메뉴 건너뛰기




Volumn 18, Issue 3, 2015, Pages 267-276

Investigation on metabolism of cisplatin resistant ovarian cancer using a genome scale metabolic model and microarray data

Author keywords

Cisplatin resistance; Drug target; Lactate; Metabolism; Microarray

Indexed keywords

5 HYDROXYTRYPTOPHAN; ADRENALIN; ALANINE; ASPARAGINE; BICARBONATE; BIOTIN; CDP DIACYLGLYCEROL SYNTHASE 1; CHECKPOINT KINASE 2; CHLORIDE; CISPLATIN; CYTIDINE DIPHOSPHATE DIGLYCERIDE; DICARBOXYLATE TRANSPORTER; DOPAMINE; FUMARATE HYDRATASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTAMINE; HISTAMINE; LACTIC ACID; MESSENGER RNA; NORADRENALIN; PANTOTHENIC ACID; PHOSPHATIDYLSERINE SYNTHASE; PHOSPHATIDYLSERINE SYNTHASE 1; PHOSPHORIBOSYLTRANSFERASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SERINE; THIOCTIC ACID; TYROSINE; UNCLASSIFIED DRUG; UREA;

EID: 84925063124     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (21)

References (39)
  • 1
    • 68249159896 scopus 로고    scopus 로고
    • Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
    • Li M, Balch C, Montgomery J, Jeong M, Chung J, Yan P, et al. Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. BMC Medical Genomics 2009; 2:34.
    • (2009) BMC Medical Genomics , vol.2 , pp. 34
    • Li, M.1    Balch, C.2    Montgomery, J.3    Jeong, M.4    Chung, J.5    Yan, P.6
  • 2
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage iii and stage iv ovarian cancer
    • McGuire WP, Hoskins WJ, Brady MF, Kucera PR, Partridge EE, Look KY, et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage iii and stage iv ovarian cancer. N Engl J Med 1996; 334:1-6.
    • (1996) N Engl J Med , vol.334 , pp. 1-6
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3    Kucera, P.R.4    Partridge, E.E.5    Look, K.Y.6
  • 3
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: Strategies for overcoming resistance to chemotherapy
    • Agarwal R, Kaye SB. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 2003; 3:502-516.
    • (2003) Nat Rev Cancer , vol.3 , pp. 502-516
    • Agarwal, R.1    Kaye, S.B.2
  • 4
    • 34249321653 scopus 로고    scopus 로고
    • Mechanisms of resistance to cisplatin and carboplatin
    • Stewart DJ. Mechanisms of resistance to cisplatin and carboplatin. Crit Rev Oncol Hematol 2007; 63:12-31.
    • (2007) Crit Rev Oncol Hematol , vol.63 , pp. 12-31
    • Stewart, D.J.1
  • 5
    • 84855929956 scopus 로고    scopus 로고
    • Using the reconstructed genome-scale human metabolic network to study physiology and pathology
    • Bordbar A, Palsson BO. Using the reconstructed genome-scale human metabolic network to study physiology and pathology. J Intern Med 2012; 271:131-141.
    • (2012) J Intern Med , vol.271 , pp. 131-141
    • Bordbar, A.1    Palsson, B.O.2
  • 6
    • 84898789997 scopus 로고    scopus 로고
    • The effect of exercise training on the level of tissue IL-6 and vascular endothelial growth factor in breast cancer bearing mice
    • Shalamzari SA, Agha-Alinejad H, Alizadeh S, Shahbazi S, Khatib ZK, Kazemi A, et al. The effect of exercise training on the level of tissue IL-6 and vascular endothelial growth factor in breast cancer bearing mice. Iran J Basic Med Sci 2014; 17:231-258.
    • (2014) Iran J Basic Med Sci , vol.17 , pp. 231-258
    • Shalamzari, S.A.1    Agha-Alinejad, H.2    Alizadeh, S.3    Shahbazi, S.4    Khatib, Z.K.5    Kazemi, A.6
  • 7
    • 84857992195 scopus 로고    scopus 로고
    • Targeting cancer metabolism – aiming at a tumour's sweet-spot
