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Volumn 240, Issue 3, 2015, Pages 392-399

Modulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells

Author keywords

glioblastoma; p53; radiosensitivity; Sonic hedgehog; WOX1

Indexed keywords

CYCLOPAMINE; OXIDOREDUCTASE; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; WW DOMAIN CONTAINING OXIDOREDUCTASE; ZERUMBONE; GLI1 PROTEIN, HUMAN; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN P53; SESQUITERPENE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; VERATRUM ALKALOID; WWOX PROTEIN, HUMAN;

EID: 84925310869     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214565989     Document Type: Article
Times cited : (22)

References (30)
  • 1
    • 1042301341 scopus 로고    scopus 로고
    • Factors influencing survival in high-grade gliomas
    • Buckner JC.Factors influencing survival in high-grade gliomas.Semin Oncol. 2003;30:10-4
    • (2003) Semin Oncol , vol.30 , pp. 10-14
    • Buckner, J.C.1
  • 3
    • 0033754122 scopus 로고    scopus 로고
    • The sonic hedgehog-patched-gli pathway in human development and disease
    • Villavicencio EH,Walterhouse DO,Iannaccone PM.The sonic hedgehog-patched-gli pathway in human development and disease.Am J Hum Genet. 2000;67:1047-54
    • (2000) Am J Hum Genet , vol.67 , pp. 1047-1054
    • Villavicencio, E.H.1    Walterhouse, D.O.2    Iannaccone, P.M.3
  • 4
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nusslein-Volhard C,Wieschaus E.Mutations affecting segment number and polarity in Drosophila.Nature. 1980;287:795-801
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 5
    • 0030913610 scopus 로고    scopus 로고
    • Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice
    • Platt KA,Michaud J,Joyner AL.Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice.Mech Dev. 1997;62:121-35
    • (1997) Mech Dev , vol.62 , pp. 121-135
    • Platt, K.A.1    Michaud, J.2    Joyner, A.L.3
  • 6
    • 79957566966 scopus 로고    scopus 로고
    • Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner
    • Chen YJ,Lin CP,Hsu ML,Shieh HR,Chao NK,Chao KS.Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner.Int J Radiat Oncol Biol Phys. 2011;80:851-9
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 851-859
    • Chen, Y.J.1    Lin, C.P.2    Hsu, M.L.3    Shieh, H.R.4    Chao, N.K.5    Chao, K.S.6
  • 8
    • 33845879138 scopus 로고    scopus 로고
    • WW domain-containing oxidoreductase: a candidate tumor suppressor
    • Chang NS,Hsu LJ,Lin YS,Lai FJ,Sheu HM.WW domain-containing oxidoreductase: a candidate tumor suppressor.Trends Mol Med. 2007;13:12-22
    • (2007) Trends Mol Med , vol.13 , pp. 12-22
    • Chang, N.S.1    Hsu, L.J.2    Lin, Y.S.3    Lai, F.J.4    Sheu, H.M.5
  • 10
    • 70350463840 scopus 로고    scopus 로고
    • WWOX: its genomics, partners, and functions
    • Del Mare S,Salah Z,Aqeilan RI.WWOX: its genomics, partners, and functions.J Cell Biochem. 2009;108:737-45
    • (2009) J Cell Biochem , vol.108 , pp. 737-745
    • Del Mare, S.1    Salah, Z.2    Aqeilan, R.I.3
  • 17
    • 44449097274 scopus 로고    scopus 로고
    • Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells
    • Nakayama S,Semba S,Maeda N,Aqeilan RI,Huebner K,Yokozaki H.Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.Cancer Sci. 2008;99:1370-6
    • (2008) Cancer Sci , vol.99 , pp. 1370-1376
    • Nakayama, S.1    Semba, S.2    Maeda, N.3    Aqeilan, R.I.4    Huebner, K.5    Yokozaki, H.6
  • 18
    • 84866156432 scopus 로고    scopus 로고
    • Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53
    • Chiang MF,Yeh ST,Liao HF,Chang NS,Chen YJ.Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53.Biomed Pharmacother. 2012;66:433-8
    • (2012) Biomed Pharmacother , vol.66 , pp. 433-438
