메뉴 건너뛰기




Volumn 63, Issue 10, 2015, Pages 2734-2740

Signaling pathway involved in the immunomodulatory effect of ganoderma atrum polysaccharide in spleen lymphocytes

Author keywords

Ganoderma atrum polysaccharide; immunomodulatory effect; interleukin 2; signaling pathway; spleen lymphocytes

Indexed keywords

CALCIUM; CHEMICAL ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; LYMPHOCYTES;

EID: 84925012815     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b00028     Document Type: Article
Times cited : (62)

References (35)
  • 2
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham, D. E. Calcium signaling Cell 2007, 131, 1047-1058
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 3
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • Feske, S. Calcium signalling in lymphocyte activation and disease Nat. Rev. Immunol. 2007, 7, 690-702
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 690-702
    • Feske, S.1
  • 4
    • 0033779701 scopus 로고    scopus 로고
    • Calcineurin: Form and function
    • Rusnak, F.; Mertz, P. Calcineurin: Form and function Physiol. Rev. 2000, 80, 1483-1521
    • (2000) Physiol. Rev. , vol.80 , pp. 1483-1521
    • Rusnak, F.1    Mertz, P.2
  • 5
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A.; Luo, C.; Hogan, P. G. Transcription factors of the NFAT family: Regulation and function Annu. Rev. Immunol. 1997, 15, 707-747
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 6
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • Hogan, P. G.; Chen, L.; Nardone, J.; Rao, A. Transcriptional regulation by calcium, calcineurin, and NFAT Genes Dev. 2003, 17, 2205-2232
    • (2003) Genes Dev. , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 7
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka, Y. Studies and perspectives of protein kinase C Science 1986, 233, 305-312
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 8
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton, A. C. Protein kinase C: Structure, function, and regulation J. Biol. Chem. 1995, 270, 28495-28498
    • (1995) J. Biol. Chem. , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 12
    • 84884806956 scopus 로고    scopus 로고
    • Effect of selenium-enriched exopolysaccharide produced by Lactococcus lactis subsp. Lactis on signaling molecules in mouse spleen lymphocytes
    • Liu, L.; Pan, D.; Zeng, X.; Li, H. Effect of selenium-enriched exopolysaccharide produced by Lactococcus lactis subsp. lactis on signaling molecules in mouse spleen lymphocytes Food Funct. 2013, 4, 1489-1495
    • (2013) Food Funct. , vol.4 , pp. 1489-1495
    • Liu, L.1    Pan, D.2    Zeng, X.3    Li, H.4
  • 13
    • 77949904217 scopus 로고    scopus 로고
    • Immunopotentiation on murine spleen lymphocytes induced by polysaccharide fraction of Panax ginseng via upregulating calcineurin activity
    • Zhang, S. D.; Yin, Y. X.; Wei, Q. Immunopotentiation on murine spleen lymphocytes induced by polysaccharide fraction of Panax ginseng via upregulating calcineurin activity APMIS 2010, 118, 288-296
    • (2010) APMIS , vol.118 , pp. 288-296
    • Zhang, S.D.1    Yin, Y.X.2    Wei, Q.3
  • 14
    • 17044367362 scopus 로고    scopus 로고
    • Antimicrobial activity of the medicinal mushroom Ganoderma
    • Gao, Y.; Tang, W.; Gao, H.; Chan, E.; Lan, J.; Li, X.; Zhou, S. Antimicrobial activity of the medicinal mushroom Ganoderma Food Rev. Int. 2005, 21, 211-229
    • (2005) Food Rev. Int. , vol.21 , pp. 211-229
    • Gao, Y.1    Tang, W.2    Gao, H.3    Chan, E.4    Lan, J.5    Li, X.6    Zhou, S.7
  • 15
    • 84882244013 scopus 로고    scopus 로고
    • Current development of polysaccharides from Ganoderma: Isolation, structure and bioactivities
    • Nie, S. P.; Zhang, H.; Li, W. J.; Xie, M. Y. Current development of polysaccharides from Ganoderma: Isolation, structure and bioactivities Bioact. Carbohydr. Diet. Fibre 2013, 1, 10-20