    • Jones NP, Schulze A. Targeting cancer metabolism – aiming at a tumour's sweet-spot. Drug Discov Today 2012; 17:232-241.
    • (2012) Drug Discov Today , vol.17 , pp. 232-241
    • Jones, N.P.1    Schulze, A.2
  • 8
    • 75149129569 scopus 로고    scopus 로고
    • A protocol for generating a high-quality genome-scale metabolic reconstruction
    • Thiele I, Palsson BO. A protocol for generating a high-quality genome-scale metabolic reconstruction. Nat Protoc 2010; 5:93-121.
    • (2010) Nat Protoc , vol.5 , pp. 93-121
    • Thiele, I.1    Palsson, B.O.2
  • 9
    • 33846910173 scopus 로고    scopus 로고
    • Global reconstruction of the human metabolic network based on genomic and bibliomic data
    • Duarte NC, Becker SA, Jamshidi N, Thiele I, Mo ML, Vo TD, et al. Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci 2007; 104:1777-1782.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 1777-1782
    • Duarte, N.C.1    Becker, S.A.2    Jamshidi, N.3    Thiele, I.4    Mo, M.L.5    Vo, T.D.6
  • 12
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 2008; 7:11-20.
    • (2008) Cell Metab , vol.7 , pp. 11-20
    • Deberardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 14
    • 9544253891 scopus 로고    scopus 로고
    • Genome-scale models of microbial cells: Evaluating the consequences of constraints
    • Price ND, Reed JL, Palsson BO. Genome-scale models of microbial cells: evaluating the consequences of constraints. Nat Rev Microbiol 2004; 2:886-897.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 886-897
    • Price, N.D.1    Reed, J.L.2    Palsson, B.O.3
  • 15
    • 79953661070 scopus 로고    scopus 로고
    • Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the warburg effect
    • Shlomi T, Benyamini T, Gottlieb E, Sharan R, Ruppin E. Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the warburg effect. PLoS Comput Biol 2011; 7:e1002018.
    • (2011) Plos Comput Biol , vol.7
    • Shlomi, T.1    Benyamini, T.2    Gottlieb, E.3    Sharan, R.4    Ruppin, E.5
  • 16
    • 79953661070 scopus 로고    scopus 로고
    • Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect
    • Shlomi T, Benyamini T, Gottlieb E, Sharan R, Ruppin E. Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect. PLoS Comput Biol. 2011;7:e1002018.
    • (2011) Plos Comput Biol , vol.7
    • Shlomi, T.1    Benyamini, T.2    Gottlieb, E.3    Sharan, R.4    Ruppin, E.5
  • 17
    • 84866487453 scopus 로고    scopus 로고
    • Integration of expression data in genome-scale metabolic network reconstructions
    • Blazier AS, Papin JA. Integration of expression data in genome-scale metabolic network reconstructions. Front Physiol 2012; 3:299.
    • (2012) Front Physiol , vol.3 , pp. 299
    • Blazier, A.S.1    Papin, J.A.2
  • 18
    • 44949225040 scopus 로고    scopus 로고
    • Context-specific metabolic networks are consistent with experiments
    • Becker SA, Palsson BO. Context-specific metabolic networks are consistent with experiments. PLoS Comput Biol 2008; 4:e1000082.
    • (2008) Plos Comput Biol , vol.4
    • Becker, S.A.1    Palsson, B.O.2
  • 19
    • 70049110173 scopus 로고    scopus 로고
    • Interpreting expression data with metabolic flux models: Predicting Mycobacterium tuberculosis mycolic acid production
    • Colijn C, Brandes A, Zucker J, Lun DS, Weiner B, Farhat MR, et al. Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production. PLoS Comput Biol 2009; 5:e1000489.
