Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult

Gene

Volumn 562, Issue 1, 2015, Pages 70-75

  Tang, Ming Yi Richard ^a,b   Guo, Huifang ^a,b   Nguyen, Thi Thuy Trang ^a,b   Low, Liy Sim ^a,b,f   Jackson, Rebecca A ^a   Yamada, Takatomi ^e   Chen, Ee Sin ^a,b,c,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e CHUO UNIVERSITY   (Japan)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Doxorubicin; Drug resistance; Fission yeast; Hap2; High mobility group; Nht1; Rhp54; S. pombe

Indexed keywords

DOUBLE STRANDED DNA; DOXORUBICIN; FUNGAL DNA; FUNGAL PROTEIN; HAP2 PROTEIN; HIGH MOBILITY GROUP B PROTEIN; HISTONE ACETYLTRANSFERASE; NHT1 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; DNA HELICASE; RAD54 PROTEIN, S POMBE; SCHIZOSACCHAROMYCES POMBE PROTEIN;

ANTIFUNGAL RESISTANCE; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CELL VIABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DELETION MUTANT; DNA ADDUCT; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FUNGAL CELL CULTURE; FUNGAL GENOME; GENE CASSETTE; GENE CONTROL; GENE DELETION; GENE DISRUPTION; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENOMICS; HOMOLOGOUS RECOMBINATION; MOLECULAR INTERACTION; MOLECULAR PHYLOGENY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SCHIZOSACCHAROMYCES POMBE; TRANSCRIPTION REGULATION; DNA DAMAGE; DRUG EFFECTS; EPISTASIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RECOMBINATION REPAIR; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

ANTIBIOTICS, ANTINEOPLASTIC; DNA DAMAGE; DNA HELICASES; DOXORUBICIN; DRUG RESISTANCE, FUNGAL; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION, FUNGAL; HMGB PROTEINS; RECOMBINATIONAL DNA REPAIR; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EID: 84925057219     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2015.02.041     Document Type: Article

References (37)