    • (2013) Bioact. Carbohydr. Diet. Fibre , vol.1 , pp. 10-20
    • Nie, S.P.1    Zhang, H.2    Li, W.J.3    Xie, M.Y.4
  • 16
    • 35449005201 scopus 로고    scopus 로고
    • Purification, composition analysis and antioxidant activity of a polysaccharide from the fruiting bodies of Ganoderma atrum
    • Chen, Y.; Xie, M. Y.; Nie, S. P.; Li, C.; Wang, Y. X. Purification, composition analysis and antioxidant activity of a polysaccharide from the fruiting bodies of Ganoderma atrum Food Chem. 2008, 107, 231-241
    • (2008) Food Chem. , vol.107 , pp. 231-241
    • Chen, Y.1    Xie, M.Y.2    Nie, S.P.3    Li, C.4    Wang, Y.X.5
  • 17
    • 84862798063 scopus 로고    scopus 로고
    • Structural characterisation of a novel bioactive polysaccharide from Ganoderma atrum
    • Zhang, H.; Li, W. J.; Nie, S. P.; Chen, Y.; Wang, Y. X.; Xie, M. Y. Structural characterisation of a novel bioactive polysaccharide from Ganoderma atrum Carbohydr. Polym. 2012, 88, 1047-1054
    • (2012) Carbohydr. Polym. , vol.88 , pp. 1047-1054
    • Zhang, H.1    Li, W.J.2    Nie, S.P.3    Chen, Y.4    Wang, Y.X.5    Xie, M.Y.6
  • 18
    • 79955015056 scopus 로고    scopus 로고
    • Enhancement of cyclophosphamide-induced antitumor effect by a novel polysaccharide from Ganoderma atrum in sarcoma 180-bearing mice
    • Li, W. J.; Nie, S. P.; Chen, Y.; Wang, Y. X.; Li, C.; Xie, M. Y. Enhancement of cyclophosphamide-induced antitumor effect by a novel polysaccharide from Ganoderma atrum in sarcoma 180-bearing mice J. Agric. Food Chem. 2011, 59, 3707-3716
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 3707-3716
    • Li, W.J.1    Nie, S.P.2    Chen, Y.3    Wang, Y.X.4    Li, C.5    Xie, M.Y.6
  • 19
    • 79951802301 scopus 로고    scopus 로고
    • Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response
    • Li, W. J.; Chen, Y.; Nie, S. P.; Xie, M. Y.; He, M.; Zhang, S. S.; Zhu, K. X. Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response J. Cell Biochem. 2011, 112, 860-871
    • (2011) J. Cell Biochem. , vol.112 , pp. 860-871
    • Li, W.J.1    Chen, Y.2    Nie, S.P.3    Xie, M.Y.4    He, M.5    Zhang, S.S.6    Zhu, K.X.7
  • 21
    • 84876487580 scopus 로고    scopus 로고
    • Polysaccharide from Ganoderma atrum evokes antitumor activity via toll-like receptor 4-mediated NF-B and mitogen-activated protein kinase signaling pathways
    • Zhang, S. S.; Nie, S. P.; Huang, D. F.; Huang, J. Q.; Wang, Y. X.; Xie, M. Y. Polysaccharide from Ganoderma atrum evokes antitumor activity via toll-like receptor 4-mediated NF-B and mitogen-activated protein kinase signaling pathways J. Agric. Food Chem. 2013, 61, 3676-3682
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 3676-3682
    • Zhang, S.S.1    Nie, S.P.2    Huang, D.F.3    Huang, J.Q.4    Wang, Y.X.5    Xie, M.Y.6
  • 22
    • 84873411346 scopus 로고    scopus 로고
    • Macrophage immunomodulatory activity of a purified polysaccharide isolated from Ganoderma atrum
    • Yu, Q.; Nie, S. P.; Li, W. J.; Zheng, W. Y.; Yin, P. F.; Gong, D. M.; Xie, M. Y. Macrophage immunomodulatory activity of a purified polysaccharide isolated from Ganoderma atrum Phytother. Res. 2013, 27, 186-191
    • (2013) Phytother. Res. , vol.27 , pp. 186-191
    • Yu, Q.1    Nie, S.P.2    Li, W.J.3    Zheng, W.Y.4    Yin, P.F.5    Gong, D.M.6    Xie, M.Y.7
  • 23
    • 84893472487 scopus 로고    scopus 로고
    • Toll-like receptor 4-mediated ROS signaling pathway involved in Ganoderma atrum polysaccharide-induced tumor necrosis factor- secretion during macrophage activation
    • Yu, Q.; Nie, S. P.; Wang, J. Q.; Yin, P. F.; Huang, D. F.; Li, W. J.; Xie, M. Y. Toll-like receptor 4-mediated ROS signaling pathway involved in Ganoderma atrum polysaccharide-induced tumor necrosis factor- secretion during macrophage activation Food Chem. Toxicol. 2014, 66, 14-22