    • (2009) Plos Comput Biol , vol.5
    • Colijn, C.1    Brandes, A.2    Zucker, J.3    Lun, D.S.4    Weiner, B.5    Farhat, M.R.6
  • 21
    • 66149122278 scopus 로고    scopus 로고
    • Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p
    • Moxley JF, Jewett MC, Antoniewicz MR, Villas-Boas SG, Alper H, Wheeler RT, et al. Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p. Proc Natl Acad Sci USA 2009; 106:6477-6482.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6477-6482
    • Moxley, J.F.1    Jewett, M.C.2    Antoniewicz, M.R.3    Villas-Boas, S.G.4    Alper, H.5    Wheeler, R.T.6
  • 22
    • 79951536020 scopus 로고    scopus 로고
    • Functional integration of a metabolic network model and expression data without arbitrary thresholding
    • Jensen PA, Papin JA. Functional integration of a metabolic network model and expression data without arbitrary thresholding. Bioinformatics 2011; 27:541-547.
    • (2011) Bioinformatics , vol.27 , pp. 541-547
    • Jensen, P.A.1    Papin, J.A.2
  • 23
    • 84866539049 scopus 로고    scopus 로고
    • RELATCH: Relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations
    • Kim J, Reed JL. RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations. Genome Biol 2012; 13:R78.
    • (2012) Genome Biol , vol.13 , pp. R78
    • Kim, J.1    Reed, J.L.2
  • 24
    • 84863662483 scopus 로고    scopus 로고
    • Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT
    • Agren R, Bordel S, Mardinoglu A, Pornputtapong N, Nookaew I, Nielsen J. Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PLoS Comput Biol 2012; 8:e1002518.
    • (2012) Plos Comput Biol , vol.8
    • Agren, R.1    Bordel, S.2    Mardinoglu, A.3    Pornputtapong, N.4    Nookaew, I.5    Nielsen, J.6
  • 25
    • 84870933131 scopus 로고    scopus 로고
    • Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
    • Wang Y, Eddy JA, Price ND. Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE. BMC Syst Biol 2012; 6:153.
    • (2012) BMC Syst Biol , vol.6 , pp. 153
    • Wang, Y.1    Eddy, J.A.2    Price, N.D.3
  • 26
    • 77957556494 scopus 로고    scopus 로고
    • Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines
    • Li L, Zhou X, Ching WK, Wang P. Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines. BMC Bioinformatics 2010; 11:501.
    • (2010) BMC Bioinformatics , vol.11 , pp. 501
    • Li, L.1    Zhou, X.2    Ching, W.K.3    Wang, P.4
  • 27
    • 84867527044 scopus 로고    scopus 로고
    • Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
    • Jerby L, Wolf L, Denkert C, Stein GY, Hilvo M, Oresic M, et al. Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer. Cancer Res 2012; 72:5712-5720.
    • (2012) Cancer Res , vol.72 , pp. 5712-5720
    • Jerby, L.1    Wolf, L.2    Denkert, C.3    Stein, G.Y.4    Hilvo, M.5    Oresic, M.6
  • 28
    • 44949225040 scopus 로고    scopus 로고
    • Context-specific metabolic networks are consistent with experiments
    • Becker SA, Palsson BO. Context-specific metabolic networks are consistent with experiments. PLoS Comput Biol 2008; 4:e1000082.
    • (2008) Plos Comput Biol , vol.4
    • Becker, S.A.1    Palsson, B.O.2
  • 30
    • 79959923767 scopus 로고    scopus 로고
    • Identification of novel therapeutic targets in microdissected clear cell ovarian cancers
    • Stany MP, Vathipadiekal V, Ozbun L, Stone RL, Mok SC, Xue H, et al. Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One 2011; 6:e21121.
    • (2011) Plos One , vol.6
