Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts

American Journal of Transplantation

Volumn 9, Issue 1, 2009, Pages 64-73

  Schenk, A D ^a,b   Gorbacheva, V ^b   Rabant, M ^b,c   Fairchild, R L ^a,b   Valujskikh, A ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Costimulation; Effector mechanisms; Memory CD8+ T cells; Proliferation; Trafficking

Indexed keywords

B7 ANTIGEN; B7 RELATED PROTEIN 1; CD28 ANTIGEN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN INDUCIBLE COSTIMULATORY MOLECULE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIVISION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEART TRANSPLANTATION; ISOGRAFT; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MALE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; RECEPTOR BLOCKING; RECEPTOR UPREGULATION;

ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BONE MARROW CELLS; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GENES, MHC CLASS I; HEART TRANSPLANTATION; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 58049211975     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02460.x     Document Type: Article

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