Cationic amphipathic peptides KT2 and RT2 are taken up into bacterial cells and kill planktonic and biofilm bacteria

Biochimica et Biophysica Acta - Biomembranes

Volumn 1848, Issue 6, 2015, Pages 1352-1358

  Anunthawan, Thitiporn ^a,b   De La Fuente Núñez, César ^c   Hancock, Robert E W ^c   Klaynongsruang, Sompong ^a,b  

^a Khon Kaen University   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antibacterial mechanism; Antibacterial peptide; Antibiofilm peptide; DNA binding; KT2; RT2

Indexed keywords

ANTIINFECTIVE AGENT; BUFORIN II; KT2 PEPTIDE; MEMBRANE PHOSPHOLIPID; POLYPEPTIDE ANTIBIOTIC AGENT; RT2 PEPTIDE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CATION; CATIONIC AMPHIPATHIC PEPTIDE KT2; CATIONIC AMPHIPATHIC PEPTIDE RT2; DNA; LIPOPOLYSACCHARIDE; LIPOSOME; MEMBRANE LIPID; TRYPTOPHAN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BACTERIUM IDENTIFICATION; BINDING AFFINITY; BINDING SITE; BIOFILM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA BINDING; DRUG DNA BINDING; DRUG EFFECT; ESCHERICHIA COLI O157; GROWTH INHIBITION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; CELL MEMBRANE; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; ESCHERICHIA COLI; KINETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; PLANKTON;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA;

ANTIMICROBIAL CATIONIC PEPTIDES; BIOFILMS; CATIONS; CELL MEMBRANE; DNA; ESCHERICHIA COLI; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; LIPOPOLYSACCHARIDES; LIPOSOMES; MEMBRANE LIPIDS; MICROBIAL SENSITIVITY TESTS; PLANKTON; TRYPTOPHAN;

EID: 84925310846     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2015.02.021     Document Type: Article

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