Vif determines the requirement for CBF-β in APOBEC3 degradation

Journal of General Virology

Volumn 96, Issue 4, 2015, Pages 887-892

  Yoshikawa, Rokusuke ^a   Takeuchi, Junko S ^a   Yamada, Eri ^a   Nakano, Yusuke ^a,b   Ren, Fengrong ^c   Tanaka, Hiroshi ^c   Münk, Carsten ^d   Harris, Reuben S ^e   Miyazawa, Takayuki ^a   Koyanag, Yoshio ^a   Sato, Kei ^a,f  

^a KYOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3F; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3Z2A; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3Z2B; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3Z2C; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3Z2Z3; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3Z3; CORE BINDING FACTOR BETA; DNA POLYMERASE; HYDROLASE; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; VIF PROTEIN; APOBEC3 PROTEIN, HUMAN; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE;

ARTICLE; BINDING SITE; DNA LIBRARY; DNA SEQUENCE; DOMESTIC CAT; ENZYME DEGRADATION; FELINE IMMUNODEFICIENCY VIRUS; GENETIC TRANSFECTION; NONHUMAN; OPEN READING FRAME; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PURIFYING SELECTION; VIRUS STRAIN; ANIMAL; CAT; CELL LINE; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; PHYLOGENY;

FELIDAE; FELINE IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; PRIMATES;

ANIMALS; CATS; CELL LINE; CORE BINDING FACTOR BETA SUBUNIT; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; HEK293 CELLS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; PHYLOGENY; VIF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84925004145     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/jgv.0.000027     Document Type: Article

References (39)

