Multiple Combination Therapies Involving Blockade of ICOS/B7RP-1 Costimulation Facilitate Long-Term Islet Allograft Survival

American Journal of Transplantation

Volumn 4, Issue 4, 2004, Pages 526-536

  Nanji, Sulaiman A ^a   Hancock, Wayne W ^b   Anderson, Colin C ^a   Adams, Andrew B ^c   Luo, Bin ^a   Schur, Colleen D ^a   Pawlick, Rena L ^a   Wang, Liqing ^b   Coyle, Anthony J ^d   Larsen, Christian P ^c   Shapiro, A M James ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Costimulation; Immunosuppression; Islet; Tolerance; Transplantation

Indexed keywords

B7 RELATED PROTEIN 1; CD40 LIGAND MONOCLONAL ANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INDUCIBLE COSTIMULATOR MOLECULE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ICOS; PROTEIN; RAPAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGICAL TOLERANCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; ORGAN DONOR; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TRANSPLANTATION TOLERANCE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; ISLETS OF LANGERHANS TRANSPLANTATION; LIGANDS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; SIROLIMUS; T-LYMPHOCYTES; TIME FACTORS;

EID: 11144354562     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2004.00384.x     Document Type: Article

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