Thermodynamic phase behaviour of indomethacin/PLGA formulations

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 93, Issue , 2015, Pages 88-94

  Prudic, Anke ^a   Lesniak, Anna Katharina ^a   Ji, Yuanhui ^a   Sadowski, Gabriele ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Copolymer; Indomethacin; Kwei equation; PC SAFT; Phase behaviour; PLGA; Poorly soluble pharmaceutical; Thermodynamic model

Indexed keywords

INDOMETACIN; POLYGLACTIN; RESOMER; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; BALL MILLING; CHEMICAL COMPOSITION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STRUCTURE; GLASS TRANSITION TEMPERATURE; MEASUREMENT ACCURACY; MOLECULAR WEIGHT; PERTURBED CHAIN STATISTICAL ASSOCIATING FLUID THEORY; ROOM TEMPERATURE; THEORETICAL MODEL; THERMODYNAMICS; THERMOSTABILITY; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; MEDICINAL CHEMISTRY; PHARMACEUTICS; PHASE TRANSITION; PROCEDURES; SOLUBILITY; TRANSITION TEMPERATURE;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; INDOMETHACIN; LACTIC ACID; MODELS, CHEMICAL; MOLECULAR WEIGHT; PHASE TRANSITION; POLYGLYCOLIC ACID; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THERMODYNAMICS; TRANSITION TEMPERATURE;

EID: 84925372503     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.01.029     Document Type: Article

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