Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes

International Journal of Pharmaceutics

Volumn 460, Issue 1-2, 2014, Pages 280-288

  Shen, Li Na ^a   Zhang, Yong Tai ^a   Wang, Qin ^a   Xu, Ling ^a   Feng, Nian Ping ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Cyclooxygenase 2; Inflammation; Liposome; Permeability; Transdermal

Indexed keywords

APIGENIN; CYCLOOXYGENASE 2; DRUG CARRIER; ETHOSOME; LIPOSOME; MACROGOL 400; PHOSPHOLIPID; PROPYLENE GLYCOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMATITIS; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; ENCAPSULATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; ULTRAVIOLET B RADIATION; ZETA POTENTIAL;

COX-2; CYCLOOXYGENASE-2; DEFORMABLE LIPOSOME GROUP; DEFORMABLE LIPOSOMES; DLS; DLSG; EE; EMPTY ETHOSOMES WITH EXTERNAL APIGENIN; ENTRAPMENT EFFICIENCY; ES; ES-OUT; ES-OUT GROUP; ES-OUTG; ETHOSOMES; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; INFLAMMATION; LIPOSOME; LIPOSOME GROUP; LIPOSOMES; LS; LSG; MCG; MODEL CONTROL GROUP; NCG; NORMAL CONTROL GROUP; PARTICLE-SIZE CHANGE RATE; PC; PEG400; PERMEABILITY; PHOSPHOLIPID; POLYETHYLENE GLYCOL 400; SCR; TRANSDERMAL; ULTRAVIOLET; ULTRAVIOLET B; UV; UVB;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; APIGENIN; CYCLOOXYGENASE 2; DERMATITIS; DRUG DELIVERY SYSTEMS; ETHANOL; LIPOSOMES; MALE; MICE; PROPYLENE GLYCOL; RATS; RATS, SPRAGUE-DAWLEY; SKIN; ULTRAVIOLET RAYS;

EID: 84892444449     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.11.017     Document Type: Article

References (26)

