In vitro cytotoxicity of gold nanorods in A549 cells

Environmental Toxicology and Pharmacology

Volumn 39, Issue 2, 2015, Pages 871-878

  Tang, Ying ^a   Shen, Yafeng ^a   Huang, Libin ^a   Lv, Gaojian ^b   Lei, Changhai ^a   Fan, Xiaoyan ^a   Lin, Fangxing ^a   Zhang, Yuxia ^a   Wu, Lihui ^c   Yang, Yongji ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

A549 cells; Cytotoxicity; Gold nanorods; Laser scanning confocal microscope (LSCM); Transmission electron microscope (TEM)

Indexed keywords

GOLD NANOPARTICLE; GOLD; LACTATE DEHYDROGENASE; NANOTUBE; REACTIVE OXYGEN METABOLITE;

A549 CELL LINE; ARTICLE; CELL LEVEL; CELL MEDIATED CYTOTOXICITY; CELL MEMBRANE; CELL STRUCTURE; CELL VACUOLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; CELL SURVIVAL; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE; ULTRASTRUCTURE;

CELL LINE, TUMOR; CELL SURVIVAL; GOLD; HUMANS; L-LACTATE DEHYDROGENASE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES; REACTIVE OXYGEN SPECIES;

EID: 84924939592     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2015.02.003     Document Type: Article

References (30)

1. Aibo liu, ye B. Application of gold nanoparticles in biomedical researches and diagnosis. Clin. Lab. 2013, 59:23-26.
2. Aueviriyavit S., Phummiratch D., Maniratanachote R. Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells - induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles. Toxicol. Lett. 2014, 224:73-83.
3. Devika Chithrani B., Arezou A., Ghazani, Chan W.C.W. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Letters 2006, 6:662-668.
4. Beer C., Foldbjerg R., Hayashi Y., Sutherland D.S., Autrup H. Toxicity of silver nanoparticles - nanoparticle or silver ion?. Toxicol. Lett. 2012, 208:286-292.
5. Brumfiel, G., 2003. A little knowledge. . Nature 424, 246-249.
6. Catherine Murphy, Gole Anand m., Stone John w., Sisico Patrick, Alkilany A.M., Goldsmith Edie C., Baxter S.C. Gold nanoparticles in biology beyond toxicity to cellular imaging. Acc. Chem. Res. 2008, 41:1721-1730.
7. Chithrani B.D., Chan W.C.W. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Letters 2007, 7:1542-1550.
8. Chuang S.M., Lee Y.H., Liang R.Y., Roam G.D., Zeng Z.M., Tu H.F., Wang S.K., Chueh P.J. Extensive evaluations of the cytotoxic effects of gold nanoparticles. Biochim. Biophys. Acta 2013, 1830:4960-4973.
9. Chueh P.J., Liang R.Y., Lee Y.H., Zeng Z.M., Chuang S.M. Differential cytotoxic effects of gold nanoparticles in different mammalian cell lines. J. Hazard. Mater. 2014, 264:303-312.
10. Connor E.E., Mwamuka J., Gole A., Murphy C.J., Wyatt M.D. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005, 1:325-327.
11. Daniel M.-C., Astruc D. Gold nanoparticles assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chem. Rev. 2004, 104:293-346.
12. Foldbjerg R., Dang D.A., Autrup H. Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549. Arch. Toxicol. 2011, 85:743-750.
13. Gannon C.J., Patra C.R., Bhattacharya R., Mukherjee P., Curley S.A. Intracellular gold nanoparticles enhance non-invasive radiofrequency thermal destruction of human gastrointestinal cancer cells. J. Nanobiotechnol. 2008, 6:2.
14. Hauck T.S., Ghazani A.A., Chan W.C. Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small 2008, 4:153-159.
15. Huang X., Jain P.K., El-Sayed I.H., El-Sayed M.A. Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med. Sci. 2008, 23:217-228.
16. Foster Kimberly A., Oster Christine G., Mayer Mary M., Avery Michael L., Audus K.L. Characterization of the A549 cell line as a type ii pulmonary epithelial cell model for drug metabolism. Exp. Cell Res. 1998, 243:359-366.
17. Lieber M., Smith B., Szakal A., Nelson-Rees W., Todaro G. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. J. Int. Cancer 1976, 17:62-70.
18. Murphy C.J., Gole A.M., Hunyadi S.E., Stone J.W., Sisco P.N., Alkilany A., Kinard B.E., Hankins P. Chemical sensing and imaging with metallic nanorods. Chem. Commun. 2008, 544-557.
19. Paino I.M., Marangoni V.S., de Oliveira Rde C., Antunes L.M., Zucolotto V. Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells. Toxicol. Lett. 2012, 215:119-125.
20. Pan Y., Neuss S., Leifert A., Fischler M., Wen F., Simon U., Schmid G., Brandau W., Jahnen-Dechent W. Size-dependent cytotoxicity of gold nanoparticles. Small 2007, 3:1941-1949.
21. Pernodet N., Fang X., Sun Y., Bakhtina A., Ramakrishnan A., Sokolov J., Ulman A., Rafailovich M. Adverse effects of citrate/gold nanoparticles on human dermal fibroblasts. Small 2006, 2:766-773.
22. Purohit R., Vallabani N.V., Shukla R.K., Kumar A., Dhawan A., Singh S. BSA coated gold nanoparticles exhibit size dependent interaction with lung cancer (A549) cells. Mol. Cytogenetics 2014, 7:P83.
23. Ravi Shukla, Vipul Bansal, Minakshi Chaudhary, Basu A., Bhonde Ramesh R., Sastry M. Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment a microscopic overview. Langmuir 2005, 21:10644-10654.
24. Rothen-Rutishauser B., Muhlfeld C., Blank F., Musso C., Gehr P. Translocation of particles and inflammatory responses after exposure to fine particles and nanoparticles in an epithelial airway model. Particle Fibre Toxicol. 2007, 4:9.
25. Roy R., Kumar S., Tripathi A., Das M., Dwivedi P.D. Interactive threats of nanoparticles to the biological system. Immunol. Lett. 2014, 158:79-87.
26. Serice R.F. Nanomaterials show signs of toxicity. Science 2003, 300:243.
27. Takenaka S., Karg E., Kreyling W.G., Lentner B., Moller W., Behnke-Semmler M., Jennen L., Walch A., Michalke B., Schramel P., Heyder J., Schulz H. Distribution pattern of inhaled ultrafine gold particles in the rat lung. Inhal. Toxicol. 2006, 18:733-740.
28. Uboldi C., Bonacchi D., Lorenzi G., Hermanns M.I., Pohl C., Baldi G., Unger R.E., Kirkpatrick C.J. Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. Particle Fibre Toxicol. 2009, 6:18.
29. Verma A., Uzun O., Hu Y., Hu Y., Han H.S., Watson N., Chen S., Irvine D.J., Stellacci F. Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nat. Mater. 2008, 7:588-595.
30. Yen H.J., Hsu S.H., Tsai C.L. Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Small 2009, 5:1553-1561.