Predictive genetic testing for adult-onset disorders in minors: A critical analysis of the arguments for and against the 2013 ACMG guidelines

Clinical Genetics

Volumn 87, Issue 4, 2015, Pages 301-310

  Anderson, J A ^a,b   Hayeems, R Z ^a,c   Shuman, C ^a,b   Szego, M J ^b,d,e,f   Monfared, N ^a   Bowdin, S ^a,b   Zlotnik Shaul, R ^a,b   Meyn, M S ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ST JOSEPH S HEALTH CENTRE   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

Child; DNA ethics; Genetic predisposition to disease; Genetic testing ethics; Genetic testing standards; Genomics ethics; Genomics standards; Incidental findings; Sequence analysis

Indexed keywords

ADULT ONSET GENETIC DISORDER; CHILDHOOD DISEASE; CLINICAL PRACTICE; CONSENSUS; EXOME; FAMILY HISTORY; GENE SEQUENCE; GENETIC DISORDER; GENETIC SCREENING; GENOME; HUMAN; INCIDENTAL FINDING; INFORMED CONSENT; MINOR (PERSON); PRACTICE GUIDELINE; PREDICTIVE VALUE; PRIORITY JOURNAL; PUBLICATION; REVIEW; RISK ASSESSMENT; ADULT; CHILD; DNA SEQUENCE; ETHICS; INTERPERSONAL COMMUNICATION; ONSET AGE; PROCEDURES; STANDARDS;

ADULT; AGE OF ONSET; CHILD; DISCLOSURE; GENETIC TESTING; GUIDELINES AS TOPIC; HUMANS; INCIDENTAL FINDINGS; MINORS; PREDICTIVE VALUE OF TESTS; SEQUENCE ANALYSIS, DNA;

EID: 84925247962     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/cge.12460     Document Type: Review

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