRANE; BACTERIUM ISOLATION; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG UPTAKE; ESCHERICHIA COLI; FEMALE; IN VIVO STUDY; KLEBSIELLA PNEUMONIAE; LD 50; MACROMOLECULE; MEMBRANE ACTIVE MACROMOLECULE; MEMBRANE PERMEABILITY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; TOXICITY TESTING; ANIMAL; ANTIBIOTIC RESISTANCE; CELL MEMBRANE; CHEMISTRY; DRUG EFFECTS; DRUG POTENTIATION; HUMAN; KLEBSIELLA INFECTIONS; MEMBRANE POTENTIAL; METABOLISM; MICROBIOLOGY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MUS; NEGIBACTERIA;

ANIMALS; BETA-LACTAMASES; CELL MEMBRANE; DRUG RESISTANCE, BACTERIAL; DRUG SYNERGISM; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALEIMIDES; MEMBRANE POTENTIALS; MICE; TETRACYCLINE;

EID: 84925400750     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119422     Document Type: Article

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