    • (2014) Food Chem. Toxicol. , vol.66 , pp. 14-22
    • Yu, Q.1    Nie, S.P.2    Wang, J.Q.3    Yin, P.F.4    Huang, D.F.5    Li, W.J.6    Xie, M.Y.7
  • 24
    • 84866889182 scopus 로고    scopus 로고
    • Polysaccharide from Ganoderma atrum induces tumor necrosis factor- secretion via phosphoinositide 3-kinase/Akt, mitogen-activated protein kinase and nuclear factor-B signaling pathways in RAW264.7 cells
    • Yu, Q.; Nie, S. P.; Wang, J. Q.; Yin, P. F.; Li, W. J.; Xie, M. Y. Polysaccharide from Ganoderma atrum induces tumor necrosis factor- secretion via phosphoinositide 3-kinase/Akt, mitogen-activated protein kinase and nuclear factor-B signaling pathways in RAW264.7 cells Int. Immunopharmacol. 2012, 14, 362-368
    • (2012) Int. Immunopharmacol. , vol.14 , pp. 362-368
    • Yu, Q.1    Nie, S.P.2    Wang, J.Q.3    Yin, P.F.4    Li, W.J.5    Xie, M.Y.6
  • 25
    • 70349730219 scopus 로고    scopus 로고
    • The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes
    • Li, W. J.; Nie, S. P.; Yan, Y.; Zhu, S. B.; Xie, M. Y. The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes Life Sci. 2009, 85, 634-641
    • (2009) Life Sci. , vol.85 , pp. 634-641
    • Li, W.J.1    Nie, S.P.2    Yan, Y.3    Zhu, S.B.4    Xie, M.Y.5
  • 27
    • 84875799006 scopus 로고    scopus 로고
    • A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia
    • Zhu, K. X.; Nie, S. P.; Li, C.; Lin, S. L.; Xing, M. M.; Li, W. J.; Gong, D. M.; Xie, M. Y. A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia Int. J. Biol. Macromol. 2013, 57, 142-150
    • (2013) Int. J. Biol. Macromol. , vol.57 , pp. 142-150
    • Zhu, K.X.1    Nie, S.P.2    Li, C.3    Lin, S.L.4    Xing, M.M.5    Li, W.J.6    Gong, D.M.7    Xie, M.Y.8
  • 28
    • 0029025964 scopus 로고
    • The architecture of the interleukin-2 promoter: A reflection of T lymphocyte activation
    • Serfling, E.; Avots, A.; Neumann, M. The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation Biochim. Biophys. Acta, Gene Struct. Expression 1995, 1263, 181-200
    • (1995) Biochim. Biophys. Acta, Gene Struct. Expression , vol.1263 , pp. 181-200
    • Serfling, E.1    Avots, A.2    Neumann, M.3
  • 29
    • 45449093954 scopus 로고    scopus 로고
    • Calcium signaling in lymphocytes
    • Oh-hora, M.; Rao, A. Calcium signaling in lymphocytes Curr. Opin. Immunol. 2008, 20, 250-258
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 250-258
    • Oh-Hora, M.1    Rao, A.2
  • 30
    • 0001018554 scopus 로고
    • Calcineurin: A calcium-and calmodulin-binding protein of the nervous system
    • Klee, C.; Crouch, T.; Krinks, M. Calcineurin: A calcium-and calmodulin-binding protein of the nervous system Proc. Natl. Acad. Sci. U. S. A. 1979, 76, 6270-6273
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 6270-6273
    • Klee, C.1    Crouch, T.2    Krinks, M.3
  • 32
    • 20644466433 scopus 로고    scopus 로고
    • NFAT proteins: Key regulators of T-cell development and function
    • Macian, F. NFAT proteins: Key regulators of T-cell development and function Nat. Rev. Immunol. 2005, 5, 472-484
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 472-484
    • Macian, F.1
  • 33
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • Crabtree, G. R.; Olson, E. N. NFAT signaling: Choreographing the social lives of cells Cell 2002, 109, S67-S79
    • (2002) Cell , vol.109 , pp. 67-S79
    • Crabtree, G.R.1    Olson, E.N.2
  • 34
    • 0035951849 scopus 로고    scopus 로고
    • Calcium, calcineurin, and the control of transcription
    • Crabtree, G. R. Calcium, calcineurin, and the control of transcription J. Biol. Chem. 2001, 276, 2313-2316
    • (2001) J. Biol. Chem. , vol.276 , pp. 2313-2316
    • Crabtree, G.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.