Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats

Experimental Neurology

Volumn 267, Issue , 2015, Pages 135-142

  Gu, Xiaohuan ^a   Wei, Zheng Zachory ^a,b   Espinera, Alyssa ^a   Lee, Jin Hwan ^a   Ji, Xiaoya ^a   Wei, Ling ^a   Dix, Thomas A ^c,d   Yu, Shan Ping ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d JT Pharmaceuticals   (United States)

Author keywords

Brain protection; Cell death; Drug induced hypothermia; Functional recovery; Neonates; Traumatic brain injury

Indexed keywords

CASPASE 3; GELATINASE B; HPI 201; INTERLEUKIN 1BETA; INTERLEUKIN 6; NEURON SPECIFIC NUCLEAR PROTEIN; NEUROPROTECTIVE AGENT; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ABS-201; ENOLASE; OLIGOPEPTIDE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BODY TEMPERATURE; BRAIN CONTUSION; BRAIN PROTECTION; BRAIN TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; FUNCTIONAL STATUS; GENE EXPRESSION; INDUCED HYPOTHERMIA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; TRAUMATIC BRAIN INJURY; ANIMAL; BLOOD TESTIS BARRIER; BRAIN INJURIES; CONVALESCENCE; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TIME FACTOR; TUNEL ASSAY; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; BLOOD-TESTIS BARRIER; BODY TEMPERATURE; BRAIN INJURIES; CASPASE 3; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTHERMIA, INDUCED; IN SITU NICK-END LABELING; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 9; OLIGOPEPTIDES; PHOSPHOPYRUVATE HYDRATASE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84925091653     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.02.029     Document Type: Article

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