Successful antemortem diagnosis and treatment of pulmonary tumor thrombotic microangiopathy

Internal Medicine

Volumn 53, Issue 22, 2014, Pages 2595-2599

  Higo, Kenjuro ^a   Kubota, Kayoko ^a   Takeda, Ayano ^a   Higashi, Michiyo ^a   Ohishi, Mitsuru ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Bevacizumab; Imatinib; Pulmonary hypertension; Pulmonary tumor thrombotic microangiopathy

Indexed keywords

BEVACIZUMAB; BOSENTAN; BRAIN NATRIURETIC PEPTIDE; CISPLATIN; FUROSEMIDE; GIMERACIL PLUS OTERACIL POTASSIUM PLUS TEGAFUR; IMATINIB; PLATELET DERIVED GROWTH FACTOR; SPIRONOLACTONE; TADALAFIL; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

ADENOCARCINOMA; ADULT; ARTICLE; BLEEDING; CASE REPORT; COLORECTAL CANCER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COUGHING; DRUG DOSE INCREASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ELECTROCARDIOGRAPHY; GAS ANALYSIS; HEART CATHETERIZATION; HEART FAILURE; HUMAN; HYPOXEMIA; IMMUNOHISTOCHEMISTRY; LUNG ASPIRATION; LUNG TUMOR; MALE; MIDDLE AGED; PULMONARY HYPERTENSION; PULMONARY TUMOR THROMBOTIC MICROANGIOPATHY; THORAX RADIOGRAPHY; THROMBOTIC THROMBOCYTOPENIC PURPURA; TRANSTHORACIC ECHOCARDIOGRAPHY; AUTOPSY; COLORECTAL TUMOR; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; SECONDARY; THROMBOTIC MICROANGIOPATHIES;

ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AUTOPSY; COLORECTAL NEOPLASMS; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; THROMBOTIC MICROANGIOPATHIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84925197279     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.53.2379     Document Type: Article

References (14)

1. von Herbay A, Illes A, Waldherr R, Otto HF. Pulmonary tumor thrombotic microangiopathy with pulmonary hypertension. Cancer 66: 587-592, 1990.
2. Gavin MC, Morse D, Partridge AH, Levy BD, Loscalzo J. Clinical problem-solving. Breathless. N Engl J Med 366: 75-81, 2012.
3. Chinen K, Kazumoto T, Ohkura Y, Matsubara O, Tsushiya E. Pulmonary tumor thrombotic microangiopathy caused by a gastric carcinoma expressing vascular endothelial growth factor and tissue factor. Pathol Int 55: 27-31, 2005.
4. Miyano S, Izumi S, Takeda Y, et al. Pulmonary tumor thrombotic microangiopathy. J Clin Oncol 25: 597-599, 2007.
5. Kayatani H, Matsuo K, Ueda Y, et al. Pulmonary tumor thrombotic microangiopathy diagnosed antemortem and treated with combination chemotherapy. Intern Med 51: 2767-2770, 2012.
6. Masson RG, Ruggieri J. Pulmonary microvascular cytology. A new diagnosis application of the pulmonary artery catheter. Chest 88: 908-914, 1985.
7. Babar SI, Sobonya RE, Snyder LS. Pulmonary microvascular cytology for the diagnosis of pulmonary tumor embolism. West J Med 168: 47-50, 1998.
8. Okubo Y, Wakayama M, Kitahara K, et al. Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: morphometric and immunohistochemical analysis of six autopsy cases. Diagn Pathol 6: 27, 2011.
9. Chinen K, Tokuda Y, Fujiwara M, Fujioka Y. Pulmonary tumor thrombotic microangiopathy in patients with gastric carcinoma: an analysis of 6 autopsy cases and review of the literature. Pathol Res Pract 206: 682-689, 2010.
10. Uraga H, Fujii T, Kurosaki A, et al. Pulmonary tumor thrombotic microangiopathy: a clinical analysis of 30 autopsy cases. Intern Med 52: 1317-1323, 2013.
11. Yokomine T, Hirakawa H, Ozawa E, Shibata K, Nakayama T. Pulmonary thrombotic microangiopathy caused by gastric carcinoma. J Clin Pathol 63: 367-369, 2010.
12. Ogawa A, Yamadori I, Matsubara O, Matsubara H. Pulmonary tumor thrombotic microangiopathy with circulatory failure treated with imatinib. Intern Med 52: 1927-1930, 2013.
13. Geiger R, Berger RM, Hess J, Bogers AJ, Sharma HS, Mooi WJ. Enhanced expression of vascular endothelial growth factor in pulmonary plexogenic arteriopathy due to congenital heart disease. J Pathol 191: 202-207, 2000.
14. Garcia AA, Hirte H, Fleming G, et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol 26: 76-82, 2008.