    • Chiang, M.F.1    Yeh, S.T.2    Liao, H.F.3    Chang, N.S.4    Chen, Y.J.5
  • 19
    • 0030448650 scopus 로고    scopus 로고
    • Identification of a novel p53 functional domain that is necessary for efficient growth suppression
    • Walker KK,Levine AJ.Identification of a novel p53 functional domain that is necessary for efficient growth suppression.Proc Natl Acad Sci U S A. 1996;93:15335-40
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 15335-15340
    • Walker, K.K.1    Levine, A.J.2
  • 20
    • 0035793612 scopus 로고    scopus 로고
    • Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
    • Chang NS,Pratt N,Heath J,Schultz L,Sleve D,Carey GB,Zevotek N.Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.J Biol Chem. 2001;276:3361-70
    • (2001) J Biol Chem , vol.276 , pp. 3361-3370
    • Chang, N.S.1    Pratt, N.2    Heath, J.3    Schultz, L.4    Sleve, D.5    Carey, G.B.6    Zevotek, N.7
  • 21
    • 30044438229 scopus 로고    scopus 로고
    • WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53
    • Chang NS,Doherty J,Ensign A,Schultz L,Hsu LJ,Hong Q.WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.J Biol Chem. 2005;280:43100-8
    • (2005) J Biol Chem , vol.280 , pp. 43100-43108
    • Chang, N.S.1    Doherty, J.2    Ensign, A.3    Schultz, L.4    Hsu, L.J.5    Hong, Q.6
  • 22
    • 78650014447 scopus 로고    scopus 로고
    • Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas
    • Squatrito M,Brennan CW,Helmy K,Huse JT,Petrini JH,Holland EC.Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.Cancer Cell. 2010;18:619-29
    • (2010) Cancer Cell , vol.18 , pp. 619-629
    • Squatrito, M.1    Brennan, C.W.2    Helmy, K.3    Huse, J.T.4    Petrini, J.H.5    Holland, E.C.6
  • 23
    • 23844466267 scopus 로고    scopus 로고
    • WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo
    • Lai FJ,Cheng CL,Chen ST,Wu CH,Hsu LJ,Lee JY,Chao SC,Sheen MC,Shen CL,Chang NS,Sheu HM.WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo.Clin Cancer Res. 2005;11:5769-77
    • (2005) Clin Cancer Res , vol.11 , pp. 5769-5777
    • Lai, F.J.1    Cheng, C.L.2    Chen, S.T.3    Wu, C.H.4    Hsu, L.J.5    Lee, J.Y.6    Chao, S.C.7    Sheen, M.C.8    Shen, C.L.9    Chang, N.S.10    Sheu, H.M.11
  • 25
    • 0038322051 scopus 로고    scopus 로고
    • JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis
    • Chang NS,Doherty J,Ensign A.JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis.J Biol Chem. 2003;278:9195-202
    • (2003) J Biol Chem , vol.278 , pp. 9195-9202
    • Chang, N.S.1    Doherty, J.2    Ensign, A.3
  • 26
    • 84883382309 scopus 로고    scopus 로고
    • Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastresophageal junction
    • Clemons N, Phillips W, Lord RV. Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastresophageal junction. Cancer Biol Ther 2013;14: 782--95.
    • (2013) Cancer Biol Ther , vol.14 , pp. 782-795
    • Clemons, N.1    Phillips, W.2    Lord, R.V.3
  • 27
    • 84893539239 scopus 로고    scopus 로고
    • The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma
    • Justilien V,Walsh MP,Ali SA,Thompson EA,Murray NR,Fields AP.The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma.Cancer Cell. 2014;25:139-51
    • (2014) Cancer Cell , vol.25 , pp. 139-151
    • Justilien, V.1    Walsh, M.P.2    Ali, S.A.3    Thompson, E.A.4    Murray, N.R.5    Fields, A.P.6
  • 29
    • 84880867961 scopus 로고    scopus 로고
    • Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts
    • Huerta S,Gao X,Dineen S,Kapur P,Saha D,Meyer J.Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts.Surgery. 2013;154:143-51
    • (2013) Surgery , vol.154 , pp. 143-151
    • Huerta, S.1    Gao, X.2    Dineen, S.3    Kapur, P.4    Saha, D.5    Meyer, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.