MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14)

Tumor Biology

Volumn 35, Issue 12, 2014, Pages 12593-12599

  Zhang, Tian ^a   Sun, Quanquan ^a   Liu, Tongxin ^a   Chen, Jiarong ^a   Du, Shasha ^a   Ren, Chen ^a   Liao, Guixiang ^a   Yuan, Yawei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

MicroRNA; MiR 451; Nasopharyngeal carcinoma; RAB14; Radiosensitivity

Indexed keywords

CASPASE 3; HISTONE H2AX; MICRORNA; MICRORNA 451; RAS PROTEIN; RAS RELATED PROTEIN 14; TUMOR PROTEIN; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MIRN451 MICRORNA, HUMAN; RAB PROTEIN; RAB14 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; COLONY FORMATION; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IONIZING RADIATION; LUCIFERASE ASSAY; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; WESTERN BLOTTING; 3' UNTRANSLATED REGION; BINDING SITE; CHEMISTRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; NASOPHARYNX TUMOR; NUCLEOTIDE SEQUENCE; RADIATION DOSE; RADIATION RESPONSE; RNA INTERFERENCE; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NASOPHARYNGEAL NEOPLASMS; RAB GTP-BINDING PROTEINS; RADIATION TOLERANCE; RNA INTERFERENCE;

EID: 84925283415     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2581-x     Document Type: Article

References (30)

1. Fahraeus R, Fu HL, Ernberg I, Finke J, Rowe M, Klein G, et al. Expression of Epstein-Barr virus-encoded proteins in nasopharyngeal carcinoma. Int J Cancer. 1988;42:329–38.
2. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63:11–30.
3. Zongaro S, Hukema R, D’Antoni S, Davidovic L, Barbry P, Catania MV, et al. The 3′ UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse. Hum Mol Genet. 2013;22:1971–82.
4. Minguzzi S, Selcuklu SD, Spillane C, Parle-McDermott A. An NTD-associated polymorphism in the 3′ UTR of MTHFD1L can affect disease risk by altering miRNA binding. Hum Mutat. 2014;35:96–104.
5. Duan W, Xu Y, Dong Y, Cao L, Tong J, Zhou X. Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway. J Radiat Res. 2013;54:611–9.
6. Lin J, Liu C, Gao F, Mitchel RE, Zhao L, Yang Y, et al. MiR-200c enhances radiosensitivity of human breast cancer cells. J Cell Biochem. 2013;114:606–15.
7. Zhang X, Sun K, Lei S, Zhong Y, Deng H, Ou W, Wu C. [Anti-microRNA-221 enhances radiosensitivity of colorectal carcinoma cells by up-regulating PTEN]. Nan Fang Yi Ke Da Xue Xue Bao. 2013;33:728–732.
8. Cheng L, Yang T, Kuang Y, Kong B, Yu S, Shu H, et al. MicroRNA-23a promotes neuroblastoma cell metastasis by targeting CDH1. Oncol Lett. 2014;7:839–45.
9. Sakai H, Sato A, Aihara Y, Ikarashi Y, Midorikawa Y, Kracht M, Nakagama H, Okamoto K. MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells. Cancer Sci. 2014;105(4):425–30. doi:10.1111/cas.12380.
10. Zhang J, Cheng C, Yuan X, He JT, Pan QH, Sun FY. MicroRNA-155 acts as an oncogene by targeting the tumor protein 53-induced nuclear protein 1 in esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2014;7:602–10.
11. Qu C, Liang Z, Huang J, Zhao R, Su C, Wang S, et al. MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. Cell Cycle. 2012;11:785–96.
12. Li G, Liu Y, Su Z, Ren S, Zhu G, Tian Y, Qiu Y. MicroRNA-324-3p regulates nasopharyngeal carcinoma radioresistance by directly targeting WNT2B. Eur J Cancer. 2013;49(11):2596–607. doi:10.1016/j.ejca.2013.03.001.
13. Fan F, Lei C, Dong-Liang L, Peng S. Inflammatory myofibroblastic tumor mimicking malignant meningioma in the middle cranial fossa: a case report. Chin Med Sci J. 2012;27:185–187.
14. Liu N, Jiang N, Guo R, Jiang W, He QM, Xu YF, et al. MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma. Mol Cancer. 2013;12:123.
15. Zhai X, Yang Y, Wan J, Zhu R, Wu Y. Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol Rep. 2013;30:2983–91.
16. Zafar F, Seidler SB, Kronenberg A, Schild D, Wiese C. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. Radiat Res. 2010;173:27–39.
17. Moncharmont C, Levy A, Gilormini M, Bertrand G, Chargari C, Alphonse G, et al. Targeting a cornerstone of radiation resistance: cancer stem cell. Cancer Lett. 2012;322:139–47.
18. Shi L, Zhang S, Wu H, Zhang L, Dai X, Hu J, et al. MiR-200c increases the radiosensitivity of non-small-cell lung cancer cell line A549 by targeting VEGF-VEGFR2 pathway. PLoS One. 2013;8:e78344.
19. Magnon C, Opolon P, Ricard M, Connault E, Ardouin P, Galaup A, et al. Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1alpha-mediated tumor apoptotic switch. J Clin Invest. 2007;117:1844–55.
20. Wang Y, Yin W, Zhu X. Blocked autophagy enhances radiosensitivity of nasopharyngeal carcinoma cell line CNE-2 in vitro. Acta Otolaryngol. 2014;134:105–10.
21. Zhao YX, Cheng C, Zhu F, Wu HG, Ren JH, Chen WH, et al. Suppression of low-dose hyper-radiosensitivity in human lung cancer cell line A549 by radiation-induced autophagy. J Huazhong Univ Sci Technol Med Sci. 2013;33:770–4.
22. Guo P, Lan J, Ge J, Nie Q, Guo L, Qiu Y, et al. MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated. Exp Cell Res. 2014;320:200–8.
23. Tian Y, Nan Y, Han L, Zhang A, Wang G, Jia Z, et al. MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. Int J Oncol. 2012;40:1105–12.
24. Bandres E, Bitarte N, Arias F, Agorreta J, Fortes P, Agirre X, et al. microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells. Clin Cancer Res. 2009;15:2281–90.
25. Xie Z, Chen G, Zhang X, Li D, Huang J, Yang C, et al. Salivary microRNAs as promising biomarkers for detection of esophageal cancer. PLoS One. 2013;8:e57502.
26. Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF, et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther. 2008;7:2152–9.
27. Godlewski J, Bronisz A, Nowicki MO, Chiocca EA, Lawler S. MicroRNA-451: a conditional switch controlling glioma cell proliferation and migration. Cell Cycle. 2010;9:2742–8.
28. Nan Y, Han L, Zhang A, Wang G, Jia Z, Yang Y, et al. MiRNA-451 plays a role as tumor suppressor in human glioma cells. Brain Res. 2010;1359:14–21.
29. Chen MB, Wei MX, Han JY, Wu XY, Li C, Wang J, et al. MicroRNA-451 regulates AMPK/mtTORC1 signaling and fascin1 expression in HT-29 colorectal cancer. Cell Signal. 2014;26:102–9.
30. Wang R, Wang ZX, Yang JS, Pan X, De W, Chen LB. MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). Oncogene. 2011;30:2644–58.