Selective breeding for high anxiety introduces a synonymous SNP that increases Neuropeptide S receptor activity

Journal of Neuroscience

Volumn 35, Issue 11, 2015, Pages 4599-4613

  Slattery, David A ^a   Naik, Roshan R ^a,b   Grund, Thomas ^a   Yen, Yi Chun ^b   Sartori, Simone B ^c   Füchsl, Andrea ^a   Finger, Beate C ^a   Elfving, Betina ^d   Nordemann, Uwe ^a   Guerrini, Remo ^e   Calo, Girolamo ^e   Wegener, Gregers ^d,g   Mathè, Aleksander A ^f   Singewald, Nicolas ^c   Czibere, Ludwig ^b   Landgraf, Rainer ^b   Neumann, Inga D ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c UNIVERSITY OF INNSBRUCK   (Austria)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY OF FERRARA   (Italy)

^f KAROLINSKA INSTITUTE   (Sweden)

^g NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Anxiety; Basolateral amygdala; Fear; Paraventricular nucleus; Promoter fragmentation

Indexed keywords

CYCLIC AMP; GENOMIC DNA; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; NEUROPEPTIDE S; TRANSCRIPTION FACTOR; G PROTEIN COUPLED RECEPTOR; NPSR1 PROTEIN, MOUSE;

ADULT; ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; COPY NUMBER VARIATION; ELEVATED PLUS MAZE TEST; GENE SEQUENCE; GENETIC TRANSCRIPTION; GENOTYPE; IMMUNOPRECIPITATION; LIGHT-DARK TEST; LOCOMOTION; LUCIFERASE ASSAY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WESTERN BLOTTING; ANIMAL; AUDITORY STIMULATION; BREEDING; FEAR; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PHYSIOLOGY; PROCEDURES; PSYCHOLOGY;

ACOUSTIC STIMULATION; ANIMALS; ANXIETY; BREEDING; FEAR; HEK293 CELLS; HUMANS; MALE; MICE; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84925115718     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4764-13.2015     Document Type: Article

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