Modulation of stress versus time product during mechanical ventilation influences inflammation as well as alveolar epithelial and endothelial response in rats

Anesthesiology

Volumn 122, Issue 1, 2015, Pages 106-116

  Spieth, Peter M ^a   Silva, Pedro L ^b   Garcia, Cristiane S N B ^b,c   Ornellas, Debora S ^b   Samary, Cynthia S ^b   Moraes, Lillian ^b   Bentes, Maira ^b   Morales, Marcelo M ^b   Kasper, Michael ^d   Güldner, Andreas ^a   Huhle, Robert ^a   Koch, Thea ^a   Pelosi, Paolo ^e   De Abreu, Marcelo Gama ^a   Rocco, Patricia R M ^b  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Phytotech Department   (Brazil)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MESSENGER RNA; VASCULAR CELL ADHESION MOLECULE 1; BIOLOGICAL MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; ENDOTHELIUM INJURY; GAS EXCHANGE; GENE EXPRESSION; LUNG ALVEOLUS EPITHELIUM CELL; LUNG EDEMA; LUNG PARENCHYMA; MALE; MECHANICAL STRESS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STRESS VERSUS TIME PRODUCT; ADVERSE EFFECTS; ANIMAL; BLOOD; COMPARATIVE STUDY; DISEASE MODEL; ENDOTHELIUM; INFLAMMATION; LUNG ALVEOLUS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROCEDURES; RESPIRATORY TRACT MUCOSA; TIME; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; ENDOTHELIUM; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; PULMONARY ALVEOLI; RATS; RATS, WISTAR; RESPIRATION, ARTIFICIAL; RESPIRATORY MUCOSA; STRESS, PHYSIOLOGICAL; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84925366160     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000415     Document Type: Article

References (32)

