Pulmonary tumor thrombotic microangiopathy with circulatory failure treated with imatinib

Internal Medicine

Volumn 52, Issue 17, 2013, Pages 1927-1930

  Ogawa, Aiko ^a   Yamadori, Ichiro ^a   Matsubara, Osamu ^b   Matsubara, Hiromi ^a  

^a NATIONAL HOSPITAL ORGANIZATION OKAYAMA MEDICAL CENTER   (Japan)

^b Hiratsuka Kyosai Hospital   (Japan)

Author keywords

Circulatory failure; Imatinib; Pulmonary tumor thrombotic microangiopathy; Treatment

Indexed keywords

BOSENTAN; BRAIN NATRIURETIC PEPTIDE; CATECHOLAMINE; DOBUTAMINE; DOPAMINE; FLUOROPYRIMIDINE; IMATINIB; PLATELET DERIVED GROWTH FACTOR; PROSTACYCLIN; VASCULOTROPIN;

ADENOCARCINOMA; ADULT; ARTICLE; CARDIOMEGALY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; DEATH; DUODENUM CARCINOMA; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FAINTNESS; FEMALE; FOLLOW UP; HEART CATHETERIZATION; HEART OUTPUT; HEMODYNAMICS; HUMAN; HUMAN TISSUE; ISCHEMIA; LUNG BIOPSY; LUNG PERFUSION; LUNG TUMOR; PLEURA EFFUSION; PULMONARY HYPERTENSION; SINUS TACHYCARDIA; STOMACH CARCINOMA; THORAX RADIOGRAPHY; THROMBOTIC THROMBOCYTOPENIC PURPURA;

ANTINEOPLASTIC AGENTS; BENZAMIDES; FEMALE; HUMANS; MIDDLE AGED; NEOPLASTIC CELLS, CIRCULATING; PIPERAZINES; PYRIMIDINES; THROMBOTIC MICROANGIOPATHIES;

EID: 84883413221     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.52.0718     Document Type: Article

References (7)

1. von Herbay A, Illes A, Waldherr R, et al. Pulmonary tumor thrombotic microangiopathy with pulmonary hypertension. Cancer 66: 587-592, 1990.
2. Pinckard JK, Wick MR. Tumor-related thrombotic pulmonary microangiopathy: review of pathologic findings and pathophysiologic mechanisms. Ann Diagn Pathol 4: 154-157, 2000.
3. Gavin MC, Morse D, Partridge AH, et al. Clinical problemsolving. Breathless. N Engl J Med 366: 75-81, 2012.
4. Ghofrani HA, Seeger W, Grimminger F. Imatinib for the treatment of pulmonary arterial hypertension. N Engl J Med 353: 1412-1413, 2005.
5. Ghofrani HA, Morrell NW, Hoeper MM, et al. Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med 182: 1171-1177, 2010.
6. Kim R, Emi M, Arihiro K, et al. Chemosensitization by STI571 targeting the platelet-derived growth factor/platelet-derived growth factor receptor-signaling pathway in the tumor progression and angiogenesis of gastric carcinoma. Cancer 103: 1800-1809, 2005.
7. Yokomine T, Hirakawa H, Ozawa E, et al. Pulmonary thrombotic microangiopathy caused by gastric carcinoma. J Clin Pathol 63: 367-369, 2010.