1. + gene in DNA double-stranded break repair in association with the Mre11-Rad50-Nbs1 complex. Mol. Cell. Biol. 2008, 28:3639-3651.
2. Aligianni S., Lackner D.H., Klier S., Rustici G., Wilhelm B.T., Marguerat S., Codlin S., Brama A., de Bruin R.A., Bähler J. The fission yeast homeodomain protein Yox1 binds to MBF and confines MBF-dependent cell cycle transcription to G1-S via negative feedback. PLoS Genet. 2009, 5:e1000626.
3. Bao Y., Shen X. Chromatin remodeling in DNA double-stranded break repair. Curr. Opin. Genet. Dev. 2007, 17:126-131.
4. Basili S., Moro S. Novel camptothecin derivatives as topoisomerase I inhibitors. Expert Opin. Ther. Pat. 2009, 19:555-574.
5. Bugreev D.V., Rossi M.J., Mazin A.V. Cooperation of RAD51 and RAD54 in regression of a model replication fork. Nucleic Acids Res. 2010, 39:2153-2164.
6. Capranico G., De Isabella P., Penco S., Tinelli S., Zunino F. Role of DNA breakage in cytotoxicity of doxorubicin,9-deoxydoxorubicin, and 4-demthyl-6-deoxydoxorubicin in mature leukemia P388 cells. Cancer Res. 1989, 49:2022-2027.
7. Carvalho C., Santos R.X., Cardoso S., Correia S., Oliveira P.J., Santos M.S., Moreira P.I. Doxorubicin: the good, the bad and the ugly effect. Curr. Med. Chem. 2009, 16:3267-3285.
8. Cavero S., Limbo O., Russell P. Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast. PLoS Genet. 2010, 6:e1001138.
9. Chen E.S., Saitoh S., Yanagida M., Takahashi K. A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast. Mol. Cell 2003, 11:175-187.
10. Dawson K., Toone W.M., Jones N., Wilkinson E.R. Loss of vacuolar ATPase function and ceramide synthesis results in multidrug sensitivity in Schizosaccharomyces pombe. Eukaryot Cell 2008, 7:926-937.
11. Dixon S.J., Costanzo M., Baryshnikova A., Andrews B., Boone C. Systematic mapping of genetic interaction networks. Annu. Rev. Genet. 2009, 43:601-625.
12. Ferreira M.E., Berndt K.D., Nilsson J., Wright A.P. WD40 domain divergence is important for functional differences between the fission yeast Tup11 and Tup12 co-repressor proteins. PLoS ONE 2010, 5:e11009.
13. Hayashi T., Fujita Y., Iwasaki O., Adachi Y., Takahashi K., Yanagida M. Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell 2004, 118:715-729.
14. Helmlinger D., Marguerat S., Villén J., Gygi S.P., Bähler J., Winston F. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Genes Dev. 2008, 22:3184-3195.
15. Hogan C.J., Aligianni S., Durand-Dubief M., Persson J., Will W.R., Webster J., Wheeler L., Mattews C.K., Elderkin S., Oxley D., Ekwall K., Varga-Weisz P.D. Fission yeast Iec1-Ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism. Mol. Cell. Biol. 2010, 30:657-674.
16. Huang J., Ni J., Liu K., Yu Y., Kang R., Vernon P., Cao L., Tang D. HMGB1 promotes drug resistance in osteosarcoma. Cancer Res. 2012, 72:230-238.
17. Khasanov F.K., Savchenko G.V., Bashkirov E.V., Korolev V.G., Heyer W.D., Bashkirov V.I. A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli Rec A. Genetics 1999, 152:1557-1572.
18. Kujjo L.L., Laine T., Pereira R.J., Kagawa W., Kurumizawa H., Yokoyama S., Perez G.I. Enhancing survival of mouse oocyte following chemotherapy or aging by targeting Bax and Rad51. PLoS ONE 2010, 5:e9204.
19. Liu X., McLeod I., Anderson S., Yates J.R., He X. Molecular analysis of kinetochore architecture in fission yeast. EMBO J. 2005, 24:2919-2930.
20. Monahan B.J., Villén J., Margueret S., Bähler J., Gygi S.P., Winston F. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Nat. Struct. Mol. Biol. 2008, 15:873-880.
21. Morrison A.J., Highland J., Krogan N.J., Arbel-Eden A., Greenblatt J.F., Haber J.E., Shen X. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodelling to DNA damage repair. Cell 2004, 119:767-775.
22. Nguyen T.T.T., Lim J.S.L., Tang R.M.Y., Zhang L., Chen E.S. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Sci. Rep. 2015, 5:8400.
23. Nicolas E., Yamada T., Cam H.P., Fitzgerald R.C., Kobayashi R., Grewal S.I. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nat. Struct. Mol. Biol. 2007, 14:372-380.
24. Pommier Y., Leo E., Zhang H., Marchand C. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem. Biol. 2010, 17:421-433.
25. Reeves R. Nuclear functions of the HMG proteins. Biochim. Biophys. Acta 2010, 1799:3-14.
26. Schulze J.M., Wang A.Y., Kobor M.S. Reading chromatin: insights from yeast into YEATS domain structure and function. Epigenetics 2010, 5:573-577.
27. Spencer D.M., Bilardi R.A., Koch T.H., Post G.C., Nafie J.W., Kimura K., Cutts S.M., Phillips D.R. DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair. Mutat. Res. 2008, 638:110-121.
28. Tacar O., Sriamornsak P., Dass C.R. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J. Pharm. Pharmacol. 2013, 65:157-170.
29. Takahashi K., Chen E.S., Yanagida M. Requirement of Mis6 centromeric connector for localizing a CENP-A-like protein in fission yeast. Science 2000, 288:2215-2219.
30. Tay Z., Eng R.J., Sajiki K., Lim K.K., Tang M.Y., Yanagida M., Chen E.S. Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast. PLoS ONE 2013, 8:e55041.
31. Tay Z., Koo S.H., Nguyen T.T., Tan T.S., Chen M.L., Chin C.F., Lim K.K., Ang W.H., Bay B.H., Lee E.J., Chen E.S. P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells. Curr. Med. Chem. 2014, 21:251-260.
32. Thornton G., Wilkinson C.R., Toone W.M., Jones N. A novel pathway determining multidrug sensitivity in Schizosaccharomyces pombe. Genes Cells 2005, 10:941-951.
33. Verma R., Rigatti M.J., Belinsky G.S., Godman C.A., Giardina C. DNA damage response to the Mdm2 inhibitor Nutlin-3. Biochem. Pharmacol. 2010, 79:565-574.
34. Wang J.C. Cellular roles of DNA topoisomerases: a molecular perspective. Nat. Rev. Mol. Cell Biol. 2002, 3:430-440.
35. Wyatt M.D., Pittman D.L. Methylating agents and DNA repair response: methylated bases and sources of strand breaks. Chem. Res. Toxicol. 2006, 19:1580-1594.
36. Young J.A., Schreckhise R.W., Steiner W.W., Smith G.R. Meiotic recombination remote from prominent DNA break sites in S. pombe. Mol. Cell 2002, 9:253-263.
37. Yu Y., Ren J.Y., Zhang J.M., Suo F., Fang X.F., Wu F., Du L.L. A proteome-wide visual wide screen identifies fission yeast proteins localizing to DNA double-stranded breaks. DNA Repair 2013, 12:433-443.