1. A.O. Abu-Yousif, K.A. Smith, S. Getsios, K.J. Green, R.T. Van Dross, and J.C. Pelling Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures Cancer Res. 68 2008 3057 3065 (Pubitemid 351556308)
2. D. Ainbinder, D. Paolino, M. Fresta, and E. Touitou Drug delivery applications with ethosomes J. Biomed. Nanotechnol. 6 2010 558 568
3. L. Al Shaal, R. Shegokar, and R.H. Müller Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation Int. J. Pharm. 420 2011 133 140
4. N. Begum, and N.R. Prasad Apigenin, a dietary antioxidant, modulates gamma radiation-induced oxidative damages in human peripheral blood lymphocytes Biomed. Prev. Nutr. 2 2012 16 24
5. S. Byun, J. Park, E. Lee, S. Lim, J.G. Yu, S.J. Lee, H. Chen, Z. Dong, K.W. Lee, and H.J. Lee Src kinase is a direct target of apigenin against UVB-induced skin inflammation Carcinogenesis 34 2012 397 405
6. N. Dayan, and E. Touitou Carriers for skin delivery of trihexyphenidyl HCl: ethosomes vs. liposomes Biomaterials 21 2000 1879 1885 (Pubitemid 30398506)
7. C.M. Duarte, M.R. Quirino, M.C. Patrocínio, and A.L. Anbinder Effects of Chamomillarecutita (L.) on oral wound healing in rats Med. Oral Patol. Oral Cir. Bucal. 16 2011 716 721
8. G.M. El Maghraby, A.C. Williams, and B.W. Barry Skin delivery of oestradiol from lipid vesicles: importance of liposome structure Int. J. Pharm. 204 2000 159 169
9. M.M. Elsayed, O.Y. Abdallah, V.F. Naggar, and N.M. Khalafallah Deformable liposomes and ethosomes: mechanism of enhanced skin delivery Int. J. Pharm. 322 2006 60 66 (Pubitemid 44348860)
10. M.M. Elsayed, O.Y. Abdallah, V.F. Naggar, and N.M. Khalafallah PG-liposomes: novel lipid vesicles for skin delivery of drugs J. Pharm. Pharmacol. 59 2007 1447 1450 (Pubitemid 47606462)
11. Y.P. Fang, Y.H. Tsai, P.C. Wu, and Y.B. Huang Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapy Int. J. Pharm. 356 2008 144 152
12. S. Jain, A.K. Tiwary, B. Sapra, and N.K. Jain Formulation and evaluation of ethosomes for transdermal delivery of lamivudine AAPS PharmSciTech 8 2007 249 257
13. R. Kohen, and A. Nyska Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification Toxicol. Pathol. 30 2002 620 650 (Pubitemid 36018731)
14. G. Li, Y. Fan, C. Fan, X. Li, X. Wang, M. Li, and Y. Liu Tacrolimus-loaded ethosomes: physicochemical characterization and in vivo evaluation Eur. J. Pharm. Biopharm. 82 2012 49 57
15. M. Manconi, S. Mura, C. Sinico, A.M. Fadda, A.O. Vila, and F. Molina Development and characterization of liposomes containing glycols as carriers for diclofenac Colloids Surf. A. 342 2009 53 58
16. H. Masaki Role of antioxidants in the skin: anti-aging effects J. Dermatol. Sci. 58 2010 85 90
17. Y. Matsumura, and H.N. Ananthaswamy Toxic effects of ultraviolet radiation on the skin Toxicol. Appl. Pharmacol. 195 2004 298 308 (Pubitemid 38338650)
18. D. Patel, S. Shukla, and S. Gupta Apigenin and cancer chemoprevention: progress, potential and promise Int. J. Oncol. 30 2007 233 245 (review)
19. M. Portugal, V. Barak, I. Ginsburg, and R. Kohen Interplay among oxidants, antioxidants, and cytokines in skin disorders: present status and future considerations Biomed. Pharmacother. 61 2007 412 422 (Pubitemid 47239346)
20. Y. Rao, F. Zheng, X. Zhang, J. Gao, and W. Liang In vitro percutaneous permeation and skin accumulation of finasteride using vesicular ethosomal carriers AAPS PharmSciTech 9 2008 860 865
21. K.N. Rithidech, M. Tungjai, P. Reungpatthanaphong, L. Honikel, and S.R. Simon Attenuation of oxidative damage and inflammatory responses by apigenin given to mice after irradiation Mutat. Res. 749 2012 29 38
22. X. Tong, R.T. VanDross, A. Abu-Yousif, A.R. Morrison, and J.C. Pelling Apigenin prevents UVB-induced cyclooxygenase 2 expression: coupled mRNA stabilization and translational inhibition Mol. Cell. Biol. 27 2007 283 296 (Pubitemid 46013251)
23. E. Touitou, N. Dayan, L. Bergelson, B. Godin, and M. Eliaz Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties J. Control. Release 65 2000 403 418 (Pubitemid 30122942)
24. Y. Wo, Z. Zhang, Y. Zhang, D. Wang, Z. Pu, W. Su, Y. Qian, Y. Li, and D. Cui Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar J. Nanosci. Nanotechnol. 11 2011 7840 7847
25. J.P. Zhang, Y.H. Wei, Y. Zhou, Y.Q. Li, and X.A. Wu Ethosomes, binary ethosomes and transfersomes of terbinafine hydrochloride: a comparative study Arch. Pharm. Res. 35 2012 109 117
26. Y. Zhou, Y. Wei, H. Liu, G. Zhang, and X. Wu Preparation and in vitro evaluation of ethosomal total alkaloids of Sophora alopecuroides loaded by a transmembrane pH-gradient method AAPS PharmSciTech 11 2010 1350 1358