1. Adya, N., Castilla, L. H. & Liu, P. P. (2000). Function of CBFb/Bro proteins. Semin Cell Dev Biol 11, 361-368.
2. Ai, Y., Zhu, D., Wang, C., Su, C., Ma, J., Ma, J. & Wang, X. (2014). Corebinding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation. J Virol 88, 12112-12122.
3. Albin, J. S. & Harris, R. S. (2010). Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Expert Rev Mol Med 12, e4.
4. Bravo, J., Li, Z., Speck, N. A. & Warren, A. J. (2001). The leukemiaassociated AML1 (Runx1)-CBF b complex functions as a DNAinduced molecular clamp. Nat Struct Biol 8, 371-378.
5. de Bruijn, M. F. & Speck, N. A. (2004). Core-binding factors in hematopoiesis and immune function. Oncogene 23, 4238-4248.
6. Desimmie, B. A., Delviks-Frankenberrry, K. A., Burdick, R. C., Qi, D., Izumi, T. & Pathak, V. K. (2014). Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all. J Mol Biol 426, 1220-1245.
7. Du, J., Zhao, K., Rui, Y., Li, P., Zhou, X., Zhang, W. & Yu, X. F. (2013). Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta. J Virol 87, 1906-1911.
8. Feng, Y., Baig, T. T., Love, R. P. & Chelico, L. (2014). Suppression of APOBEC3-mediated restriction of HIV-1 by Vif. FrontMicrobiol 5, 450.
9. Gifford, R. J. (2012). Viral evolution in deep time: lentiviruses and mammals. Trends Genet 28, 89-100.
10. Guindon, S., Dufayard, J. F., Lefort, V., Anisimova, M., Hordijk, W. & Gascuel, O. (2010). New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 59, 307-321.
11. Guo, Y., Dong, L., Qiu, X., Wang, Y., Zhang, B., Liu, H., Yu, Y., Zang, Y., Yang, M. & Huang, Z. (2014). Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif. Nature 505, 229-233.
12. Han, X., Liang, W., Hua, D., Zhou, X., Du, J., Evans, S. L., Gao, Q., Wang, H., Viqueira, R. & other authors (2014). Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase. J Virol 88, 3320-3328.
13. Harris, R. S., Bishop, K. N., Sheehy, A. M., Craig, H. M., Petersen-Mahrt, S. K., Watt, I. N., Neuberger, M. S. & Malim, M. H. (2003). DNA deamination mediates innate immunity to retroviral infection. Cell 113, 803-809.
14. Hultquist, J. F., Binka, M., LaRue, R. S., Simon, V. & Harris, R. S. (2012a). Vif proteins of human and simian immunodeficiency viruses require cellular CBFb to degrade APOBEC3 restriction factors. J Virol 86, 2874-2877.
15. Hultquist, J. F., McDougle, R. M., Anderson, B. D. & Harris, R. S. (2012b). HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor b on genetically distinct surfaces. AIDS Res Hum Retroviruses 28, 1543-1551.
16. Ito, Y. (2008). RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes. Adv Cancer Res 99, 33-76.
17. Jäger, S., Kim, D. Y., Hultquist, J. F., Shindo, K., LaRue, R. S., Kwon, E., Li, M., Anderson, B. D., Yen, L. & other authors (2012). Vif hijacks CBF-b to degrade APOBEC3G and promote HIV-1 infection. Nature 481, 371-375.
18. Kim, D. Y., Kwon, E., Hartley, P. D., Crosby, D. C., Mann, S., Krogan, N. J. & Gross, J. D. (2013). CBFb stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell 49, 632-644.
19. Kitamura, S., Ode, H. & Iwatani, Y. (2011). Structural features of antiviral APOBEC3 proteins are linked to their functional activities. Front Microbiol 2, 258.
20. Kobayashi, T., Koizumi, Y., Takeuchi, J. S., Misawa, N., Kimura, Y., Morita, S., Aihara, K., Koyanagi, Y., Iwami, S. & Sato, K. (2014a). Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation. J Virol 88, 5881-5887.
21. Kobayashi, T., Takeuchi, J. S., Ren, F., Matsuda, K., Sato, K., Kimura, Y., Misawa, N., Yoshikawa, R., Nakano, Y. & other authors (2014b). Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses. Sci Rep 4, 5529.
22. LaRue, R. S., Lengyel, J., Jó nsson, S. R., Andrésdóttir, V. & Harris, R. S. (2010). Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity. J Virol 84, 8193-8201.
23. Mariani, R., Chen, D., Schröfelbauer, B., Navarro, F., König, R., Bollman, B., Münk, C., Nymark-McMahon, H. & Landau, N. R. (2003). Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell 114, 21-31.
24. Münk, C., Beck, T., Zielonka, J., Hotz-Wagenblatt, A., Chareza, S., Battenberg, M., Thielebein, J., Cichutek, K., Bravo, I. G. & other authors (2008). Functions, structure, and read-through alternative splicing of feline APOBEC3 genes. Genome Biol 9, R48.
25. Münk, C., Willemsen, A. & Bravo, I. G. (2012). An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals. BMC Evol Biol 12, 71.
26. Penn, O., Privman, E., Ashkenazy, H., Landan, G., Graur, D. & Pupko, T. (2010). GUIDANCE: a web server for assessing alignment confidence scores. Nucleic Acids Res 38 (Web Server issue), W23-W28.
27. Pond, S. L. & Frost, S. D. (2005). Datamonkey: rapid detection of selective pressure on individual sites of codon alignments. Bioinformatics 21, 2531-2533.
28. Refsland, E. W. & Harris, R. S. (2013). The APOBEC3 family of retroelement restriction factors. Curr Top Microbiol Immunol 371, 1-27.
29. Sheehy, A. M., Gaddis, N. C., Choi, J. D. & Malim, M. H. (2002). Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418, 646-650.
30. Shimojima, M., Miyazawa, T., Ikeda, Y., McMonagle, E. L., Haining, H., Akashi, H., Takeuchi, Y., Hosie, M. J. & Willett, B. J. (2004). Use of CD134 as a primary receptor by the feline immunodeficiency virus. Science 303, 1192-1195.
31. Stern, M. A., Hu, C., Saenz, D. T., Fadel, H. J., Sims, O., Peretz, M. & Poeschla, E. M. (2010). Productive replication of Vif-chimeric HIV-1 in feline cells. J Virol 84, 7378-7395.
32. Tahirov, T. H., Inoue-Bungo, T., Morii, H., Fujikawa, A., Sasaki, M., Kimura, K., Shiina, M., Sato, K., Kumasaka, T. & other authors (2001). Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104, 755-767.
33. Wang, J., Zhang, W., Lv, M., Zuo, T., Kong, W. & Yu, X. (2011). Identification of a Cullin5-ElonginB-ElonginC E3 complex in degradation of feline immunodeficiency virus Vif-mediated feline APOBEC3 proteins. J Virol 85, 12482-12491.
34. Yan, J., Liu, Y., Lukasik, S. M., Speck, N. A. & Bushweller, J. H. (2004). CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium. Nat Struct Mol Biol 11, 901-906.
35. Zhang, H., Yang, B., Pomerantz, R. J., Zhang, C., Arunachalam, S. C. & Gao, L. (2003). The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 424, 94-98.
36. Zhang, W., Du, J., Evans, S. L., Yu, Y. & Yu, X. F. (2012). T-cell differentiation factor CBF-b regulates HIV-1 Vif-mediated evasion of host restriction. Nature 481, 376-379.
37. Zhang, W., Wang, H., Li, Z., Liu, X., Liu, G., Harris, R. S. & Yu, X. F. (2014). Cellular requirements for bovine immunodeficiency virus Vifmediated inactivation of bovine APOBEC3 proteins. J Virol 88, 12528-12540.
38. Zielonka, J. & Münk, C. (2011). Cellular restriction factors of feline immunodeficiency virus. Viruses 3, 1986-2005.
39. Zielonka, J., Marino, D., Hofmann, H., Yuhki, N., Löchelt, M. & Münk, C. (2010). Vif of feline immunodeficiency virus from domestic cats protects against APOBEC3 restriction factors from many felids. J Virol 84, 7312-7324.