1. Tremblay LN, Slutsky AS: Ventilator-induced lung injury: From the bench to the bedside. Intensive Care Med 2006; 32: 24-33
2. The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342: 1301-8
3. Wolthuis EK, Choi G, Dessing MC, Bresser P, Lutter R, Dzoljic M, van der Poll T, Vroom MB, Hollmann M, Schultz MJ: Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. Anesthesi ology 2008; 108: 46-54
4. Determann RM, Royakkers A, Wolthuis EK, Vlaar AP, Choi G, Paulus F, Hofstra JJ, de Graaff MJ, Korevaar JC, Schultz MJ: Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: A preventive randomized controlled trial. Crit Care 2010; 14: R1
5. Protti A, Cressoni M, Santini A, Langer T, Mietto C, Febres D, Chierichetti M, Coppola S, Conte G, Gatti S, Leopardi O, Masson S, Lombardi L, Lazzerini M, Rampoldi E, Cadringher P, Gattinoni L: Lung stress and strain during mechanical ventilation: Any safe threshold? Am J Respir Crit Care Med 2011; 183: 1354-62
6. Y errapureddy A, Tobias J, Margulies SS: Cyclic stretch magnitude and duration affect rat alveolar epithelial gene expression. Cell Physiol Biochem 2010; 25: 113-22
7. Gama de Abreu M, Quelhas AD, Spieth P, Brauer G, Knels L, Kasper M, Pino AV, Bleyl JU, Hubler M, Bozza F, Salluh J, Kuhlisch E, Giannella-Neto A, Koch T: Comparative effects of vaporized perfluorohexane and partial liquid ventilation in oleic acid-induced lung injury. Anesthesi ology 2006; 104: 278-89
8. Scherle W: A simple method for volumetry of organs in quantitative stereology. Mikroskopie 1970; 26: 57-60
9. Spieth PM, Knels L, Kasper M, Domingues Quelhas A, Wiedemann B, Lupp A, Hübler M, Neto AG, Gianella Neto A, Koch T, Gama de Abreu M: Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury. Intensive Care Med 2007; 33: 308-14
10. Peterson BT, Collins ML, Gray LD, Azghani AO: Aerosolized Pseudomonas elastase and lung fluid balance in anesthetized sheep. J Appl Physiol (1985) 1992; 72: 1927-33
11. Santos CL, Moraes L, Santos RS, Oliveira MG, Silva JD, Maron-Gutierrez T, Ornellas DS, Morales MM, Capelozzi VL, Jamel N, Pelosi P, Rocco PR, Garcia CS: Effects of different tidal volumes in pulmonary and extrapulmonary lung injury with or without intraabdominal hypertension. Intensive Care Med 2012; 38: 499-508
12. Riva DR, Oliveira MB, Rzezinski AF, Rangel G, Capelozzi VL, Zin WA, Morales MM, Pelosi P, Rocco PR: Recruitment maneuver in pulmonary and extrapulmonary experimental acute lung injury. Crit Care Med 2008; 36: 1900-8
13. Garcia CS, Abreu SC, Soares RM, Prota LF, Figueira RC, Morales MM, Capelozzi VL, Zin WA, Rocco PR: Pulmonary morphofunctional effects of mechanical ventilation with high inspiratory air flow. Crit Care Med 2008; 36: 232-9
14. Fanelli V, Mascia L, Puntorieri V, Assenzio B, Elia V, Fornaro G, Martin EL, Bosco M, Delsedime L, Fiore T, Grasso S, Ranieri VM: Pulmonary atelectasis during low stretch ventilation: "Open lung" versus "lung rest" strategy. Crit Care Med 2009; 37: 1046-53
15. Krebs J, Pelosi P, Tsagogiorgas C, Haas J, Yard B, Rocco PR, Luecke T: Time course of lung inflammatory and fibrogenic responses during protective mechanical ventilation in healthy rats. Respir Physiol Neurobiol 2011; 178: 323-8
16. Sugahara K, Iyama K, Sano K, Kuroki Y, Akino T, Matsumoto M: Overexpression of surfactant protein SP-A, SP-B, and SP-C mRNA in rat lungs with lipopolysaccharide-induced injury. Lab Invest 1996; 74: 209-20
17. Y amakawa N, Uchida T, Matthay MA, Makita K: Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 2011; 300: L516-25
18. Miyao N, Suzuki Y, Takeshita K, Kudo H, Ishii M, Hiraoka R, Nishio K, Tamatani T, Sakamoto S, Suematsu M, Tsumura H, Ishizaka A, Yamaguchi K: Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2006; 290: L1059-68
19. Y oshikawa S, King JA, Lausch RN, Penton AM, Eyal FG, Parker JC: Acute ventilator-induced vascular permeability and cytokine responses in isolated and in situ mouse lungs. J Appl Physiol (1985) 2004; 97: 2190-9
20. Wilson MR, Choudhury S, Goddard ME, O'Dea KP, Nicholson AG, Takata M: High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol (1985) 2003; 95: 1385-93
21. Silva PL, Cruz FF, Fujisaki LC, Oliveira GP, Samary CS, Ornellas DS, Maron-Gutierrez T, Rocha NN, Goldenberg R, Garcia CS, Morales MM, Capelozzi VL, Gama de Abreu M, Pelosi P, Rocco PR: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury. Crit Care 2010; 14: R114
22. Plataki M, Hubmayr RD: The physical basis of ventilatorinduced lung injury. Expert Rev Respir Med 2010; 4: 373-85
23. Broccard AF, Hotchkiss JR, Suzuki S, Olson D, Marini JJ: Effects of mean airway pressure and tidal excursion on lung injury induced by mechanical ventilation in an isolated perfused rabbit lung model. Crit Care Med 1999; 27: 1533-41
24. Roan E, Waters CM: What do we know about mechanical strain in lung alveoli? Am J Physiol Lung Cell Mol Physiol 2011; 301: L625-35
25. Cannon D, Kalso EJ, Sykes MK: Effects of the pattern of ventilation and of an increase in cardiac output on the distribution of blood flow to a hypoxic lung lobe. Br J Anaesth 1988; 60: 81-90
26. Broccard AF, Hotchkiss JR, Kuwayama N, Olson DA, Jamal S, Wangensteen DO, Marini JJ: Consequences of vascular flow on lung injury induced by mechanical ventilation. Am J Respir Crit Care Med 1998; 157(6 Pt 1): 1935-42
27. Carvalho AR, Spieth PM, Güldner A, Cuevas M, Carvalho NC, Beda A, Spieth S, Stroczynski C, Wiedemann B, Koch T, Pelosi P, de Abreu MG: Distribution of regional lung aeration and perfusion during conventional and noisy pressure support ventilation in experimental lung injury. J Appl Physiol (1985) 2011; 110: 1083-92
28. Spieth PM, Carvalho AR, Güldner A, Kasper M, Schubert R, Carvalho NC, Beda A, Dassow C, Uhlig S, Koch T, Pelosi P, Gama de Abreu M: Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support. Crit Care Med 2011; 39: 746-55
29. Gattinoni L, Carlesso E, Caironi P: Stress and strain within the lung. Curr Opin Crit Care 2012; 18: 42-7
30. Rocco PR, Dos Santos C, Pelosi P: Pathophysiology of ventilator-associated lung injury. Curr Opin Anaesthesiol 2012; 25: 123-30
31. Protti A, Andreis DT, Monti M, Santini A, Sparacino CC, Langer T, Votta E, Gatti S, Lombardi L, Leopardi O, Masson S, Cressoni M, Gattinoni L: Lung stress and strain during mechanical ventilation: Any difference between statics and dynamics? Crit Care Med 2013; 41: 1046-55
32. Mead J, Takishima T, Leith D: Stress distribution in lungs: A model of pulmonary elasticity. J Appl Physiol 1970; 28: 596-608