Comparative evaluation of the protective efficacy of two formulations of a recombinant Chlamydia abortus subunit candidate vaccine in a mouse model

Vaccine

Volumn 33, Issue 15, 2015, Pages 1865-1872

  Pan, Qing ^a,b   Pais, Roshan ^a   Ohandjo, Adaugo ^a   He, Cheng ^b   He, Qing ^a   Omosun, Yusuf ^a   Igietseme, J U ^c   Eko, F O ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Chlamydia abortus; Cross protection; Immunity; Pmp18D; Vaccine delivery

Indexed keywords

B7 ANTIGEN; BACTERIAL VACCINE; CD40 ANTIGEN; CD86 ANTIGEN; CRYOPYRIN; FLT3 LIGAND; GAMMA INTERFERON; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2C ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; RECOMBINANT CHLAMYDIA ABORTUS SUBUNIT VACCINE; SUBUNIT VACCINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BACTERIUM ANTIBODY; CPG-OLIGONUCLEOTIDE; IMMUNOLOGICAL ADJUVANT; OLIGODEOXYRIBONUCLEOTIDE; RECOMBINANT VACCINE; TOLL LIKE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CHLAMYDIASIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; FEMALE; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; UPREGULATION; VACCINATION; VIBRIO CHOLERAE; ANIMAL; C57BL MOUSE; CHLAMYDIA; CHLAMYDIA INFECTIONS; COMPARATIVE STUDY; CROSS PROTECTION; DENDRITIC CELL; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; T LYMPHOCYTE; VAGINA;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; CHLAMYDIA; CHLAMYDIA INFECTIONS; CROSS PROTECTION; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNITY, INNATE; MICE; MICE, INBRED C57BL; OLIGODEOXYRIBONUCLEOTIDES; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC; VAGINA; VIBRIO CHOLERAE;

EID: 84925338215     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.02.007     Document Type: Article

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