Disruption of type I interferon signaling by the nonstructural protein of severe fever with thrombocytopenia syndrome virus via the hijacking of STAT2 and STAT1 into inclusion bodies

Journal of Virology

Volumn 89, Issue 8, 2015, Pages 4227-4236

  Ning, Yun Jia ^a   Feng, Kuan ^a   Min, Yuan Qin ^b   Cao, Wu Chun ^c   Wang, Manli ^a   Deng, Fei ^a   Hu, Zhihong ^a   Wang, Hualin ^a  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

^b WUHAN UNIVERSITY   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DNA; INTERFERON; NUCLEOCAPSID PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; VIRUS PROTEIN; LUCIFERASE; MONOCLONAL ANTIBODY; STAT1 PROTEIN, HUMAN; STAT2 PROTEIN, HUMAN; VIRAL PROTEIN;

ANIMAL CELL; ARTICLE; BUNYAVIRIDAE; CELL INCLUSION; CELL NUCLEUS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA BINDING; GENE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INHIBITION KINETICS; INTERFERON STIMULATED GENE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS; SIGNAL TRANSDUCTION; VIRUS INHIBITION; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; METABOLISM; PHLEBOVIRUS; PHYSIOLOGY; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ORTHOBUNYAVIRUS;

ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; GENES, REPORTER; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOPRECIPITATION; INCLUSION BODIES; INTERFERON TYPE I; LUCIFERASES; MICROSCOPY, CONFOCAL; PHLEBOVIRUS; PROTEIN INTERACTION MAPPING; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84925400661     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00154-15     Document Type: Article

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