Effects of exposure to benzo[a]pyrene on metastasis of breast cancer are mediated through ROS-ERK-MMP9 axis signaling

Toxicology Letters

Volumn 234, Issue 3, 2015, Pages 201-210

  Guo, Jingyu ^a   Xu, Yi ^a   Ji, Weiwei ^a   Song, Lele ^a   Dai, Cheng ^a   Zhan, Lixing ^a,b  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Benzo a pyrene; Breast cancer metastasis; ERK; MMP9; ROS

Indexed keywords

BENZO[A]PYRENE; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; CARCINOGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DISTANT METASTASIS; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR INVASION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; CELL MOTION; CHEMICALLY INDUCED; DRUG EFFECTS; EXPERIMENTAL MAMMARY NEOPLASM; METABOLISM; METASTASIS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BENZO(A)PYRENE; BREAST NEOPLASMS; CARCINOGENS; CELL MOVEMENT; FEMALE; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84924974865     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.02.016     Document Type: Article

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