SCOPUS 정보 검색 플랫폼

Volumn 13, Issue 12, 2015, Pages 3803-3818

Design, synthesis and biological evaluation of 1-phenanthryl-tetrahydroisoquinoline derivatives as novel p21-activated kinase 4 (PAK4) inhibitors

(15) Song, Shuai a Li, Xiaodong b Guo, Jing a Hao, Chenzhou a Feng, Yan a Guo, Bingyu b Liu, Tongchao a Zhang, Qiaoling a Zhang, Zhen a Li, Ruijuan a Wang, Jian a Lin, Bin a Li, Feng b Zhao, Dongmei a Cheng, Maosheng a

a SHENYANG PHARMACEUTICAL UNIVERSITY (China)

b CHINA MEDICAL UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DISEASES; ENZYMES; SYNTHESIS (CHEMICAL);

ANTI-PROLIFERATIVE ACTIVITIES; BIOLOGICAL EVALUATION; INHIBITORY ACTIVITY; LEAD OPTIMIZATION; MOLECULAR MODELING STUDIES; P-21 ACTIVATED KINASE; SIGNALING PATHWAYS; STRUCTURAL BASIS;

CELL SIGNALING;

BENZYLISOQUINOLINE DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; HYDRASTINE; NOSCAPINE; P21 ACTIVATED KINASE; PHENANTHRENE DERIVATIVE; PROTEIN KINASE INHIBITOR; TETRAHYDROISOQUINOLINE DERIVATIVE;

ANTAGONISTS AND INHIBITORS; APOPTOSIS; BREAST TUMOR; CELL CYCLE; CELL MOTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; FEMALE; HUMAN; LENTIVIRINAE; MCF 7 CELL LINE; METABOLISM; PATHOLOGY; SYNTHESIS; TUMOR INVASION;

APOPTOSIS; BENZYLISOQUINOLINES; BREAST NEOPLASMS; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; DRUG DESIGN; FEMALE; HUMANS; INDICATORS AND REAGENTS; LENTIVIRUS; MCF-7 CELLS; MODELS, MOLECULAR; NEOPLASM INVASIVENESS; NOSCAPINE; P21-ACTIVATED KINASES; PHENANTHRENES; PROTEIN KINASE INHIBITORS; TETRAHYDROISOQUINOLINES;

EID: 84925068448 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c5ob00037h Document Type: Article

Times cited : (23)

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