Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-terminal half of dengue virus NS2A involved in viral RNA replication and virus assembly and secretion

Journal of Virology

Volumn 89, Issue 8, 2015, Pages 4281-4295

  Wu, Ren Huang ^a,b   Tsai, Ming Han ^a   Chao, Day Yu ^c   Yueh, Andrew ^a,b  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 2A; UNCLASSIFIED DRUG; VIRUS RNA; NS2A PROTEIN, DENGUE VIRUS TYPE 2; PRIMER DNA; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENGUE VIRUS; HEK293 CELL LINE; NONHUMAN; PRIORITY JOURNAL; REVERTANT; RNA REPLICATION; VIRUS ASSEMBLY; VIRUS INFECTIVITY; VIRUS LIKE AGENT; VIRUS MUTANT; VIRUS RELEASE; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; VIRAL PLAQUE ASSAY; VIRUS REPLICATION; WESTERN BLOTTING;

DENGUE VIRUS;

BASE SEQUENCE; BLOTTING, WESTERN; DENGUE VIRUS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS, DNA; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PLAQUE ASSAY; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 84925400665     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03011-14     Document Type: Article

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