    • Stany, M.P.1    Vathipadiekal, V.2    Ozbun, L.3    Stone, R.L.4    Mok, S.C.5    Xue, H.6
  • 31
    • 79551662521 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: The COBRA Toolbox v2.0
    • Schellenberger J, Que R, Fleming RMT, Thiele I, Orth JD, Feist AM, et al. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat Protoc 2011; 6:1290-1307.
    • (2011) Nat Protoc , vol.6 , pp. 1290-1307
    • Schellenberger, J.1    Que, R.2    Fleming, R.3    Thiele, I.4    Orth, J.D.5    Feist, A.M.6
  • 32
    • 77649187905 scopus 로고    scopus 로고
    • The Warburg effect and mitochondrial stability in cancer cells
    • Gogvadze V, Zhivotovsky B, Orrenius S. The Warburg effect and mitochondrial stability in cancer cells. Mol Aspects Med 2010; 31:60-74.
    • (2010) Mol Aspects Med , vol.31 , pp. 60-74
    • Gogvadze, V.1    Zhivotovsky, B.2    Orrenius, S.3
  • 33
    • 77649183649 scopus 로고    scopus 로고
    • Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
    • Ralph SJ, Rodríguez-Enríquez S, Neuzil J, Moreno-Sánchez R. Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger. Mol Aspects Med 2010; 31:29-59.
    • (2010) Mol Aspects Med , vol.31 , pp. 29-59
    • Ralph, S.J.1    Rodríguez-Enríquez, S.2    Neuzil, J.3    Moreno-Sánchez, R.4
  • 35
    • 0028884492 scopus 로고
    • Methylmalonic Acid Inhibits Respiration in Rat Liver Mitochondria
    • Toyoshima S, Watanabe F, Saido H, Miyatake K, Nakano Y. Methylmalonic Acid Inhibits Respiration in Rat Liver Mitochondria. J Nutr 1995; 125:2846-2850.
    • (1995) J Nutr , vol.125 , pp. 2846-2850
    • Toyoshima, S.1    Watanabe, F.2    Saido, H.3    Miyatake, K.4    Nakano, Y.5
  • 36
    • 14844310360 scopus 로고    scopus 로고
    • Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway
    • Fernandez-Gomez FJ, Galindo MF, Gómez-Lázaro M, Yuste VJ, Comella JX, Aguirre N, et al. Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway. Br J Pharmacol 2005; 144:528-537.
    • (2005) Br J Pharmacol , vol.144 , pp. 528-537
    • Fernandez-Gomez, F.J.1    Galindo, M.F.2    Gómez-Lázaro, M.3    Yuste, V.J.4    Comella, J.X.5    Aguirre, N.6
  • 37
    • 40849097529 scopus 로고    scopus 로고
    • Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake
    • Mirandola SR, Melo DR, Schuck PF, Ferreira GC, Wajner M, Castilho RF. Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake. J Inherit Metab Dis 2008; 31:44-54.
    • (2008) J Inherit Metab Dis , vol.31 , pp. 44-54
    • Mirandola, S.R.1    Melo, D.R.2    Schuck, P.F.3    Ferreira, G.C.4    Wajner, M.5    Castilho, R.F.6
  • 38
    • 0021129895 scopus 로고
    • Effects of short and medium chain length fatty acids on pyruvate oxidation by cultured human fibroblasts and rat liver mitochondria
    • Koga Y, Yoshino M, Yamashita F. Effects of short and medium chain length fatty acids on pyruvate oxidation by cultured human fibroblasts and rat liver mitochondria. J Inherit Metab Dis 1984; 7:141-142.
    • (1984) J Inherit Metab Dis , vol.7 , pp. 141-142
    • Koga, Y.1    Yoshino, M.2    Yamashita, F.3
  • 39
    • 65549123260 scopus 로고    scopus 로고
    • Mitochondrial uncoupling and the Warburg effect: Molecular basis for the reprogramming of cancer cell metabolism
    • Samudio I, Fiegl M, Andreeff M. Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism. Cancer Res 2009; 69:2163-2166.
    • (2009) Cancer Res , vol.69 , pp. 2163-2166
    • Samudio, I.1    Fiegl, M.2    Reeff, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.